Blood Groups (ABO, M-N and Rh), ABH Secretion, Sickle-Cell, P.T.C. Taste, and Colour Blindness in the Mahar of Nagpur

1961 ◽  
Vol 91 (2) ◽  
pp. 345 ◽  
Author(s):  
S. R. Das ◽  
N. Kumar ◽  
P. N. Bhatacharjee ◽  
D. B. Sastry
Keyword(s):  
Sickle Cell ◽  
Blood Groups ◽  
Colour Blindness

scholarly journals A Cross Sectional Study of Association of HLA typing with Haemoglobin Level in Sickle Cell Anaemia

2021 ◽  
pp. 523-531
Author(s):  
Raed Alserihi ◽  
Saeed Kabrah ◽  
Hadeel Alsadoun
Keyword(s):  
Sickle Cell Disease ◽  
Blood Transfusion ◽  
Blood Cell ◽  
Sickle Cell ◽  
Blood Groups ◽  
Hemoglobin Level ◽  
Hla Typing ◽  
Control Group ◽  
Allelic Association ◽  
Cell Disease

Background: Sickle-cell Disease (SCD) is the most common blood cell disorder affecting millions of people. In severe cases, regular blood transfusion is an essential practice to relieve clinical symptoms. However, since regular blood transfusion can lead to alloimmunization to foreign human leukocyte antigens (HLA), this may result in severe anemia due to red blood cell destruction. Therefore, this study aimed to determine the association between the hemoglobin level and the presence of HLA genotypes among Sickle Cell Anemia patients.  Methodology: A total of 64 SCD patients and 21 healthy donors seen at King Abdulaziz hospital between November 2019 and February 2021 were recruited for this study. Demographic data including ABO/Rhesus blood groups, hemoglobin concentration, were among the clinical information obtained. HLA genotyping was performed using Polymerase Chain Reaction-Sequence Specific Oligonucleotide (PCR-SSO). The data were cleaned using the Microsoft Excel and analysed using the statistical packages for Social Sciences (SPSS) version 24. Results: The incidence of SCD is not strictly gender-related because of its transmission as an autosomal recessive disorder. Sixty-four individuals (33 females; 31 males) having SCD were analyzed. O blood group recorded the highest prevalence compared to other ABO blood groups in SCD patients. After analysing allelic association, HLA-A*02 was more frequent in SCD patients compared to control. After further allelic combination analysis of patients and compared with the control group, HLA-DQB1*02 was majorly involved in overexpression and decreasing hemoglobin level and significantly different among control and experimental groups. Conclusion: Rhesus-positive blood types were more associated with the SCA. HLA- type II alleles could influence the clinical course of sickle cell disease and HLA-DQB1*02 was significantly different among SCD group and control individuals, which signifies the concept that the allele was overexpressed among patients resulting in low Hb level.

SICKLE-CELL TRAIT AND BLOOD-GROUPS IN GREECE

The Lancet ◽  
1953 ◽  
Vol 262 (6792) ◽  
pp. 909-911 ◽  
Author(s):  
C Choremis ◽  
ElizabethW Ikin ◽  
H Lehmann ◽  
A.E Mourant ◽  
Leda Zannos
Keyword(s):  
Sickle Cell ◽  
Sickle Cell Trait ◽  
Blood Groups

scholarly journals New linkage data for the X-linked types of muscular dystrophy and G6PD variants, colour blindness, and Xg blood groups

1974 ◽  
Vol 11 (4) ◽  
pp. 321-327 ◽  
Author(s):  
M. Zatz ◽  
S. B. Itskan ◽  
R. Sanger ◽  
O. Frota-Pessoa ◽  
P. H. Saldanha
Keyword(s):  
Muscular Dystrophy ◽  
Blood Groups ◽  
Linkage Data ◽  
Colour Blindness

DNA‐based typing of blood groups for the management of multiply‐transfused sickle cell disease patients

Transfusion ◽  
2002 ◽  
Vol 42 (2) ◽  
pp. 232-238 ◽  
Author(s):  
Lilian Castilho ◽  
Maria Rios ◽  
Celso Bianco ◽  
Jordão Pellegrino ◽  
Fernando L. Alberto ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Blood Groups ◽  
Cell Disease

ABO Blood Groups and Sickle-cell Trait Investigations in Madhya Pradesh Indore District (Central India)

1966 ◽  
Vol 15 (4) ◽  
pp. 404-408 ◽  
Author(s):  
Narendra Kumar
Keyword(s):  
Sickle Cell ◽  
Sickle Cell Trait ◽  
Central India ◽  
Blood Groups ◽  
Madhya Pradesh ◽  
Abo Blood Groups ◽  
Blood Samples ◽  
Mixed Sample ◽  
Pooled Data

SummaryBlood samples from five hundred and ninety five individuals belonging to Indore district of west Madhya Pradesh were tested for ABO blood groups, and two hundred and ninety three of them were tested for the sickle-cell trait.The investigated groups include: the Kadve Kulmi, the Khati, the Rami Mali, the Balai, the Bhil and a mixed sample of various castes. The aforesaid groups, within the district, are found to be homogeneous, as far as the ABO blood groups distributions are concerned. Frequencies for the O, A and B genes have been found to be 0.5251, 0.1587 and 0.3162, respectively, in the pooled data.Sickle-cell trait has been detected in the Balai, the Charmakar or Chamar and the Bhil.

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