scholarly journals Exercise-Induced Stress Response as an Adaptive Tolerance Strategy

1998 ◽  
Vol 106 ◽  
pp. 325 ◽  
Author(s):  
Joan Smith Sonneborn ◽  
Scott A. Barbee
Keyword(s):  
Stress Response ◽  
Tolerance Strategy ◽  
Induced Stress ◽  
Exercise Induced

Effect of SunGold TM Kiwifruit and Vitamin C Consumption on Ameliorating Exercise‐Induced Stress Response in Women

2021 ◽  
pp. 2001219
Author(s):  
Ajmol Ali ◽  
Sunali Mehta ◽  
Carlene Starck ◽  
Marie Wong ◽  
Wendy J. O'Brien ◽  
...  
Keyword(s):  
Stress Response ◽  
Vitamin C ◽  
Induced Stress ◽  
Exercise Induced

scholarly journals Efficacy of Nx4 to Reduce Plasma Cortisol and Gastrin Levels in Norwegian Sled Dogs During an Exercise Induced Stress Response: A Prospective, Randomized, Double Blinded, Placebo-Controlled Cohort Study

2021 ◽  
Vol 8 ◽  
Author(s):  
Alexandra Keller ◽  
Jana Conradi ◽  
Corinna Weber ◽  
Klaus Failing ◽  
Melanie Wergin
Keyword(s):  
Placebo Group ◽  
Stress Response ◽  
Plasma Cortisol ◽  
High Performance ◽  
Main Study ◽  
Plasma Gastrin ◽  
Induced Stress ◽  
Sled Dogs ◽  
Exercise Induced ◽  
Double Blinded

Introduction: An exercise induced stress response is commonly seen in high performance sled dogs, resulting in increased plasma cortisol. A stress induced rise of cortisol might result in increased prevalence of gastritis and gastric ulcers mediated by an increase of gastrin. Neurexan® (Nx4) is a medicinal product used for stress relief by reduction of cortisol. The aim of the study was to show that Nx4 reduces plasma cortisol and plasma gastrin in high performance sled dogs and to show tolerability of Nx4 in dogs.Material and Methods: First, a pilot study was done to validate the increase of cortisol by performance. The data from the pilot study was used for sample size estimation via an adapted power analysis as well as the identification of important variables. These were then used in the randomization procedure of the main study. Second, a prospective randomized, double blinded, placebo-controlled cohort study was conducted. The main study included 45 sled dogs, assigning 23 dogs to the Nx4 group, and 22 dogs to the placebo group, to analyze plasma cortisol and plasma gastrin at four time points: before, directly after and 30 and 120 min after performance.Results: For the main target variable, area under the curve (AUC) of plasma cortisol, a significantly lower adjusted mean value in the Nx4 group compared to the placebo group (p = 0.031) was found. Plasma gastrin was also significantly reduced in the Nx4 group 30 min after performance (p = 0.023), resulting in a significantly reduced plasma gastrin AUC in the Nx4 group compared to the placebo group (p = 0.049).Discussion: Within the limitation of the study, the results carry implications for the usefulness of Nx4 to reduce exercise induced plasma cortisol and gastrin levels. The reduction of the exercise induced stress response could help to improve the welfare of high-performance sled dogs. Since activation of the hypothalamic-pituitary-adrenal axis resulting in increased cortisol is similar for exercise induced stress and psychologic stress, the same might be true independent of the stressor, making Nx4 potentially useful in any stressful situation for dogs.

scholarly journals Cyclooxygenase inhibitors and the exercise-induced stress response

2006 ◽  
Vol 18 (1) ◽  
pp. 4 ◽  
Author(s):  
N Claassen ◽  
J Snyman ◽  
A Koorts ◽  
H Nolte ◽  
B Wagenaar ◽  
...  
Keyword(s):  
Single Dose ◽  
Stress Response ◽  
Sports Medicine ◽  
Temperature Response ◽  
Cyclooxygenase Inhibitors ◽  
Double Blind ◽  
Post Exercise ◽  
Induced Stress ◽  
Cyclooxygenase 1 ◽  
Exercise Induced

