Analysis of Radiation-Induced Micronuclei by Fluorescence In Situ Hybridization (FISH) Simultaneously Using Telomeric and Centromeric DNA Probes

1992 ◽  
Vol 131 (2) ◽  
pp. 177 ◽  
Author(s):  
B. M. Miller ◽  
T. Werner ◽  
H.-U. Weier ◽  
M. Nüsse ◽  
M. Nusse
BioTechniques ◽  
1999 ◽  
Vol 26 (6) ◽  
pp. 1068-1072
Author(s):  
Allen T. Christian ◽  
Holly E. Garcia ◽  
James D. Tucker

2003 ◽  
Vol 51 (4) ◽  
pp. 549-551 ◽  
Author(s):  
Anja Weise ◽  
Peter Harbarth ◽  
Uwe Claussen ◽  
Thomas Liehr

Fluorescence in situ hybridization (FISH) on human chromosomes in meta-and interphase is a well-established technique in clinical and tumor cytogenetics and for studies of evolution and interphase architecture. Many different protocols for labeling the DNA probes used for FISH have been published. Here we describe for the first time the successful use of Photoprobe biotin-labeled DNA probes in FISH experiments. Yeast artificial chromosome (YAC) and whole chromosome painting (wcp) probes were tested.


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