Pulmonary Carcinogenicity of Relatively Low Doses of Beta-Particle Radiation from Inhaled 144 CeO 2 in Rats

1996 ◽  
Vol 146 (5) ◽  
pp. 525 ◽  
Author(s):  
D. L. Lundgren ◽  
F. F. Hahn ◽  
W. C. Griffith ◽  
A. F. Hubbs ◽  
K. J. Nikula ◽  
...  
Keyword(s):  
Beta Particle ◽  
Low Doses ◽  
Particle Radiation

Measurements of Charge Collection Efficiency of p+/n Junction SiC Detectors

2005 ◽  
Vol 483-485 ◽  
pp. 1021-1024 ◽  
Author(s):  
Francesco Moscatelli ◽  
Andrea Scorzoni ◽  
Antonella Poggi ◽  
Mara Bruzzi ◽  
Stefano Lagomarsino ◽  
...  
Keyword(s):  
Silicon Carbide ◽  
Particle Physics ◽  
Collection Efficiency ◽  
Good Alternative ◽  
Beta Particle ◽  
Charge Collection ◽  
Reverse Voltage ◽  
Particle Radiation ◽  
Charge Collection Efficiency ◽  
Physics Experiments

Silicon carbide is a promising wide-gap material because of its excellent electrical and physical properties, which are very relevant to technological applications. In particular, silicon carbide can represent a good alternative to Si in applications like the inner tracking detectors of particle physics experiments [1]. In this work p+/n SiC diodes realized on a medium doped (1×1015 cm -3), 40 µm thick epitaxial layer are exploited as detectors and measurements of their charge collection properties under beta particle radiation from Sr90 source are presented. Preliminary results till 900 V reverse voltage show a good collection efficiency of 1700 e- and a collection length (ratio between collected charges and generated e-h pairs/µm) equal to the estimated width of the depleted region.

scholarly journals Calibration of beta-particle radiation instrumentation and sources

1988 ◽  
Author(s):  
John S Pruitt ◽  
Christopher G Soares ◽  
Margarete Ehrlich
Keyword(s):  
Beta Particle ◽  
Particle Radiation

scholarly journals Unconventional oil and gas development and ambient particle radioactivity

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Longxiang Li ◽  
Annelise J. Blomberg ◽  
John D. Spengler ◽  
Brent A. Coull ◽  
Joel D. Schwartz ◽  
...  
Keyword(s):  
Monitoring Network ◽  
The United States ◽  
Beta Radiation ◽  
Beta Particle ◽  
Gross Beta ◽  
Environmental Radiation ◽  
Oil And Gas Development ◽  
Particle Radiation ◽  
Unconventional Oil ◽  
Ambient Particle

Abstract Unconventional oil and natural gas development (UOGD) expanded extensively in the United States from the early 2000s. However, the influence of UOGD on the radioactivity of ambient particulate is not well understood. We collected the ambient particle radioactivity (PR) measurements of RadNet, a nationwide environmental radiation monitoring network. We obtained the information of over 1.5 million wells from the Enverus database. We investigated the association between the upwind UOGD well count and the downwind gross-beta radiation with adjustment for environmental factors governing the natural emission and transport of radioactivity. Our statistical analysis found that an additional 100 upwind UOGD wells within 20 km is associated with an increase of 0.024 mBq/m3 (95% confidence interval [CI], 0.020, 0.028 mBq/m3) in the gross-beta particle radiation downwind. Based on the published health analysis of PR, the widespread UOGD could induce adverse health effects to residents living close to UOGD by elevating PR.

scholarly journals A high-throughput alpha particle irradiation system for monitoring DNA damage repair, genome instability and screening in human cell and yeast model systems

2020 ◽  
Vol 48 (19) ◽  
pp. e111-e111
Author(s):  
Fintan K T Stanley ◽  
N Daniel Berger ◽  
Dustin D Pearson ◽  
John M Danforth ◽  
Hali Morrison ◽  
...  
Keyword(s):  
Dna Damage ◽  
High Throughput ◽  
Alpha Particle ◽  
Dna Damage Repair ◽  
Alpha Particles ◽  
Model Systems ◽  
Cycle Phase ◽  
Low Doses ◽  
Particle Radiation ◽  
Damage Repair

Abstract Ionizing radiation (IR) is environmentally prevalent and, depending on dose and linear energy transfer (LET), can elicit serious health effects by damaging DNA. Relative to low LET photon radiation (X-rays, gamma rays), higher LET particle radiation produces more disease causing, complex DNA damage that is substantially more challenging to resolve quickly or accurately. Despite the majority of human lifetime IR exposure involving long-term, repetitive, low doses of high LET alpha particles (e.g. radon gas inhalation), technological limitations to deliver alpha particles in the laboratory conveniently, repeatedly, over a prolonged period, in low doses and in an affordable, high-throughput manner have constrained DNA damage and repair research on this topic. To resolve this, we developed an inexpensive, high capacity, 96-well plate-compatible alpha particle irradiator capable of delivering adjustable, low mGy/s particle radiation doses in multiple model systems and on the benchtop of a standard laboratory. The system enables monitoring alpha particle effects on DNA damage repair and signalling, genome stability pathways, oxidative stress, cell cycle phase distribution, cell viability and clonogenic survival using numerous microscopy-based and physical techniques. Most importantly, this method is foundational for high-throughput genetic screening and small molecule testing in mammalian and yeast cells.

scholarly journals Long-Term Effects of Very Low Dose Particle Radiation on Gene Expression in the Heart: Degenerative Disease Risks

Cells ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 387
Author(s):  
Venkata Naga Srikanth Garikipati ◽  
Arsen Arakelyan ◽  
Eleanor A. Blakely ◽  
Polly Y. Chang ◽  
May M. Truongcao ◽  
...  
Keyword(s):  
Metabolic Diseases ◽  
Biological Response ◽  
Rna Isolation ◽  
Degenerative Disease ◽  
Low Doses ◽  
Long Term Effects ◽  
Bioinformatics Analyses ◽  
Particle Radiation ◽  
Tissue Samples ◽  
Linear Pattern

Compared to low doses of gamma irradiation (γ-IR), high-charge-and-energy (HZE) particle IR may have different biological response thresholds in cardiac tissue at lower doses, and these effects may be IR type and dose dependent. Three- to four-month-old female CB6F1/Hsd mice were exposed once to one of four different doses of the following types of radiation: γ-IR 137Cs (40-160 cGy, 0.662 MeV), 14Si-IR (4-32 cGy, 260 MeV/n), or 22Ti-IR (3-26 cGy, 1 GeV/n). At 16 months post-exposure, animals were sacrificed and hearts were harvested and archived as part of the NASA Space Radiation Tissue Sharing Forum. These heart tissue samples were used in our study for RNA isolation and microarray hybridization. Functional annotation of twofold up/down differentially expressed genes (DEGs) and bioinformatics analyses revealed the following: (i) there were no clear lower IR thresholds for HZE- or γ-IR; (ii) there were 12 common DEGs across all 3 IR types; (iii) these 12 overlapping genes predicted various degrees of cardiovascular, pulmonary, and metabolic diseases, cancer, and aging; and (iv) these 12 genes revealed an exclusive non-linear DEG pattern in 14Si- and 22Ti-IR-exposed hearts, whereas two-thirds of γ-IR-exposed hearts revealed a linear pattern of DEGs. Thus, our study may provide experimental evidence of excess relative risk (ERR) quantification of low/very low doses of full-body space-type IR-associated degenerative disease development.

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