Objective. This study investigated the effects of single dosages of the non-steroidal anti-inflammatory drug (NSAID) naproxen, and of the coxib, rofecoxib, on the exercise-induced stress response. Design. Eight subjects (age 20.9 ± 1.1 years, weight 70.4 ± 3.9 kg, height 170.9 ± 6.7 cm, body surface area 1.82 ± 0.09 m2, body mass index 24.1 ± 1.3 kg.m-2) took part in a double-blind, drug-placebo, cross-over design study. The experimental procedures were performed on 3 occasions on each volunteer, i.e. once on placebo, once on naproxen (single dose of 1 000 mg) and once on rofecoxib (single dose of 50 mg). Results. Mean post-exercise cortisol values were significantly higher than pre-exercise values with the subjects on placebo (p = 0.0365) and rofecoxib (p = 0.0208), but not on naproxen (p = 0.0732). Post-exercise oral temperatures were significantly higher than pre-exercise temperature values on placebo (p = 0.0153) and rofecoxib (p = 0.0424), but not on naproxen (p = 0.5444). Conclusion. The results of this study suggest a role for cyclooxygenase-1 (COX-1) in the exercise-induced cortisol and temperature response to exercise. South African Journal of Sports Medicine Vol. 18 (1) 2006: pp. 4-8

scholarly journals Cyclooxygenase inhibitors and the exercise-induced stress response

2009 ◽  
Vol 18 (1) ◽  
pp. 4
Author(s):  
N Claassen ◽  
J Snyman ◽  
A Koorts ◽  
H Nolte ◽  
B Wagenaar ◽  
...  
Keyword(s):  
Single Dose ◽  
Stress Response ◽  
Sports Medicine ◽  
Temperature Response ◽  
Cyclooxygenase Inhibitors ◽  
Double Blind ◽  
Post Exercise ◽  
Induced Stress ◽  
Cyclooxygenase 1 ◽  
Exercise Induced

Objective. This study investigated the effects of single dosages of the non-steroidal anti-inflammatory drug (NSAID) naproxen, and of the coxib, rofecoxib, on the exercise-induced stress response. Design. Eight subjects (age 20.9 ± 1.1 years, weight 70.4 ± 3.9 kg, height 170.9 ± 6.7 cm, body surface area 1.82 ± 0.09 m2, body mass index 24.1 ± 1.3 kg.m-2) took part in a double-blind, drug-placebo, cross-over design study. The experimental procedures were performed on 3 occasions on each volunteer, i.e. once on placebo, once on naproxen (single dose of 1 000 mg) and once on rofecoxib (single dose of 50 mg). Results. Mean post-exercise cortisol values were significantly higher than pre-exercise values with the subjects on placebo (p = 0.0365) and rofecoxib (p = 0.0208), but not on naproxen (p = 0.0732). Post-exercise oral temperatures were significantly higher than pre-exercise temperature values on placebo (p = 0.0153) and rofecoxib (p = 0.0424), but not on naproxen (p = 0.5444). Conclusion. The results of this study suggest a role for cyclooxygenase-1 (COX-1) in the exercise-induced cortisol and temperature response to exercise. South African Journal of Sports Medicine Vol. 18 (1) 2006: pp. 4-8

The Exercise-Induced Stress Response of Skeletal Muscle, with Specific Emphasis on Humans

2009 ◽  
Vol 39 (8) ◽  
pp. 643-662 ◽  
Author(s):  
James P. Morton ◽  
Anna C. Kayani ◽  
Anne McArdle ◽  
Barry Drust
Keyword(s):  
Skeletal Muscle ◽  
Stress Response ◽  
Induced Stress ◽  
Exercise Induced

The exercise-induced stress response in skeletal muscle: failure during aging

2008 ◽  
Vol 33 (5) ◽  
pp. 1033-1041 ◽  
Author(s):  
Anna C. Kayani ◽  
James P. Morton ◽  
Anne McArdle
Keyword(s):  
Skeletal Muscle ◽  
Stress Response ◽  
Contractile Activity ◽  
Older Individuals ◽  
Adult Skeletal Muscle ◽  
Induced Stress ◽  
Exercise Induced ◽  
Shock Proteins ◽  
Exercise And Training ◽  
And Training

Mammalian adult skeletal muscle adapts to the stress of contractile activity with increased gene expression by yielding a family of highly conserved cytoprotective proteins known as heat shock proteins (HSPs). Although the exercise-induced stress response of both animal and human skeletal muscle is now well documented, the precise mechanisms underlying this adaptation remain unclear. The induction of HSPs after exercise is severely blunted in the muscle of older individuals. This review focuses on the effects of different forms of exercise and training on the induction of HSPs in the muscles of adult individuals, and examines the proposed mechanisms underlying this adaptation. Furthermore, the functional effect of the inability of the muscles of older individuals to adapt in this way is discussed, together with the proposed mechanisms underlying this maladaptation.

Loading-Induced Stress Response in the Intervertebral Disc

2014 ◽  
Vol 4 (1_suppl) ◽  
pp. s-0034-1376604-s-0034-1376604
Author(s):  
W. H. Chooi ◽  
S. C. Chan ◽  
B. Gantenbein-Ritter ◽  
B. P. Chan
Keyword(s):  
Stress Response ◽  
Intervertebral Disc ◽  
Induced Stress
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