Mesotherapy-Induced Panniculitis Treated with Dapsone: Case Report and Review of Reported Adverse Effects of Mesotherapy

2006 ◽  
Vol 10 (2) ◽  
pp. 92-95 ◽  
Author(s):  
Jennifer Tan ◽  
Babar Rao

Background: Mesotherapy is a procedure involving the injection of substances into the dermis and subcutaneous tissue. Used in Europe for decades in the treatment of various medical conditions and cosmetic fat dissolution, the technique only recently became widely available in the United States. Mesotherapy has been surrounded by controversy pertaining to efficacy and has been associated with localized complications, including allergic reactions, necrosis, and infections. Panniculitis is a rare adverse reaction to mesotherapy that may result from injection pressure, local trauma, or the type of injected substances. Objective: Treatment options for complications are limited. We report a case of mesotherapy-induced panniculitis successfully treated with dapsone. Conclusion: This case illustrates one of the potential adverse effects of mesotherapy and suggests that dapsone may be effective in the treatment of panniculitis resulting from such injections. Reported adverse effects associated with mesotherapy are also reviewed.

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Rojeh Melikian ◽  
Sofia Yeremian

Adjacent segment disease (ASD) in the lumbar spine is a possible consequence in segments adjacent to a fusion. As the number of lumbar fusions in the United States increases, the rates of ASD will continue to climb. There are several treatment options for ASD with open decompression and extension of the fusion being common. However, need for exposure and removal of existing instrumentation can lead to increased operative times resulting in increasing blood loss and infection risk. The purpose of this paper is to describe a case report for unilateral cortical trajectory screw instrumentation, allowing for posterior instrumentation without having to remove the existing pedicle screws in the setting of ASD. Our technique can be done with standard c-arm fluoroscopy without the need for navigation.


2021 ◽  
Vol 9 ◽  
pp. 232470962110132
Author(s):  
Parth J. Sampat ◽  
Maneesh Bisen ◽  
Nimisha Srivastava ◽  
Suman Rao ◽  
Teresa Gentile

Multiple myeloma is the second most common hematological malignancy. Ixazomib is the first oral proteasome inhibitor approved in the United States for the management of multiple myeloma who have received at least one prior treatment. The availability of oral chemotherapeutic agents for the management of multiple myeloma has made it easier for patients who do not have to come to the hospital for chemotherapy infusions. However, many barriers are associated with oral chemotherapy, and one of them is a misinterpretation of instruction which can have deleterious effects. In this case report, we present a case of a 69-year-old male with multiple myeloma who accidentally took ixazomib daily for 3 days instead of the weekly regimen and thus coming into the hospital with an overdose. In this report, we focus on the adverse effects associated with ixazomib toxicity and how to manage the adverse reactions. Although there is no antidote available for ixazomib, supportive care is very essential in these patients.


2019 ◽  
Vol 59 (5) ◽  
pp. 284-8
Author(s):  
Felicia Anita Wijaya ◽  
I Gde Doddy Kurnia Indrawan

Unintentional drowning is the sixth most common cause of accidental death, accounting for 4,086 deaths (1.4 per 100,000) in the United States in 2007.1 In children, drowning is the second leading cause of injury-related death, and those aged 1–3 years have the highest rate of drowning.2 More than 1,400 pediatric drownings were reported in the United States in 2008.3 Many drowning deaths are due to lack of supervision in the bathtub, unprotected access to a pool, or lack of swimming skills.3 For every death by drowning, six children are hospitalized for drowning, and up to 10% of survivors experience severe brain damage.2


Author(s):  
Jutta Lindert ◽  
Kimberley C. Paul ◽  
E. Lachman Margie ◽  
Beate Ritz ◽  
Teresa Seeman

AbstractLimited research is available on the relationship between social stress and risk of declining cognition. We sought to examine whether social stress has adverse effects on risk of declining episodic memory and executive functioning in aging individuals. We used data from the MIDUS study, a national probability sample of non-institutionalized, English speaking respondents aged 25–74 living in the 48 contiguous states of the United States. The initial wave (1995) included 4963 non-institutionalized adults aged 32–84 (M = 55, SD = 12.4). We used an analytic sample from MIDUS-II (1996/1997) and MIDUS-III (2013) (n = 1821). The dependent variables are episodic memory and executive functioning, which were assessed with the Brief Test for Cognition (BTACT). The independent variables were social stress variables (subjective social status, family and marital stress, work stress and discrimination). To evaluate episodic memory and executive functioning changes over a time period of 10 years, we estimated adjusted linear regression models. Women report significantly lower subjective social status and more discrimination stress than men across all age groups. Controlling for education and income, age, and baseline episodic memory and executive functioning, lower subjective social status had additional adverse effects on declines in episodic memory in men and women. Marital risk had adverse effects on episodic memory in men but not in women. Daily discrimination had adverse effects on executive functioning on all individuals. Public health strategies should focus on reducing social stress in a socio-ecological perspective. Especially, subjective social status and discrimination stress might be a target for prevention efforts.


2020 ◽  
Vol 42 (1) ◽  
pp. 110-112
Author(s):  
Alan E. Gross ◽  
Katie J. Suda ◽  
Jifang Zhou ◽  
Gregory S. Calip ◽  
Susan A. Rowan ◽  
...  

2003 ◽  
Vol 36 (7) ◽  
pp. e73-e80 ◽  
Author(s):  
Nasia Safdar ◽  
Daniel K. Young ◽  
David Andes

1968 ◽  
Vol 6 (3) ◽  
pp. 9-11

PENICILLIN ALLERGY - Intramuscular benzylpenicillin in conventional doses is remarkable for its lack of toxicity, although massive intravenous or intramuscular doses can cause serious toxic encephalopathies. Allergic reactions occur in 3 – 8% of patients.1 2 The most serious reaction is acute anaphylactic shock, which is estimated to cause 100–300 deaths yearly in the United States.3 Urticarial and, less frequently, maculo-papular, diffuse erythematous and other forms of skin eruption may occur within minutes or only after hours or days. Angioneurotic oedema, asthma, joint pains and swelling, and lacrimation may also be features of penicillin allergy.


2012 ◽  
Vol 3 (3) ◽  
pp. 101-107 ◽  
Author(s):  
Carrie W. Miller

Marijuana is one of the most widely used recreational substances in the United States, with high rates of use during peak childbearing years. Medical marijuana use is also becoming more widely accepted in the United States, with legalization in 17 states and the District of Columbia. The available literature suggests that maternal marijuana use during breastfeeding is associated with potentially negative outcomes for infants and children. Adverse effects can include feeding difficulty, lethargy, and delayed cognitive and motor development. Mothers considered heavy or chronic users of marijuana are advised to not breastfeed infants. The aim of this article is to examine the prevalence of marijuana use, the potential effects on breastfed infants, and current recommendations from lactation experts.


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