Predominant Dermoscopic Patterns Observed among Nevi

2006 ◽  
Vol 10 (4) ◽  
pp. 170-174 ◽  
Author(s):  
Alon Scope ◽  
Marco Burroni ◽  
Anna Liza Chan Agero ◽  
Cristiane Benvenuto-Andrade ◽  
Stephen W. Dusza ◽  
...  
Keyword(s):  
Global Pattern ◽  
Dominant Pattern ◽  
Global Patterns ◽  
Homogeneous Pattern ◽  
A Minor ◽  
Minor Pattern

Background: It has been clinically observed that patients' “normal” moles resemble each other. Whether this concept is applicable to dermoscopic practice has not been sufficiently studied. Objective: To investigate whether physicians evaluating dermoscopic images would identify common dermoscopic profiles of nevi within individual patients. Methods: Images of 205 nevi belonging to 18 patients were evaluated by 2 dermatologists for dermoscopic global pattern, color, and specific structures. We defined dermoscopic patterns as dominant if seen in ≥ 40% of the patient's nevi; a minor pattern was defined as 20 to 39%. Results: A dominant pattern was seen in 15 patients (83%). In 13 (72%) of the patients, ≥ 80% of the nevi were classified into one, two, or three global patterns. The reticular global pattern was the most prevalent dominant pattern, seen in 9 patients (50%); the homogeneous pattern was the most prevalent minor pattern, seen in 16 patients (89%). Conclusion: Individuals tend to have one to three predominant dermoscopic nevus global patterns.

scholarly journals Effects of embryo culture on global pattern of gene expression in preimplantation mouse embryos

Reproduction ◽  
2004 ◽  
Vol 128 (3) ◽  
pp. 301-311 ◽  
Author(s):  
Paolo Rinaudo ◽  
Richard M Schultz
Keyword(s):  
Gene Expression ◽  
Preimplantation Embryos ◽  
Expression Analysis Systematic Explorer ◽  
Cell Stage ◽  
Global Pattern ◽  
Preimplantation Mouse Embryos ◽  
Preimplantation Mouse ◽  
Global Patterns ◽  
The One

Culture of preimplantation embryos affects gene expression. The magnitude of the effect on the global pattern of gene expression, however, is not known. We compared global patterns of gene expression in blastocysts cultured from the one-cell stage in either Whitten’s medium or KSOM + amino acids (KSOM/AA) with that of blastocysts that developed in vivo, using the Affymetrix MOE430A chip. The analysis revealed that expression of 114 genes was affected after culture in Whitten’s medium, whereas only 29 genes were mis-expressed after culture in KSOM/AA. Expression Analysis Systematic Explorer was used to identify biological and molecular processes that are perturbed after culture and indicated that genes involved in protein synthesis, cell proliferation and transporter function were down-regulated after culture in Whitten’s medium. A common set of genes involved in transporter function was also down-regulated after culture in KSOM/AA. These results provide insights as to why embryos develop better in KSOM/AA than in Whitten’s medium, and highlight the power of microarray analysis to assess global patterns of gene expression.

A Dorsal Visual Route Necessary for Global Form Perception: Evidence from Neuropsychological fMRI

2014 ◽  
Vol 26 (3) ◽  
pp. 621-634 ◽  
Author(s):  
Vaia Lestou ◽  
Judith Mi Lin Lam ◽  
Katie Humphreys ◽  
Zoe Kourtzi ◽  
Glyn W. Humphreys
Keyword(s):  
Visual Processing ◽  
Form Perception ◽  
Dorsal Cortex ◽  
Global Pattern ◽  
Local Integration ◽  
Global Patterns ◽  
Cortical Regions ◽  
High Level ◽  
Glass Patterns ◽  
Pattern Coding

