Graffilla pugetensis n. sp. (Order Neorhabdocoela: Graffillidae), a Parasite in the Pericardial Cavity of the Bent-Nose Clam, Macoma nasuta (Conrad, 1837)

1986 ◽  
Vol 72 (5) ◽  
pp. 748
Author(s):  
Stewart C. Schell
Keyword(s):  
Pericardial Cavity ◽  
Macoma Nasuta

scholarly journals Prevention of postoperative intrapericardial adhesion by dextrin hydrogel

2021 ◽  
Author(s):  
Satoshi Kikusaki ◽  
Kazuyoshi Takagi ◽  
Takahiro Shojima ◽  
Kosuke Saku ◽  
Tomofumi Fukuda ◽  
...  
Keyword(s):  
Crystal Violet ◽  
Proliferative Response ◽  
Sham Group ◽  
Cardiac Tissue ◽  
Crystal Violet Staining ◽  
Pericardial Cavity ◽  
Uptake Assay ◽  
Surgically Induced ◽  
Observation Period

Abstract Objective Postoperative intrapericardial adhesion increases the risk of complications in patients undergoing reoperation. We investigated the effect of a bioabsorbable dextrin hydrogel (DHG) on the formation of intrapericardial adhesions. Methods Intrapericardial adhesion was surgically induced in Japanese white rabbits with DHG treatment (Adh + DHG) or without DHG treatment (Adh). The sham group was not treated with DHG and intrapericardial adhesion was not induced. The extent of intrapericardial adhesion was assessed by adhesion scoring and crystal violet staining of the pericardial cavity. Bromodeoxyuridine (BrdU) uptake assay was performed to assess the proliferative response to the injury in the tissue beneath the intrapericardial adhesion. Results The Adh + DHG group showed looser intrapericardial adhesions compared to the Adh group. The adhesion area of the Adh + DHG group was 4.6 ± 2.2%, whereas that of the Adh group was 32.6 ± 6.4% at the end of the 28-day observation period (p < 0.01). The induction of intrapericardial adhesion resulted in a proliferative response mainly in the cardiac tissue just beneath the adhesion. There were 48.6 ± 10.7 cells/0.1 mm2 BrdU-positive cells in the Adh + DHG group and 135.7 ± 23.8 cells/0.1 mm2 BrdU-positive cells in the Adh group on day 28 (p < 0.05). Conclusion These findings indicate that DHG effectively prevented intrapericardial adhesion in this model.

scholarly journals MRI of malignant peripheral nerve sheath tumour in pericardial cavity

2018 ◽  
pp. bcr-2018-224481
Author(s):  
Ryoma Endo ◽  
Tomoko Tomioka ◽  
Ken Okada ◽  
Kanichi Inoue
Keyword(s):  
Peripheral Nerve ◽  
Nerve Sheath Tumour ◽  
Pericardial Cavity ◽  
Nerve Sheath ◽  
Peripheral Nerve Sheath Tumour

scholarly journals Hepatic hydatid cyst rupturing into pericardial cavity

Heart ◽  
2006 ◽  
Vol 92 (10) ◽  
pp. 1536-1536 ◽  
Author(s):  
F Martin-Herrero
Keyword(s):  
Hydatid Cyst ◽  
Hepatic Hydatid Cyst ◽  
Pericardial Cavity ◽  
Hepatic Hydatid

A radioautographic analysis of the migration and fate of cells derived from the occipital somites in the chick embryo with specific reference to the development of the hypoglossal musculature

Development ◽  
1970 ◽  
Vol 24 (3) ◽  
pp. 455-466
Author(s):  
R. D. Hazelton
Keyword(s):  
Chick Embryo ◽  
Dorsal Surface ◽  
Lateral Position ◽  
Migration Pattern ◽  
Specific Reference ◽  
Specific Marker ◽  
Differential Growth ◽  
Pericardial Cavity ◽  
And Migration ◽  
Pharyngeal Area

