The Role of Hydroxyl Radical Scavengers in Preventing DNA Strand Breaks Induced by X Irradiation of Toluene-Treated Escherichia coli

1984 ◽  
Vol 97 (3) ◽  
pp. 626 ◽  
Author(s):  
Daniel Billen
Keyword(s):  
Escherichia Coli ◽  
Hydroxyl Radical ◽  
Dna Strand Breaks ◽  
Radical Scavengers ◽  
Strand Breaks ◽  
X Irradiation ◽  
Dna Strand ◽  
Hydroxyl Radical Scavengers

Role of hydroxyl radical scavengers dimethyl sulfoxide, alcohols and methional in the inhibition of prostaglandin biosynthesis

1976 ◽  
Vol 11 (4) ◽  
pp. 599-607 ◽  
Author(s):  
Rao V. Panganamala ◽  
Hari M. Sharma ◽  
Richard E. Heikkila ◽  
Jack C. Geer ◽  
David G. Cornwell
Keyword(s):  
Hydroxyl Radical ◽  
Dimethyl Sulfoxide ◽  
Radical Scavengers ◽  
Prostaglandin Biosynthesis ◽  
Hydroxyl Radical Scavengers

scholarly journals The role of Sp1 in the detection and elimination of cells with persistent DNA strand breaks

NAR Cancer ◽  
2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Polina S Loshchenova ◽  
Svetlana V Sergeeva ◽  
Sally C Fletcher ◽  
Grigory L Dianov
Keyword(s):  
Dna Damage ◽  
Cancer Therapy ◽  
Genome Stability ◽  
Dna Strand Breaks ◽  
Dna Lesions ◽  
Exogenous Dna ◽  
Strand Breaks ◽  
Specificity Factor ◽  
Dna Strand

Abstract Maintenance of genome stability suppresses cancer and other human diseases and is critical for organism survival. Inevitably, during a life span, multiple DNA lesions can arise due to the inherent instability of DNA molecules or due to endogenous or exogenous DNA damaging factors. To avoid malignant transformation of cells with damaged DNA, multiple mechanisms have evolved to repair DNA or to detect and eradicate cells accumulating unrepaired DNA damage. In this review, we discuss recent findings on the role of Sp1 (specificity factor 1) in the detection and elimination of cells accumulating persistent DNA strand breaks. We also discuss how this mechanism may contribute to the maintenance of physiological populations of healthy cells in an organism, thus preventing cancer formation, and the possible application of these findings in cancer therapy.

Protective role of 3-nitrotyrosine against gamma radiation-induced DNA strand breaks: A comparison study with tyrosine

2008 ◽  
Vol 77 (10-12) ◽  
pp. 1290-1293
Author(s):  
Wei-Qun Shi ◽  
Mei-Nan Ni ◽  
Fu-Quan Kong ◽  
Li Sui ◽  
Jia Hu ◽  
...  
Keyword(s):  
Gamma Radiation ◽  
Dna Strand Breaks ◽  
Protective Role ◽  
Comparison Study ◽  
Strand Breaks ◽  
Radiation Induced ◽  
Dna Strand

Induction of DNA-strand breaks after X-irradiation in murine bone cells of various differentiation capacities

2005 ◽  
Vol 36 (9) ◽  
pp. 1689-1695
Author(s):  
Patrick Lau ◽  
Christine E. Hellweg ◽  
Simone Kirchner ◽  
Christa Baumstark-Khan
Keyword(s):  
Bone Cells ◽  
Dna Strand Breaks ◽  
Strand Breaks ◽  
X Irradiation ◽  
Dna Strand
Sign in / Sign up

Export Citation Format

Share Document