Hierarchical models of visual processing assume that global pattern recognition is contingent on the progressive integration of local elements across larger spatial regions, operating from early through intermediate to higher-level cortical regions. Here, we present results from neuropsychological fMRI that refute such models. We report two patients, one with lesions to intermediate ventral regions and the other with damage around the intraparietal sulcus (IPS). The patient with ventral damage showed normal behavioral and BOLD responses to global Glass patterns. The patient with IPS damage was impaired in discriminating global patterns and showed a lack of significant responses to these patterns in intermediate visual regions spared by the lesion. However, this patient did show BOLD activity to translational patterns, where local element relations are important. These results suggest that activation of intermediate ventral regions is not necessary to code global patterns; instead global patterns are coded in a heterarchical fashion. High-level regions of dorsal cortex are necessary to generate global pattern coding in intermediate ventral regions; in contrast, local integration processes are not sufficient.

scholarly journals Slow and steady: the evolution of cranial disparity in fossil and recent turtles

2016 ◽  
Vol 283 (1843) ◽  
pp. 20161881 ◽  
Author(s):  
Christian Foth ◽  
Walter G. Joyce
Keyword(s):  
Global Warming ◽  
Geometric Morphometrics ◽  
Fossil Record ◽  
Habitat Destruction ◽  
Late Triassic ◽  
Diverse Group ◽  
Two Dimensional ◽  
Global Patterns ◽  
A Minor

Turtles (Testudinata) are a diverse group of amniotes that have a rich fossil record that extends back to the Late Triassic, but little is known about global patterns of disparity through time. We here investigate the cranial disparity of 172 representatives of the turtle lineage and their ancestors grouped into 20 time bins ranging from the Late Triassic until the Recent using two-dimensional geometric morphometrics. Three evolutionary phases are apparent in all three anatomical views investigated. In the first phase, disparity increases gradually from the Late Triassic to the Palaeogene with only a minor perturbation at the K/T extinct event. Although global warming may have influenced this increase, we find the Mesozoic fragmentation of Pangaea to be a more plausible factor. Following its maximum, disparity decreases strongly towards the Miocene, only to recover partially towards the Recent. The marked collapse in disparity is likely a result of habitat destruction caused by global drying, combined with the homogenization of global turtle faunas that resulted from increased transcontinental dispersal in the Tertiary. The disparity minimum in the Miocene is likely an artefact of poor sampling.

Basic valency orientation and the middle voice in Hittite

2012 ◽  
Vol 36 (1) ◽  
pp. 1-32 ◽  
Author(s):  
Silvia Luraghi
Keyword(s):  
Limited Extent ◽  
Original Function ◽  
Middle Voice ◽  
High Productivity ◽  
European Languages ◽  
Change Of State ◽  
Transitive Verbs ◽  
Intransitive Verbs ◽  
A Minor ◽  
Minor Pattern

This paper discusses basic valency orientation in Hittite, based on the typology proposed in Nichols et al. (2004). Verb pairs usually employed to test basic valency indicate the clearly transitivizing character of this language; a closer scrutiny of intransitive verbs further reveals the existence of a three-fold distinction featuring two intransitive verbs, a basic stative one (or an adjective), and an overtly marked intransitive change-of-state, in addition to a transitive counterpart overtly marked as causative. The high productivity of causative derivation is shown by the fact that morphologically marked causatives are not only derived from stative verbs, but also from telic intransitives and from transitive verbs. In the case of telic intransitive verbs, a minor pattern is also attested, whereby valency alternation is encoded through voice alternation, with intransitive forms inflected in the middle voice and transitive forms in the active. Since neither voice can be considered to be derived with respect to the other, verbs that display this behavior are indeterminate as to basic valency orientation. In spite of the limited extent to which voice indicates valency alternation, this finding becomes more significant when set into the framework of valency alternation in the early Indo-European languages, and sheds some light (or raises more questions) on the original function of the Hittite and of the Indo-European middle voice, a typologically puzzling category.

