Immunological Identification of Small-Mammal Proteins on Aboriginal Milling Equipment

1991 ◽  
Vol 56 (4) ◽  
pp. 659-666 ◽  
Author(s):  
Robert M. Yohe ◽  
Margaret E. Newman ◽  
Joan S. Schneider

Ethnographic accounts of animal pulverization using stone grinding implements have led archaeologists to believe that this same behavior took place in the past. This important subsistence activity can now be confirmed through the immunological analysis of archaeological materials. Small-mammal blood-protein residue has been identified immunologically for the first time on milling equipment from two archaeological sites in southern California. Immunoprotein trace analysis has the potential for a wide range of applications in the study of prehistory.

2019 ◽  
Vol 11 (7) ◽  
pp. 1972 ◽  
Author(s):  
Ioannis Liritzis ◽  
Elena Korka

The interdisciplinary field of archaeometry covers a wide range of subject categories and disciplines in relation to science and humanities. It is a well-established academic field of study and accredited part of higher education. Since its inception, the nomenclature designation of archaeometry signifies the appropriate methodology applied to archaeological materials and questions emerging from this field, regarding monuments, artifacts, and the reconstruction and management of landscape bearing cultural assets. The measurements of tangible culture denote significant information, such as chronology, authenticity, technology, characterization, provenance, discovering buried antiquities, ancient-day life activities, and three-dimensional (3D) reconstructions and modelling; furthermore, proxy data collected from environmental dynamic non-liner perturbations, which link local ecosystems with dwellings, are gathered by academia to study the past. The traditional rooting signifies the cultural legacies of people, which define the human desire and the confidence of memory and future trends. Beyond the mere study of the past, archaeometry’s role increasingly proves affinity to prosperity, if properly managed. The major archaeometrical contributions in cultural heritage and archaeology in general are reviewed herein, and we present the policies that could develop archaeometrical data into a sustainable stage of local, regional, and national economic development. Τhe United Nations Educational, Scientific, and Cultural Organization (UNESCO) conventions for the documentation and protection of cultural heritage via new technologies and archaeometry are reviewed and connected to development strategies and sustainable development goals.


Author(s):  
Nikolay N. Seregin ◽  
Vladimir V. Tishin ◽  
Vadim V. Serov

The article is dedicated to the publication of a unique find that is a coin-shaped indication from the early medieval burial complex in Tuekta (Central Altai) and an attempt of its comprehensive analysis. Excavations of the archaeological site were carried out in the 1930s during the work of the Sayan-Altai expedition led by S.V. Kiselev, however, since then, the metioned find has not attracted the attention of researchers. The article presents a detailed description of the coin-shaped indication and the analysis of the applied images, it is there also given the characteristic of the archaeological context of the discovery of the object and discuss the possibility of reading fixed signs. As a result, it is presented an attempt to interpret the product in a specific historical and cultural context taking into account the materials received over the past decades. It should be noted the absence of identical archaeological finds in the numismatic collections. At the same time, an analysis of the details of the image on the coin-shaped indication made it possible to outline a wide range of analogies demonstrating the complex processes of cultural contacts in large territories of Eurasia over a long chronological period. The authors came to the conclusion that the analysed product, as well as other like finds from the archaeological sites of the Türks of Inner Asia, to be a kind of “social markers”, demonstrating their owners’ belonging to the elite strata of the nomadic society and, possibly, reflect their specific authority. The proposed interpretation of such things, given their scarcity, as well as the context of discovery not being obvious, seems debatable and, of course, requires the emergence of new data as a result of further archaeological research


2021 ◽  
Author(s):  
Rebecca Probert

The Marriage Act 1836 established the foundations of modern marriage law, allowing couples to marry in register offices and non-Anglican places of worship for the first time. Rebecca Probert draws on an exceptionally wide range of primary sources to provide the first detailed examination of marriage legislation, social practice, and their mutual interplay, from 1836 through to the unanticipated demands of the 2020 coronavirus pandemic. She analyses how and why the law has evolved, closely interrogating the parliamentary and societal debates behind legislation. She demonstrates how people have chosen to marry and how those choices have changed, and evaluates how far the law has been help or hindrance in enabling couples to marry in ways that reflect their beliefs, be they religious or secular. In an era of individual choice and multiculturalism, Tying the Knot sign posts possible ways in which future legislators might avoid the pitfalls of the past.


