Studies on the Chemical Composition of the Central Nervous System in Relation to the Effects of X-Irradiation and of Disturbances in Water and Salt Balance: IV. Effects of X-Irradiation on the Chemical Composition of Rabbit Brain

1962 ◽  
Vol 17 (2) ◽  
pp. 244 ◽  
Author(s):  
George R. Rowley ◽  
Robert J. Dellenback ◽  
Victor Temnikow
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Chemical Composition ◽  
Rabbit Brain ◽  
Salt Balance ◽  
X Irradiation ◽  
The Central Nervous System ◽  
Water And Salt Balance

Observations on the Chemical Composition of Myelin and the Smallest Size of Myelinated Nerve-Fibres in the Central Nervous System

1948 ◽  
Vol s3-89 (5) ◽  
pp. 89-102
Author(s):  
A. BRODAL ◽  
R. G. HARRISON
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Chemical Composition ◽  
Nile Blue ◽  
Nerve Fibres ◽  
Myelinated Nerve ◽  
Myelin Sheaths ◽  
The Central Nervous System

Baker's (1946) acid haematein and pyridine-extraction control tests, claimed to be specific for phospholipines (Baker, 1947), have been applied to various parts of the central nervous system of rats and man. The sudan black method for the detection of lipoids and the nile blue method for the staining of acidic lipoids have also been used. The findings are in agreement with older statements in the literature that myelin contains a considerable amount of phospholipines. It was impossible to determine whether galactolipines or neutral lipoids are also present. In the acid haematein-stained sections finer fibres were seen than when other stains for myelin sheaths are employed. Fibres with a diameter of 0.5 µ or even somewhat less were stained in various parts of the central nervous system of rats. It is regarded as probable from these findings that fibres down to 0.5 µ or even smaller possess a lipoid investment. These observations lend support to the now commonly accepted view that the distinction between myelinated and so-called unmyelinated fibres is arbitrary. Some observations are made, however, which indicate that the presence of truly unmyelinated fibres cannot be excluded.

PATHOGENESIS OF LESIONS IN THE NERVOUS SYSTEM IN HYPERNATREMIC STATES

PEDIATRICS ◽  
1959 ◽  
Vol 23 (1) ◽  
pp. 46-53 ◽  
Author(s):  
Laurence Finberg ◽  
Charles Luttrell ◽  
Henry Redd
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Chemical Composition ◽  
Clinical Manifestations ◽  
Brain Cells ◽  
Intracranial Hemorrhages ◽  
The Central Nervous System ◽  
Inorganic Chemical ◽  
Relationship Of ◽  
Hypernatremic Dehydration

In an attempt to verify the possible causal relationship of hypernatremic dehydration and damage to the central nervous system and to study the mechanisms involved, kittens were made hypernatremic by injection with hypertonic solutions of sodium. Many of the clinical manifestations referable to the nervous system as seen in patients with hypernatremic dehydration were produced. Gross anatomic changes consisting of intracranial hemorrhages, such as are sometimes seen in patients, were also present in the animals. A study of the inorganic chemical composition of the tissues revealed a difference in the pattern of osmotic adjustment between cells of brain and of muscle. This is interpreted as a relative excess from development of idiogenic osmols within brain cells. It is suggested that this difference may in part account for the marked manifestations related to the nervous system seen in the animals and, by analogy, in patients.

Changes in the Central Nervous System after 700 R Total-Body X-Irradiation

1958 ◽  
Vol 8 (1) ◽  
pp. 92 ◽  
Author(s):  
W. O. Caster ◽  
E. S. Redgate ◽  
W. D. Armstrong
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
X Irradiation ◽  
The Central Nervous System ◽  
Total Body

scholarly journals THE RAPID PRODUCTION OF ACUTE DISSEMINATED ENCEPHALOMYELITIS IN RHESUS MONKEYS BY INJECTION OF HETEROLOGOUS AND HOMOLOGOUS BRAIN TISSUE WITH ADJUVANTS

1947 ◽  
Vol 85 (1) ◽  
pp. 117-130 ◽  
Author(s):  
Elvin A. Kabat ◽  
Abner Wolf ◽  
Ada E. Bezer
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Rhesus Monkeys ◽  
Demyelinating Disease ◽  
Acute Disseminated Encephalomyelitis ◽  
Rabbit Brain ◽  
Adult Rabbit ◽  
Rabbit Lung ◽  
The Central Nervous System ◽  
Experimental Findings

1. A picture resembling acute disseminated encephalomyelitis in the human being has been regularly and rapidly produced in rhesus monkeys by injection of emulsions of adult rabbit and monkey brain administered with adjuvants. 2. No lesions of the central nervous system resulted from injection of similar emulsions of fetal rabbit brain or adult rabbit lung. 3. A description of the gross and histological findings in the central nervous system is given and compared with features of human demyelinating disease. 4. The experimental findings are in accord with the hypothesis that antibody to the injected brain emulsion reacts with the tissues of the nervous system of the animal to produce the pathological changes.

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