Rating Post-Operative Backs (Part I)

1997 ◽  
Vol 2 (4) ◽  
pp. 1-3
Author(s):  
James B. Talmage
Keyword(s):  
Spinal Stenosis ◽  
Foot Drop ◽  
Neurogenic Claudication ◽  
Root Damage ◽  
Fourth Edition ◽  
Minor Strain ◽  
Injury Model ◽  
Strain Type ◽  
A Minor ◽  
Anterior Tibialis

Abstract The AMA Guides to the Evaluation of Permanent Impairment, Fourth Edition, uses the Injury Model to rate impairment in people who have experienced back injuries. Injured individuals who have not required surgery can be rated using differentiators. Challenges arise when assessing patients whose injuries have been treated surgically before the patient is rated for impairment. This article discusses five of the most common situations: 1) What is the impairment rating for an individual who has had an injury resulting in sciatica and who has been treated surgically, either with chemonucleolysis or with discectomy? 2) What is the impairment rating for an individual who has a back strain and is operated on without reasonable indications? 3) What is the impairment rating of an individual with sciatica and a foot drop (major anterior tibialis weakness) from L5 root damage? 4) What is the rating for an individual who is injured, has true radiculopathy, undergoes a discectomy, and is rated as Category III but later has another injury and, ultimately, a second disc operation? 5) What is the impairment rating for an older individual who was asymptomatic until a minor strain-type injury but subsequently has neurogenic claudication with severe surgical spinal stenosis on MRI/myelography? [Continued in the September/October 1997 The Guides Newsletter]

Pelvic Impairments

2018 ◽  
Vol 23 (4) ◽  
pp. 9-10
Author(s):  
James Talmage ◽  
Jay Blaisdell
Keyword(s):  
Pelvic Ring ◽  
Reproductive Organs ◽  
High Impact ◽  
Pelvic Fractures ◽  
Motor Dysfunction ◽  
Impact Event ◽  
Concomitant Injuries ◽  
Rating Process ◽  
Pass Through ◽  
A Minor

Abstract Pelvic fractures are relatively uncommon, and in workers’ compensation most pelvic fractures are the result of an acute, high-impact event such as a fall from a roof or an automobile collision. A person with osteoporosis may sustain a pelvic fracture from a lower-impact injury such as a minor fall. Further, major parts of the bladder, bowel, reproductive organs, nerves, and blood vessels pass through the pelvic ring, and traumatic pelvic fractures that result from a high-impact event often coincide with damaged organs, significant bleeding, and sensory and motor dysfunction. Following are the steps in the rating process: 1) assign the diagnosis and impairment class for the pelvis; 2) assign the functional history, physical examination, and clinical studies grade modifiers; and 3) apply the net adjustment formula. Because pelvic fractures are so uncommon, raters may be less familiar with the rating process for these types of injuries. The diagnosis-based methodology for rating pelvic fractures is consistent with the process used to rate other musculoskeletal impairments. Evaluators must base the rating on reliable data when the patient is at maximum medical impairment and must assess possible impairment from concomitant injuries.

The Effect of Path Length and Display Size on Memory for Spatial Information

2012 ◽  
Vol 59 (3) ◽  
pp. 147-152 ◽  
Author(s):  
Katherine Guérard ◽  
Sébastien Tremblay
Keyword(s):  
Path Length ◽  
Potential Role ◽  
Spatial Information ◽  
Recall Performance ◽  
Minor Role ◽  
Length Effect ◽  
Serial Memory ◽  
Fixed Reference ◽  
A Minor

In serial memory for spatial information, some studies showed that recall performance suffers when the distance between successive locations increases relatively to the size of the display in which they are presented (the path length effect; e.g., Parmentier et al., 2005) but not when distance is increased by enlarging the size of the display (e.g., Smyth & Scholey, 1994). In the present study, we examined the effect of varying the absolute and relative distance between to-be-remembered items on memory for spatial information. We manipulated path length using small (15″) and large (64″) screens within the same design. In two experiments, we showed that distance was disruptive mainly when it is varied relatively to a fixed reference frame, though increasing the size of the display also had a small deleterious effect on recall. The insertion of a retention interval did not influence these effects, suggesting that rehearsal plays a minor role in mediating the effects of distance on serial spatial memory. We discuss the potential role of perceptual organization in light of the pattern of results.

Psychoanalysis—A Minor Classic

1956 ◽  
Vol 1 (12) ◽  
pp. 366-367
Author(s):  
EPHRAIM ROSEN
Keyword(s):  
A Minor

Social Psychology As A Minor Footnote

1978 ◽  
Vol 23 (5) ◽  
pp. 376-377 ◽  
Author(s):  
HENRI TAJFEL
Keyword(s):  
Social Psychology ◽  
A Minor
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