The Resistance of Egg-Laying Ducks to Infection by the Malaria Parasite Plasmodium lophurae

1948 ◽  
Vol 34 (5) ◽  
pp. 389 ◽  
Author(s):  
William Trager
Keyword(s):  
Malaria Parasite ◽  
Egg Laying ◽  
Plasmodium Lophurae ◽  
Parasite Plasmodium

scholarly journals Primary structure and genomic organization of the histidine-rich protein of the malaria parasite Plasmodium lophurae

Nature ◽  
1985 ◽  
Vol 317 (6037) ◽  
pp. 558-558 ◽  
Author(s):  
J. V. Ravetch ◽  
R. Feder ◽  
A. Pavlovec ◽  
G. Blobel
Keyword(s):  
Primary Structure ◽  
Malaria Parasite ◽  
Genomic Organization ◽  
Plasmodium Lophurae ◽  
Parasite Plasmodium

scholarly journals FACTORS IN PLASMA CONCERNED IN NATURAL RESISTANCE TO AN AVIAN MALARIA PARASITE (PLASMODIUM LOPHURAE)

1950 ◽  
Vol 91 (4) ◽  
pp. 365-379 ◽  
Author(s):  
William Trager ◽  
R. Barclay McGhee
Keyword(s):  
Malaria Parasite ◽  
Avian Malaria ◽  
Natural Resistance ◽  
Relative Resistance ◽  
Active Materials ◽  
Adult Chicken ◽  
Active Ovary ◽  
Plasmodium Lophurae ◽  
Parasite Plasmodium ◽  
Avian Malaria Parasite

The plasma of adult chickens, when injected into young chicks or chick embryos infected with Plasmodium lophurae, lessened the parasitemia. The substances responsible for this effect were inactivated or removed by the heating of adult chicken plasma for ½ hour at 65°C., followed by centrifugation to remove the coagulated material; but they were not affected by heating for ½ hour at 56°C. The active materials were present in the euglobulin fraction of hen plasma. In similar experiments with ducks, the plasma from each of a series of adult ducks was tested for its effect on the course of infection in young ducklings. The adult ducks were then inoculated with a large dose of parasites. There was a positive correlation between the effectiveness of a plasma in lessening the parasitemia of ducklings treated with it and the resistance on infection exhibited by the duck from which the plasma had been obtained. More than half of the adult female ducks with an active ovary which were tested, but only one of the males, had effective plasmas and also showed relative resistance to the infection.

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