Association of Plutonium with Isolated Liver Parenchymal Cells Following Injection of Monomeric Plutonium into Mice

1976 ◽  
Vol 66 (3) ◽  
pp. 552 ◽  
Author(s):  
Maryka H. Bhattacharyya ◽  
Arthur Lindenbaum
Keyword(s):  
Liver Parenchymal ◽  
Parenchymal Cells ◽  
Isolated Liver

scholarly journals No major thermogenic role for (Na+ + K+)-dependent adenosine triphosphatase apparent in hepatocytes from hyperthyroid rats

1982 ◽  
Vol 202 (3) ◽  
pp. 661-665 ◽  
Author(s):  
D G Clark ◽  
M Brinkman ◽  
O H Filsell ◽  
S J Lewis ◽  
M N Berry
Keyword(s):  
Oxygen Consumption ◽  
Oxygen Uptake ◽  
Atpase Activity ◽  
Heat Production ◽  
Adenosine Triphosphatase ◽  
Heat Output ◽  
Liver Parenchymal ◽  
Dependent Atpase ◽  
Parenchymal Cells ◽  
Isolated Liver

(Na+ + K+)-dependent ATPase activity, heat production and oxygen consumption were increased by 59%, 62% and 75% respectively in hepatocytes from tri-iodothyronine-treated rats. Ouabain at concentrations of 1 and 10 mM decreased oxygen uptake by 2-8% in hepatocytes from euthyroid rats and by 5-15% in hepatocytes from hyperthyroid animals. Heat output was decreased by 4-9% with the glycoside in isolated liver parenchymal cells from the control animals and by 11% in the cells from the tri-iodothyronine-treated animals. These results do not support the hypothesis that hepatic (Na+ + K+)-ATPase plays a major role in increased heat production in hepatocytes from hyperthyroid rats.

Regulation of pyruvate kinase by 6-phosphogluconate in isolated hepatocytes

1981 ◽  
Vol 240 (3) ◽  
pp. E279-E285
Author(s):  
S. B. Smith ◽  
R. A. Freedland
Keyword(s):  
Pyruvate Kinase ◽  
Parenchymal Cell ◽  
Isolated Hepatocytes ◽  
Hill Coefficient ◽  
Liver Parenchymal Cell ◽  
Liver Parenchymal ◽  
Highly Correlated ◽  
Parenchymal Cells ◽  
The Hill ◽  
Isolated Liver

Isolated liver parenchymal cells from rats fed a 65% sucrose diet for 14 days were incubated in the presence and absence of 10(-6) M glucagon. The pyruvate kinase obtained from homogenates of the glucagon-treated cells displayed and increased Ks 0.5 for phosphoenolpyruvate (P-enolpyruvate), as well as an increased Ka 0.5 for 6-phosphogluconate (6-P-gluconate), compared to pyruvate kinase from untreated cells. Additionally, glucagon treatment decreased the maximal stimulation of pyruvate kinase by 6-P-gluconate by approximately two-thirds and decreased the Hill coefficient value of pyruvate kinase for 6-P-gluconate from 1.76 to 1.56. 6-Aminonicotinamide, an inhibitor of 6-P-gluconate dehydrogenase, increased 6-P-gluconate levels in isolated liver parenchymal cells three- to sevenfold, depending on the substrates present. The flux of P-enolpyruvate through pyruvate kinase was increased from 18 to 40% in these preparations and was highly correlated with the increase in 6-P-gluconate levels. The results suggest that 6-P-gluconate could regulate pyruvate kinase activity in the intact liver parenchymal cell. Furthermore, the activator would be of greatest importance in the lipogenic animal.

HORMONE SENSITIVITY OF ISOLATED LIVER PARENCHYMAL CELLS

1974 ◽  
Vol 77 (1_Suppl) ◽  
pp. S98 ◽  
Author(s):  
H. Bojar ◽  
K. Balzer ◽  
M. Stannek ◽  
W. Reipen ◽  
W. Staib
Keyword(s):  
Liver Parenchymal ◽  
Hormone Sensitivity ◽  
Parenchymal Cells ◽  
Isolated Liver

The importance of the techniques employed during the enzymatic preparation of isolated liver parenchymal cells

1973 ◽  
Vol 82 (3) ◽  
pp. 397-400 ◽  
Author(s):  
Douglas R. Labrecque ◽  
Nicholas R. Bachur ◽  
Janice A. Peterson ◽  
Roger B. Howard
Keyword(s):  
Enzymatic Preparation ◽  
Liver Parenchymal ◽  
Parenchymal Cells ◽  
Isolated Liver

Characteristics of lipoprotein receptors of the isolated liver parenchymal cells prepared from the streptozotocin-induced diabetic rats

Life Sciences ◽  
1986 ◽  
Vol 38 (7) ◽  
pp. 653-662 ◽  
Author(s):  
Tsuguhiko Nakai ◽  
Koji Oida ◽  
Toshitaka Tamai ◽  
Yasunori Kutsumi ◽  
Susumu Miyabo ◽  
...  
Keyword(s):  
Diabetic Rats ◽  
Lipoprotein Receptors ◽  
Liver Parenchymal ◽  
Parenchymal Cells ◽  
Isolated Liver

Bromsulfophthalein uptake by isolated liver parenchymal cells

1976 ◽  
Vol 69 (2) ◽  
pp. 354-361 ◽  
Author(s):  
C.F.A. van Bezooijen ◽  
T. Grell ◽  
D.L. Knook
Keyword(s):  
Liver Parenchymal ◽  
Parenchymal Cells ◽  
Isolated Liver
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