Author(s):  
Yana Hrynko

The purpose of the article is to analyze the role and place of “museum of conscience” in modern politics of memory and cultural space. The methodology is based on a comprehensive study of a wide range of museum expositions (interviews, reports, museum projects, reviews of museum collections, etc.) and generalization of the obtained material to identify current trends in the development of "museums of conscience" in the context of memory culture. Scientific novelty. On the example of specific museum research institutions (the Sixth District Museum in Cape Town, the Holocaust Memorial Museum (Washington, USA), the Museum of Military Childhood in Sarajevo, etc.) for the first time in Ukrainian historiography, their contribution to the process of deeper study of crimes of the past and its reflection in modern politics of memory and cultural space is analyzed. Conclusions: Places of conscience are museums, memorials, and other historical places, which aim not only to preserve memory but also to stimulate people’s conscience. While working with a visitor, they prefer forms that contribute to the involvement of a visitor in discussion and dialogue. The museum exhibit serves as a safe place to discuss sharp issues and reconcile conflicting parties in society. The museum collection and the results of its research are distributed in order to stimulate the human conscience. The task of the museums is not only to preserve the memory about the crimes of the past but also to provide an opportunity for a visitor to establish a connection between this past and today’s struggle for human rights.


Heritage ◽  
2021 ◽  
Vol 4 (2) ◽  
pp. 710-724
Author(s):  
Bruno Fanini ◽  
Daniele Ferdani ◽  
Emanuel Demetrescu

Today, Web3D technologies and the rise of new standards, combined with faster browsers and better hardware integration, allow the creation of engaging and interactive web applications that target the field of cultural heritage. Functional, accessible, and expressive approaches to discovering the past starting from the present (or vice-versa) are generally a strong requirement. Cultural heritage artifacts, decorated walls, etc. can be considered as palimpsests with a stratification of different actions over time (modifications, restorations, or even reconstruction of the original artifact). The details of such an articulated cultural record can be difficult to distinguish and communicate visually, while entire archaeological sites often exhibit profound changes in terms of shape and function due to human activities over time. The web offers an incredible opportunity to present and communicate enriched 3D content using common web browsers, although it raises additional challenges. We present an interactive 4D technique called “Temporal Lensing”, which is suitable for online multi-temporal virtual environments and offers an expressive, accessible, and effective way to locally peek into the past (or into the future) by targeting interactive Web3D applications, including those leveraging recent standards, such as WebXR (immersive VR on the web). This technique extends previous approaches and presents different contributions, including (1) a volumetric, temporal, and interactive lens approach; (2) complete decoupling of the involved 3D representations from the runtime perspective; (3) a wide range applications in terms of size (from small artifacts to entire archaeological sites); (4) cross-device scalability of the interaction model (mobile devices, multi-touch screens, kiosks, and immersive VR); and (5) simplicity of use. We implemented and developed the described technique on top of an open-source framework for interactive 3D presentation of CH content on the web. We show and discuss applications and results related to three case studies, as well as integrations of the temporal lensing with different input interfaces for dynamically interacting with its parameters. We also assessed the technique within a public event where a remote web application was deployed on tablets and smartphones, without any installation required by visitors. We discuss the implications of temporal lensing, its scalability from small to large virtual contexts, and its versatility for a wide range of interactive 3D applications.


2018 ◽  
Vol 20 (5) ◽  
pp. 637-640
Author(s):  
Michael Vallejo-Urrego ◽  
Alejandra M. Parra-Morales ◽  
Adriana Gonzalez