The migration pattern and fate of cells of the occipital somites and overlying ectoderm have been described for the chick embryo with particular reference to the development of the hypoglossal musculature. Tritium-labelled thymidine (0·5–10 µCi per egg) was used as a cell-specific marker. Occipital somites (2–5) with overlying ectoderm were transplanted orthotopically from labelled donor embryos to unlabelled host embryos (Hamburger & Hamilton, stage 9–10). The embryos were incubated, for varying lengths of time (24 h-5 days), sacrificed, sectioned and the migration pattern and fate of the labelled cells determined radioautographically. It appears that the hypoglossal as well as other hypopharyngeal musculature originates from the occipital somites. The mesodermal migration pattern extended from the occipital somite region in a ventroposterior direction to the dorsal surface of the pericardial cavity posterior to the expanded portion of the pharynx. At this position a so-called hypoglossal cord formed on each side which ran anteriorly to the level of the second pharyngeal pouch where it turned medially and together with the cord from the other side entered the pharyngeal area of the embryo. This material apparently forms the intrinsic musculature of the tongue. The mesodermal movements are attributed to differential growth movements of the areas concerned as well as to active cell mutiplication and migration. Selective embryonic neuronal staining was undertaken to study the relationship between the migrating hypoglossal cord and nerve. The cord preceded the nerve in its migration. There is an occipital somitic contribution to the primitive meninx, to the endothelial walls of developing blood vessels, possibly to microglial cells and to the cartilage surrounding the notocord. The occipital ectoderm expands dorso-anteriorly and ventro-laterally. In the ventro-lateral position as contact is made with the pharyngeal endoderm a placode is formed which contributes cells to the nodose ganglion of the tenth cranial nerve. There is no other contribution of the ectoderm to the underlying tissues.

Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration

2021 ◽  
Author(s):  
Marlly Guarin ◽  
Ruben Faelens ◽  
Arianna Giusti ◽  
Noémie De Croze ◽  
Marc Léonard ◽  
...  
Keyword(s):  
Molecular Descriptor ◽  
False Negative ◽  
Whole Body ◽  
Pericardial Cavity ◽  
Routes Of Administration ◽  
Relationship Analysis ◽  
Negative Results ◽  
False Negative Results ◽  
Parameter Values ◽  
Fluorescent Compounds

Abstract Zebrafish (Danio rerio) is increasingly used to assess the pharmacological activity and toxicity of compounds. The spatiotemporal distribution of seven fluorescent alkyne compounds was examined during 48 h after immersion (10 µM) or microinjection (2 mg/kg) in the pericardial cavity (PC), intraperitoneally (IP) and yolk sac (IY) of 3 dpf zebrafish eleuthero-embryos. By modelling the fluorescence of whole-body contours present in fluorescence images, the main pharmacokinetic (PK) parameter values of the compounds were determined. It was demonstrated that especially in case of short incubations (1-3h) immersion can result in limited intrabody exposure to compounds. In this case, PC and IP microinjections represent excellent alternatives. Significantly, IY microinjections did not result in a suitable intrabody distribution of the compounds. Performing a QSPkR (quantitative structure-pharmacokinetic relationship) analysis, LogD was identified as the only molecular descriptor that explains the final uptake of the selected compounds. It was also shown that combined administration of compounds (immersion and microinjection) provides a more stable intrabody exposure, at least in case of a prolonged immersion and compounds with LogD value > 1. These results will help reduce the risk of false negative results and can offer an invaluable input for future translational research and safety assessment applications.

scholarly journals Postoperative Pericardial Adhesion Prevention Using Collagen Membrane in Pigs: A Pilot Study

2017 ◽  
Vol 9 ◽  
pp. 117906521772090 ◽  
Author(s):  
Noppon Taksaudom ◽  
Metus Ketwong ◽  
Nirush Lertprasertsuke ◽  
Aphisek Kongkaew
Keyword(s):  
Heart Surgery ◽  
Open Heart Surgery ◽  
The Body ◽  
Adhesion Prevention ◽  
Control Group ◽  
Collagen Membrane ◽  
Pericardial Cavity ◽  
True Value ◽  
Collagen Membranes ◽  
Experimental Group

