The Effect of Ionizing Radiation on Amino Acids: I. The Effect of X-Rays on Aqueous Solutions of Glycine

1954 ◽  
Vol 1 (6) ◽  
pp. 530 ◽  
Author(s):  
Charles R. Maxwell ◽  
Dorothy C. Peterson ◽  
Norman E. Sharpless
Keyword(s):  
Amino Acids ◽  
Ionizing Radiation ◽  
Aqueous Solutions ◽  
X Rays

The Effect of Ionizing Radiation on Amino Acids: II. The Effect of X-Rays on Aqueous Solutions of Alanine

1955 ◽  
Vol 2 (2) ◽  
pp. 135 ◽  
Author(s):  
Norman E. Sharpless ◽  
Alberta E. Blair ◽  
Charles R. Maxwell
Keyword(s):  
Amino Acids ◽  
Ionizing Radiation ◽  
Aqueous Solutions ◽  
X Rays

Effects of x-rays on dilute aqueous solutions of amino acids

1956 ◽  
Vol 11 (4-5) ◽  
pp. 565-574 ◽  
Author(s):  
Judith Nosworthy ◽  
C.B. Allsopp
Keyword(s):  
Amino Acids ◽  
Aqueous Solutions ◽  
X Rays ◽  
Dilute Aqueous Solutions

The reaiation chemistry of aqueous solutions of [14C]Benzoic and [14C}Salicylic Acids

1958 ◽  
Vol 11 (2) ◽  
pp. 154 ◽  
Author(s):  
AM Downes
Keyword(s):  
Salicylic Acid ◽  
Ionizing Radiation ◽  
Benzoic Acid ◽  
Aqueous Solutions ◽  
Radioactive Tracer ◽  
Alkaline Solutions ◽  
X Rays ◽  
Tracer Techniques ◽  
Hydroxybenzoic Acids ◽  
G Value

Radioactive tracer techniques have been used to study the effect of ionizing radiation (60Co γ-radiation and 45 kV X-rays) on [14C]benzoic acid (both carboxyl- and uniformly-labelled) and on [carboxy-14C]salicylic acid in aerated aqueous solutions. �� The production of o-, m-, and p-hydroxybenzoic acids from benzoic acid (Loebl, Stein, and Weiss 1951) has been cord3rmed. The approximate initial G values for these products were : ortho, 0.74 ; meta, 0.42 ; para, 0.33. The ratio o : m : p was thus approximately 9 : 5 : 4 whereas Loebl, Stein, and Weiss found the corresponding ratio to be 5 : 2 : 10. Benzoic acid and sodium benzoate were also decarboxylated [G(CO2) : 0.73 � 0.03]. The extent of decarboxylation was independent of the initial concentration of benzoic acid in the range studied (0.5-7.0 X 10-3 M). The total reaction of the benzoic acid corresponded to a G value of approximately 2.6. Very little, if any, diphenyl was produced. The main non-volatile products from salicylic acid were 2,3- and 2,5-dihydroxy- benzoic acids which were obtained in the ratio 2,5 : 2,3 :: 1 : 1.6. The 2,4- and 2,6- isomers were not detected. Salicylic acid was also decarboxylated, G(CO2) being 1 53 � 0.07 in alkaline solutions. The above results are compared with other results relating to free-radical reactions. The possible use of the decarboxylation of sodium [carboxy-14C]benzoate as a sensitive dosimeter for ionizing radiation is suggested.

Imaging polymers, proteins and dna in aqueous solutions with the atomic force microscope

1989 ◽  
Vol 47 ◽  
pp. 32-33
Author(s):  
S.A.C. Gould ◽  
B. Drake ◽  
C.B. Prater ◽  
A.L. Weisenhorn ◽  
S.M. Lindsay ◽  
...  
Keyword(s):  
Amino Acids ◽  
Dna Sequencing ◽  
Aqueous Solutions ◽  
Atomic Force Microscope ◽  
Piezoelectric Crystal ◽  
Atomic Force ◽  
Structure Of Molecules ◽  
Optical Lever

The atomic force microscope (AFM) is an instrument that can be used to image many samples of interest in biology and medicine. Images of polymerized amino acids, polyalanine and polyphenylalanine demonstrate the potential of the AFM for revealing the structure of molecules. Images of the protein fibrinogen which agree with TEM images demonstrate that the AFM can provide topographical data on larger molecules. Finally, images of DNA suggest the AFM may soon provide an easier and faster technique for DNA sequencing.The AFM consists of a microfabricated SiO2 triangular shaped cantilever with a diamond tip affixed at the elbow to act as a probe. The sample is mounted on a electronically driven piezoelectric crystal. It is then placed in contact with the tip and scanned. The topography of the surface causes minute deflections in the 100 μm long cantilever which are detected using an optical lever.

scholarly journals Meta-studtite stability in aqueous solutions. Impact of HCO3−, H2O2 and ionizing radiation on dissolution and speciation

2021 ◽  
Author(s):  
Junyi Li ◽  
Zoltán Szabó ◽  
Mats Jonsson
Keyword(s):  
Aqueous Solution ◽  
Ionizing Radiation ◽  
Aqueous Solutions ◽  
Carbonate Complexes ◽  
C Nmr

Four different uranyl-(peroxide)-carbonate complexes were identified during studtite and meta-studtite dissolution in aqueous solution containing 10 mM HCO3− by 13C NMR.

scholarly journals Differential Effects of Gold Nanoparticles and Ionizing Radiation on Cell Motility between Primary Human Colonic and Melanocytic Cells and Their Cancerous Counterparts

2021 ◽  
Vol 22 (3) ◽  
pp. 1418
Author(s):  
Elham Shahhoseini ◽  
Masao Nakayama ◽  
Terrence J. Piva ◽  
Moshi Geso
Keyword(s):  
Gold Nanoparticles ◽  
Ionizing Radiation ◽  
Cancer Cells ◽  
Cell Lines ◽  
Colorectal Adenocarcinoma ◽  
X Rays ◽  
Cell Adherence ◽  
Cancerous Cell ◽  
Primary Colon ◽  
Radiation Induced

This study examined the effects of gold nanoparticles (AuNPs) and/or ionizing radiation (IR) on the viability and motility of human primary colon epithelial (CCD841) and colorectal adenocarcinoma (SW48) cells as well as human primary epidermal melanocytes (HEM) and melanoma (MM418-C1) cells. AuNPs up to 4 mM had no effect on the viability of these cell lines. The viability of the cancer cells was ~60% following exposure to 5 Gy. Exposure to 5 Gy X-rays or 1 mM AuNPs showed the migration of the cancer cells ~85% that of untreated controls, while co-treatment with AuNPs and IR decreased migration to ~60%. In the non-cancerous cell lines gap closure was enhanced by ~15% following 1 mM AuNPs or 5 Gy treatment, while for co-treatment it was ~22% greater than that for the untreated controls. AuNPs had no effect on cell re-adhesion, while IR enhanced only the re-adhesion of the cancer cell lines but not their non-cancerous counterparts. The addition of AuNPs did not enhance cell adherence. This different reaction to AuNPs and IR in the cancer and normal cells can be attributed to radiation-induced adhesiveness and metabolic differences between tumour cells and their non-cancerous counterparts.

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