Objectives Hypoparathyroidism, sensorineural deafness and renal disease (HDR) syndrome, also known as Barakat syndrome, is an autosomal dominant transmission hereditary disease with a wide range of penetrance and expressivity. Haploinsufficiency of the GATA3 two finger zinc transcription factor is believed to be its cause. This is the first time this orphan disease is reported in Latin America, so the publishing of this report is expected to raise awareness on these types of syndrome, that are usually underdiagnosed in our region, which in turn causes an increase in the years lost to disability (YLDs) rates, as well as higher costs to be assumed by public health systems.Methods A 36-year-old Colombian woman diagnosed with parathyroid gland agenesis was referred from the Endocrinology Service to the Outpatient Service. According to her medical record, in the past she had developed hypocalcaemia, left renal agenesis, hypoparathyroidism, bicornate uterus and sensorineural hearing loss. Through a genetic analysis a pathological mutation on the short arm of the GATA 3 gen (c.404dupC, p Ala136 GlyfsTER 167) was confirmed, which led to a HDR syndrome diagnosis.Discussion This case proves that there is a possibility that mutations described in other continents may be developed by individuals from our region. Regardless of ethnicity, Barakat syndrome should be considered as a possible diagnosis in patients presenting the typical triad that has been described for this condition, since there could be underdiagnosis of this disease in Latin-America due to the lack of knowledge on this condition in said region, and that genetic counseling in these patients is of great importance for the implications of the syndrome in future generations.


1994 ◽  
Vol 42 (1) ◽  
pp. 62-78 ◽  
Author(s):  
Huey-Tsyh Chen ◽  
Michelle Rose Marks ◽  
Carl A. Bersani

Further research on the impact of unemployment on workers and their families requires greater refinement and more precise measurement of the concept. While previous studies have indicated the effects of unemployment on a wide range of variables, such as health and well-being, many of these studies suffer from imprecision by conceptualizing unemployment too narrowly and by using too strict a dichotomy between currently employed and currently unemployed workers. This research effort attempts to broaden and refine the concept of unemployment by defining it in terms of two job dimensions: current employment status and previous job loss. Using this conceptualization, the authors find that current unemployment after other job losses may have more devastating effects on well-being than losing one's job for the first time. Similarly, among the currently employed, those who have lost jobs in the past may experience more emotional difficulties than those who have never lost their jobs.


Author(s):  
A. Strojnik ◽  
J.W. Scholl ◽  
V. Bevc

The electron accelerator, as inserted between the electron source (injector) and the imaging column of the HVEM, is usually a strong lens and should be optimized in order to ensure high brightness over a wide range of accelerating voltages and illuminating conditions. This is especially true in the case of the STEM where the brightness directly determines the highest resolution attainable. In the past, the optical behavior of accelerators was usually determined for a particular configuration. During the development of the accelerator for the Arizona 1 MEV STEM, systematic investigation was made of the major optical properties for a variety of electrode configurations, number of stages N, accelerating voltages, 1 and 10 MEV, and a range of injection voltages ϕ0 = 1, 3, 10, 30, 100, 300 kV).


2020 ◽  
Vol 04 (04) ◽  
pp. 369-372
Author(s):  
Paul B. Romesser ◽  
Christopher H. Crane

AbstractEvasion of immune recognition is a hallmark of cancer that facilitates tumorigenesis, maintenance, and progression. Systemic immune activation can incite tumor recognition and stimulate potent antitumor responses. While the concept of antitumor immunity is not new, there is renewed interest in tumor immunology given the clinical success of immune modulators in a wide range of cancer subtypes over the past decade. One particularly interesting, yet exceedingly rare phenomenon, is the abscopal response, characterized by a potent systemic antitumor response following localized tumor irradiation presumably attributed to reactivation of antitumor immunity.


2020 ◽  
Vol 1 (2) ◽  
pp. 157-172
Author(s):  
Thomas Leitch

Building on Tzvetan Todorov's observation that the detective novel ‘contains not one but two stories: the story of the crime and the story of the investigation’, this essay argues that detective novels display a remarkably wide range of attitudes toward the several pasts they represent: the pasts of the crime, the community, the criminal, the detective, and public history. It traces a series of defining shifts in these attitudes through the evolution of five distinct subgenres of detective fiction: exploits of a Great Detective like Sherlock Holmes, Golden Age whodunits that pose as intellectual puzzles to be solved, hardboiled stories that invoke a distant past that the present both breaks with and echoes, police procedurals that unfold in an indefinitely extended present, and historical mysteries that nostalgically fetishize the past. It concludes with a brief consideration of genre readers’ own ambivalent phenomenological investment in the past, present, and future each detective story projects.


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