Radiation Resistance and the CuZn Superoxide Dismutase, Mn Superoxide Dismutase, Catalase, and Glutathione Peroxidase Activities of Seven Human Cell Lines

1984 ◽  
Vol 100 (1) ◽  
pp. 115 ◽  
Author(s):  
Stefan L. Marklund ◽  
N. Gunnar Westman ◽  
Göran Roos ◽  
Jörgen Carlsson ◽  
Goran Roos ◽  
...  
Keyword(s):  
Superoxide Dismutase ◽  
Glutathione Peroxidase ◽  
Cell Lines ◽  
Human Cell ◽  
Radiation Resistance ◽  
Human Cell Lines ◽  
Cuzn Superoxide Dismutase

Extracellular Glutathione Peroxidase mRNA and Protein in Human Cell Lines

1994 ◽  
Vol 309 (2) ◽  
pp. 239-246 ◽  
Author(s):  
N. Avissar ◽  
E.A. Kerl ◽  
S.S. Baker ◽  
H.J. Cohen
Keyword(s):  
Glutathione Peroxidase ◽  
Cell Lines ◽  
Human Cell ◽  
Human Cell Lines

scholarly journals Expression of extracellular superoxide dismutase by human cell lines

1990 ◽  
Vol 266 (1) ◽  
pp. 213-219 ◽  
Author(s):  
S L Marklund
Keyword(s):  
Superoxide Dismutase ◽  
Cell Lines ◽  
Human Cell ◽  
Heparan Sulphate ◽  
Cell Types ◽  
Tissue Cell ◽  
Extracellular Superoxide Dismutase ◽  
Human Cell Lines ◽  
Growing Cell ◽  
Dependent Cell

Extracellular superoxide dismutase (EC-SOD) is the major SOD isoenzyme in extracellular fluids, but occurs also in tissues. The sites and characteristics of the synthesis of the enzyme are unknown. The occurrence of EC-SOD in cultures of a large panel of human cell lines was assayed by means of an e.l.i.s.a. Unlike the situation for the intracellular isoenzymes CuZn-SOD and Mn-SOD, expression of EC-SOD occurs in only a few cell types. None of the ten investigated suspension-growing cell lines produced EC-SOD. Among normal diploid anchorage-dependent cell lines, expression was found in all 25 investigated fibroblast cell lines, in the two glia-cell lines, but not in six endothelial-cell lines, two epithelial-cell lines or in two amnion-derived lines. Among neoplastic anchorage-dependent cell lines expression was found in 13 out of 29. EC-SOD was secreted into the culture medium by cell lines expressing the enzyme. The rate of EC-SOD synthesis varied by nearly 100-fold among the fibroblast lines and remained essentially constant in the individual lines during long-term culture. In the nine investigated cases, the secreted EC-SOD was of the high-heparin-affinity C type. It is suggested that tissue EC-SOD is secreted by a few well-dispersed cell types, such as fibroblasts and glia cells, to diffuse subsequently around and reversibly bind to heparan sulphate proteoglycan ligands in the glycocalyx of the surface of most tissue cell types and in the interstitial matrix.

Investigations of the influence of microgravity on the state of human cell lines

2004 ◽  
Vol 10 (5-6) ◽  
pp. 226-228
Author(s):  
L.M. Nosach ◽  
◽  
O.Yu. Povnitsa ◽  
V.L. Zhovnovata ◽  
◽  
...  
Keyword(s):  
Cell Lines ◽  
Human Cell ◽  
The State ◽  
Human Cell Lines

scholarly journals Dicalcin suppresses in vitro trophoblast attachment in human cell lines

2021 ◽  
Vol 570 ◽  
pp. 206-213
Author(s):  
Ryohei Saito ◽  
Hiromasa Satoh ◽  
Kayo Aoba ◽  
Hajime Hirasawa ◽  
Naofumi Miwa
Keyword(s):  
Cell Lines ◽  
Human Cell ◽  
Human Cell Lines

scholarly journals Differential Effects of Cyanidin and Cyanidin-3-glucoside on Human Cell Lines

2011 ◽  
Vol 17 (6) ◽  
pp. 515-521 ◽  
Author(s):  
Masayuki TAKEUCHI ◽  
Katsuki OHTANI ◽  
Yanju MA ◽  
Sanae KATO ◽  
Shingo SEMBA ◽  
...  
Keyword(s):  
Cell Lines ◽  
Human Cell ◽  
Human Cell Lines ◽  
Differential Effects
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