Effects of Wall Thickness and Elastic Modulus in Fluid Structure Interaction of Patient Specific Cerebral Aneurysm

2012 ◽  
Author(s):  
Alvaro Valencia ◽  
Hernan Figueroa ◽  
Rodrigo Rivera ◽  
Eduardo Bravo
Keyword(s):  
Elastic Modulus ◽  
Cerebral Aneurysm ◽  
Wall Thickness ◽  
Fluid Structure Interaction ◽  
Patient Specific ◽  
Fluid Structure ◽  
Structure Interaction

scholarly journals Fluid-Structure Interaction Simulation of an Intra-Atrial Fontan Connection

Biology ◽  
2020 ◽  
Vol 9 (12) ◽  
pp. 412
Author(s):  
Elaine Tang ◽  
Zhenglun (Alan) Wei ◽  
Mark A. Fogel ◽  
Alessandro Veneziani ◽  
Ajit P. Yoganathan
Keyword(s):  
Magnetic Resonance ◽  
Power Loss ◽  
Phase Contrast ◽  
Fluid Structure Interaction ◽  
Rigid Wall ◽  
Patient Specific ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Wall Deformation ◽  
Wall Compliance

Total cavopulmonary connection (TCPC) hemodynamics has been hypothesized to be associated with long-term complications in single ventricle heart defect patients. Rigid wall assumption has been commonly used when evaluating TCPC hemodynamics using computational fluid dynamics (CFD) simulation. Previous study has evaluated impact of wall compliance on extra-cardiac TCPC hemodynamics using fluid-structure interaction (FSI) simulation. However, the impact of ignoring wall compliance on the presumably more compliant intra-atrial TCPC hemodynamics is not fully understood. To narrow this knowledge gap, this study aims to investigate impact of wall compliance on an intra-atrial TCPC hemodynamics. A patient-specific model of an intra-atrial TCPC is simulated with an FSI model. Patient-specific 3D TCPC anatomies were reconstructed from transverse cardiovascular magnetic resonance images. Patient-specific vessel flow rate from phase-contrast magnetic resonance imaging (MRI) at the Fontan pathway and the superior vena cava under resting condition were prescribed at the inlets. From the FSI simulation, the degree of wall deformation was compared with in vivo wall deformation from phase-contrast MRI data as validation of the FSI model. Then, TCPC flow structure, power loss and hepatic flow distribution (HFD) were compared between rigid wall and FSI simulation. There were differences in instantaneous pressure drop, power loss and HFD between rigid wall and FSI simulations, but no difference in the time-averaged quantities. The findings of this study support the use of a rigid wall assumption on evaluation of time-averaged intra-atrial TCPC hemodynamic metric under resting breath-held condition.

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