Cadmium Poisoning from Silver Soldering

doi:10.2307/3178926

Mixed ligand chelate therapy for plutonium and cadmium poisoning

Nature ◽

10.1038/281406b0 ◽

1979 ◽

Vol 281 (5730) ◽

pp. 406-406 ◽

Cited By ~ 12

Author(s):

JACK SCHUBERT

Keyword(s):

Mixed Ligand ◽

Cadmium Poisoning ◽

Chelate Therapy

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Isolation of a new low molecular weight β2-globulin from urine of a worker with chronic cadmium poisoning

Biochemical and Biophysical Research Communications ◽

10.1016/0006-291x(80)91110-9 ◽

1980 ◽

Vol 93 (2) ◽

pp. 535-543 ◽

Cited By ~ 13

Author(s):

Alfred M. Bernard ◽

Robert R. Lauwerys ◽

Vincenzo Starace ◽

Pierre L. Masson

Keyword(s):

Molecular Weight ◽

Low Molecular Weight ◽

Cadmium Poisoning

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ANALYSIS OF MT2A AND MT3 GENE EXPRESSION IN RAT'S LIVER AND KIDNEY IN RESPONSE TO CADMIUM CHLORIDE POISONING

Токсикологический вестник ◽

10.36946/0869-7922-2020-6-38-42 ◽

2021 ◽

pp. 38-42

Author(s):

M. M. Ziatdinova ◽

T. G. Yakupova ◽

Ya. V. Valova ◽

G. F. Mukhammadieva ◽

D. O. Karimov ◽

...

Keyword(s):

Gene Expression ◽

Rat Liver ◽

Cadmium Chloride ◽

Transcriptional Activity ◽

Female Rats ◽

Expression Level ◽

Cadmium Poisoning ◽

Liver And Kidney ◽

Dose Dependent ◽

Higher Doses

The aim of this study was to investigate the expression of metallothionein genes in the liver and kidneys of rats with acute cadmium poisoning.Simulation of poisoning with cadmium chloride was carried out on white outbred female rats, divided into 4 groups depending on the dose of the injected toxicant. RNA samples isolated from rat liver and kidneys were used as research materials.The multiplicity of expression of the MT3 gene in the kidneys increased at the lowest dose of CdCl2 , which was used in this experiment (0.029 mg / kg); with increasing dosage, the expression level decreased, but not lower than the control values. Analysis of the expression of the same gene in the liver showed a tendency towards a decrease in the content of transcripts with increasing dose. The frequency of expression of the MT2A gene at higher doses of CdCl2 increased both in the liver and in the kidneys.In the present work, statistically significant dose-dependent changes in the expression multiplicity of metallothionein genes were detected 24 hours after CdCl2 administration. The revealed differences in the level of transcriptional activity of metallothionein genes require further investigation, since there are probably differences in the level of gene expression at earlier and later periods of toxicant action.

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