Objective: The operating procedure of a resternotomy in open-heart surgery is a complicated procedure with potentially problematic outcomes partly due to potential adhesions in the pericardial cavity and retrosternal space. Use of a collagen membrane has shown encouraging results in adhesion prevention in several regions of the body. This study was designed to evaluate the effectiveness of the use of this collagen membrane in the prevention of pericardial adhesions. Materials and methods: A total of 12 pigs were divided randomly into 2 groups: an experimental group in which collagen membranes were used and a control group. After sternotomy and an anterior pericardiectomy, the epicardial surface was exposed to room air and irrigated with saline, and an epicardial abrasion was performed using a sponge. The pericardial defect was repaired using a collagen membrane in the experimental group or left uncovered in the control group. After 8 to 12 weeks, the pigs were killed, and a resternotomy was performed by a single-blinded surgeon enabling the evaluation of adhesions. The heart was then removed and sent for microscopic assessment conducted by a single-blinded pathologist. Results: The resternotomy operations performed using a collagen membrane demonstrated a nonstatistically significant trend of fewer macroscopic and microscopic adhesions in all regions ( P > .05), particularly in the retrosternal and defect regions. Conclusions: This study showed nonstatistically significant differences between the outcomes in the collagen membrane group and the control group in both macroscopic and microscopic adhesion prevention. Due to the many limitations in animal study design, further studies in human models will be needed before the true value of this procedure can be evaluated.

scholarly journals ХИРУРГИЯ ЭКССУДАТИВНЫХ ПЕРИКАРДИТОВ

2019 ◽  
pp. 14-19
Author(s):  
Лигоненко А. В.
Keyword(s):  
Pericardial Effusion ◽  
Diagnostic Methods ◽  
Common Disease ◽  
Clinical Progression ◽  
Surgical Interventions ◽  
Pericardial Cavity ◽  
Differential Approach ◽  
Literary Sources ◽  
Choice Of Treatment

In the article are presented modern approaches to diagnostics, etiological search and methods of surgical correction of pericardial effusion (PE) of different etiology. PE being the most common disease of the pericardium, often has a secondary nature. The overview of modern literature data is presented about terminology and classification of PE, the possibility of etiological search for the cause of effusion in the pericardial cavity, the main diagnostic methods, as well as the main tasks and methods of pericardial surgical interventions and its indications. Based on the analysis of literary sources, we can conclude that the consensus on the clinical and nosological structure, effectiveness and necessity of using various tests and interventions, clinical progression, epidemiology, prognosis and the reasons for the unsatisfactory results of treated PE is actually absent. Our analysis indicates the absence of a systematic and differential approach to choice of treatment tactics.

The Fate of Thorium Dioxide Injected into the Pedal Sinus of Bullia (Gastropoda: Prosobranchiata)

1965 ◽  
Vol 42 (3) ◽  
pp. 509-519
Author(s):  
A. C. BROWN ◽  
ROSALIND J. BROWN
Keyword(s):  
Mitotic Index ◽  
Sandy Beach ◽  
Mantle Cavity ◽  
The Body ◽  
Thorium Dioxide ◽  
Pericardial Cavity ◽  
Main Pathway ◽  
Heart Wall

1. The removal and ultimate disposal of foreign particles injected into the haemolymph of the sandy-beach snail, Bullia, has been studied by using the radio-opaque dye Thorotrast. 2. Particles are removed by phagocytic haemocytes which migrate by various routes to the outside of the body. The main pathway is through the heart wall into the pericardial cavity and via the renopericardial canal into the lumen of the kidney, from which the cells escape into the mantle cavity. 3. The injection of foreign particles stimulates a marked increase in the haemocyte population and also in the mitotic index. 4. The final discussion integrates the available evidence and a comparison is made between Bullia and other molluscs. The origin of the macrophages is discussed.

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