Reconstruction of the Chondriome of the Amastigote Form of Trypanosoma cruzi

1989 ◽  
Vol 75 (4) ◽  
pp. 649 ◽  
Author(s):  
Lisa B. Newberry ◽  
Jerome J. Paulin
Keyword(s):  
Trypanosoma Cruzi ◽  
Amastigote Form

scholarly journals 2α-Acetoxy-15-acetylartemisiifolin, a new Anti-trypanosomal Sesquiterpene Lactone from Mikania guaco

2017 ◽  
Vol 12 (5) ◽  
pp. 1934578X1701200
Author(s):  
Ahmed A. Hussein ◽  
Luz Romero ◽  
Jose Luis López-Pérez ◽  
Mahabir P. Gupta
Keyword(s):  
Mass Spectrometry ◽  
Trypanosoma Cruzi ◽  
Sesquiterpene Lactone ◽  
Chemical Structure ◽  
Methanol Extract ◽  
Amastigote Form ◽  
Bioassay Guided Fractionation ◽  
Nmr Techniques

Mikania guaco Bonpl. methanol extract showed an interesting activity against Trypanosoma cruzi with an IC50 of 4 μg/mL. Bioassay-guided fractionation of the methanol extract resulted in the isolation of a new sesquiterpene lactone, 2α-acetoxy, 15-acetylartemisiifolin (1), which was shown to be active (IC50 = 25 μM) against the amastigote form of T. cruzi,. The chemical structure of 1 was elucidated using 2-D NMR techniques and mass spectrometry.

Protective effect of Trypanosoma rangeli against infections with a highly virulent strain of Trypanosoma cruzi

1997 ◽  
Vol 2 (5) ◽  
pp. 482-487 ◽  
Author(s):  
Claudio Zuniga ◽  
Teresa Palau ◽  
Pilar Penin ◽  
Carlos Gamallo ◽  
Jose Antonio de Diego
Keyword(s):  
Trypanosoma Cruzi ◽  
Protective Effect ◽  
Virulent Strain ◽  
Trypanosoma Rangeli ◽  
Highly Virulent

Unusual dimeric flavonoids from Arrabidaea brachypoda with very significant in vitro and in vivo anti-Trypanosoma cruzi activity

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
C Quitino-da-Rocha ◽  
E Ferreira-Queiroz ◽  
C Santana-Meira ◽  
DR Magalhães-Moreira ◽  
M Botelho-Pereira-Soares ◽  
...  
Keyword(s):  
Trypanosoma Cruzi
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