Influence of Ultrafast Repair Processes (Independent of DNA Polymerase I) on the Yield of DNA Single-Strand Breaks in Escherichia coli K-12 X-Irradiated in the Presence or Absence of Oxygen

1972 ◽  
Vol 52 (1) ◽  
pp. 99 ◽  
Author(s):  
Christopher D. Town ◽  
Kendric C. Smith ◽  
Henry S. Kaplan
Keyword(s):  
Escherichia Coli ◽  
Dna Polymerase ◽  
Single Strand ◽  
Dna Polymerase I ◽  
Strand Breaks ◽  
Repair Processes ◽  
Single Strand Breaks ◽  
K 12 ◽  
Polymerase I

THE INFLUENCE OF THE PO1A1 MUTATION UPON RECOMBINATION IN ESCHERICHIA COLI K12

1979 ◽  
Vol 21 (3) ◽  
pp. 423-428 ◽  
Author(s):  
Barry W. Glickman ◽  
Tineke Rutgers
Keyword(s):  
Escherichia Coli ◽  
Dna Polymerase ◽  
Genetic Recombination ◽  
Dna Polymerase I ◽  
Multiple Gene ◽  
E Coli ◽  
Recombinational Process ◽  
K 12 ◽  
Polymerase I

Genetic recombination in Escherichia coli is a highly regulated process involving multiple gene products. We have investigated the role of DNA polymerase I in this process by studying the effect of the po1A1 mutation upon DNA transfer and conjugation in otherwise isogenic suppressor-free strains of E. coli K-12. It was found that the po1A1 mutation greatly reduces recombination in Hfr crosses (a factor of 20 in Po1+ × Po1A1 crosses and more than a factor of 100 in Po1A1 × Po1A1 crosses). However, since the po1A1 mutation reduces the strains capacity to act as a recipient for an F-prime and the analysis of recombination transfer gradients revealed no differences between Po1+ and Po1− strains, it is concluded that DNA polymerase I probably affects the transfer and/or stability of donor DNA rather than the recombinational process itself.

scholarly journals Spontaneous and UV-induced mutations in Escherichia coli K-12 strains with altered or absent DNA polymerase I.

1989 ◽  
Vol 171 (5) ◽  
pp. 2480-2484 ◽  
Author(s):  
H Bates ◽  
S K Randall ◽  
C Rayssiguier ◽  
B A Bridges ◽  
M F Goodman ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Dna Polymerase ◽  
Induced Mutations ◽  
Dna Polymerase I ◽  
K 12 ◽  
Polymerase I

scholarly journals Trimethoprim-induced DNA polymerase I deficiency in Escherichia coli K-12.

1983 ◽  
Vol 154 (3) ◽  
pp. 1098-1103 ◽  
Author(s):  
P Mukhopadhyay ◽  
U Syrowik ◽  
S Palchaudhuri
Keyword(s):  
Escherichia Coli ◽  
Dna Polymerase ◽  
Dna Polymerase I ◽  
K 12 ◽  
Polymerase I
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