scholarly journals Genetic expression of MMP-Matrix-mettalo-proteinases (MMP-1 and MMP-13) as a function of anterior mandibular repositioning appliance on the growth of mandibular condylar cartilage with and without administration of Insulin like growth factor (IGF-1) and Transforming growth factor-B (TGF-β)

2012 ◽  
Vol 82 (6) ◽  
pp. 1053-1059 ◽  
Author(s):  
Amol Patil ◽  
Ravindranath Sable ◽  
Ramanlal Kothari
2004 ◽  
Vol 83 (3) ◽  
pp. 245-249 ◽  
Author(s):  
J. Watahiki ◽  
T. Yamaguchi ◽  
T. Irie ◽  
H. Nakano ◽  
K. Maki ◽  
...  

Little is known about the mechanisms of mandibular condylar growth. In this study, gene expression in the mandibular condylar cartilage of young post-natal mice was monitored by means of a cDNA microarray, real-time PCR, and laser microdissection before and after the initiation of mastication (newborn, 7 days, 21 days, initiation of mastication, and 35 days). Insulin-like growth factor-1 (IGF-I), transforming-growth-factor-beta-2 (TGFbeta2), and aggrecan mRNAs were clearly expressed at 21 days, while the expression of osteopontin mRNAs was most clear at 35 days. Parathyroid-hormone-related protein (PTHrP), Indian-hedgehog (Ihh), and insulin-like growth factor-2 (IGF-2) mRNAs were clearly expressed during lactation (newborn and 7 days). Heat-shock-protein 84 (HSP-84) and heat-shock-protein 86 (HSP-86) were clearly expressed at 35 days. These results revealed that gene expression changed during mandibular condylar cartilage growth, and that, interestingly, these changes coincided with the initiation of mastication.


1987 ◽  
Vol 262 (5) ◽  
pp. 1946-1949 ◽  
Author(s):  
S.M. Seyedin ◽  
P.R. Segarini ◽  
D.M. Rosen ◽  
A.Y. Thompson ◽  
H. Bentz ◽  
...  

2002 ◽  
Vol 36 ◽  
pp. 69
Author(s):  
Javier Crespo ◽  
Amalia Cayon ◽  
Marta Mayorga ◽  
Agustin Dominguez-Diez ◽  
Manuel Hernandez-Guerra ◽  
...  

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