A free pseudospace

2000 ◽  
Vol 65 (1) ◽  
pp. 443-460 ◽  
Author(s):  
Andreas Baudisch ◽  
Anand Pillay

In this paper we construct a non-CM -trivial stable theory in which no infinite field is interpretable. In fact our theory will also be trivial and ω-stable, but of infinite Morley rank. A long term aim would be to find a non CM-trivial theory which has finite Morley rank (or is even strongly minimal) and does not interpret a field. The construction in this paper is direct, and is a “3-dimensional” version of the free pseudoplane. In a sense we are cheating: the original point of the notion of CM-triviality was to describe the geometry of a strongly minimal set, or even of a regular type. In our example, non-CM-triviality will come from the behaviour of three orthogonal regular types.A stable theory is said to be CM-trivial if whenever A ⊆ B and acl(Ac) ∩ acl(B) = acl(A) in Teq, then Cb(stp(c/A)) ⊆ Cb(stp(c/B)). ( An infinite stable field will not be CM-trivial.) The notion is due to Hrushovski [3], where he gave several equivalent definitions, as well as showing that his new strongly minimal sets constructed “ab ovo” were CM-trivial. The notion was studied further in [6] where it was shown that CM-trivial groups of finite Morley rank are nilpotent-by-finite. These results were generalized in various ways to the superstable case in [8].

1996 ◽  
Vol 86 (3) ◽  
pp. 289-296 ◽  
Author(s):  
Marc J.B. Vreysen ◽  
Issa S. Khamis ◽  
André M.V. Van der Vloedt

AbstractMonitoring of Glossina austeni Newstead populations in the forested areas of Unguja island of Zanzibar has since November 1990 routinely been carried out with the sticky panel trap because commonly used tsetse traps (Biconical, Epsilon, F3) have proved to be unsuccessful in catching G. austeni. Initial studies on the catching ability of various types of sticky panels for G. austeni indicated that the monopanel was as efficient in catching flies as the 3-dimensional version and the smaller legpanel. No significant differences in catch rate and sex ratio were observed with monopanels in various colours and colour combinations. Legpanels coloured white on one panel side and blue on the other side caught significantly more flies compared with other colour combinations, but female flies were under-sampled (32%). The type of sticky material applied on the panel influenced significantly the catch rate and female ratio. During long-term trapping with baby blue and white monopanels, females were under-sampled (38–46%) except when polyisobutyleneLMW was used as sticky material. Analysis of the age composition of the sampled G. austeni females revealed that tenerals and nulliparous were well represented (11–24%). More than 20% of the trapped females were older flies, i.e. females with four or more ovulations, but this percentage dropped to 10% when Tanglefoot was used as sticky material.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Marisa Nacke ◽  
Emma Sandilands ◽  
Konstantina Nikolatou ◽  
Álvaro Román-Fernández ◽  
Susan Mason ◽  
...  

AbstractThe signalling pathways underpinning cell growth and invasion use overlapping components, yet how mutually exclusive cellular responses occur is unclear. Here, we report development of 3-Dimensional culture analyses to separately quantify growth and invasion. We identify that alternate variants of IQSEC1, an ARF GTPase Exchange Factor, act as switches to promote invasion over growth by controlling phosphoinositide metabolism. All IQSEC1 variants activate ARF5- and ARF6-dependent PIP5-kinase to promote PI(3,4,5)P3-AKT signalling and growth. In contrast, select pro-invasive IQSEC1 variants promote PI(3,4,5)P3 production to form invasion-driving protrusions. Inhibition of IQSEC1 attenuates invasion in vitro and metastasis in vivo. Induction of pro-invasive IQSEC1 variants and elevated IQSEC1 expression occurs in a number of tumour types and is associated with higher-grade metastatic cancer, activation of PI(3,4,5)P3 signalling, and predicts long-term poor outcome across multiple cancers. IQSEC1-regulated phosphoinositide metabolism therefore is a switch to induce invasion over growth in response to the same external signal. Targeting IQSEC1 as the central regulator of this switch may represent a therapeutic vulnerability to stop metastasis.


2013 ◽  
Vol 7 ◽  
pp. CMC.S11501 ◽  
Author(s):  
Mazen T. Ghanem ◽  
Rania S. Ahmed ◽  
Ayman M. Abd El Moteleb ◽  
John K. Zarif

During ablation of re-entrant ventricular tachycardia (VT) 3-dimensional mapping systems are now used to properly delineate the scar tissue and aid ablation of scar-related VT. The aim of our study was to outline how the mode of ablation predicts success and recurrence in large scar-related VT. When comparing patients with recurrence and patients with no recurrence, univariate analysis showed that number of ablation lesions (28 ± 8 vs. 12 ± 8, P = 0.01) and more linear ablation lesions rather than focal lesions ( P = 0.03) were associated with long-term success. We demonstrated that more extensive ablation lesions and creation of linear lesions is associated with better success rate and lower recurrence rate during ablation of large scar-related ventricular tachycardia.


1999 ◽  
Vol 211 (2) ◽  
pp. 409-456 ◽  
Author(s):  
Tuna Altınel ◽  
Alexandre Borovik ◽  
Gregory Cherlin

1999 ◽  
Vol 64 (3) ◽  
pp. 1280-1284 ◽  
Author(s):  
Ehud Hrushovski ◽  
Thomas Scanlon

We note here, in answer to a question of Poizat, that the Morley and Lascar ranks need not coincide in differentially closed fields. We will approach this through the (perhaps) more fundamental issue of the variation of Morley rank in families. We will be interested here only in sets of finite Morley rank. Section 1 consists of some general lemmas relating the above issues. Section 2 points out a family of sets of finite Morley rank, whose Morley rank exhibits discontinuous upward jumps. To make the base of the family itself have finite Morley rank, we use a theorem of Buium.


1991 ◽  
Vol 56 (4) ◽  
pp. 1184-1194 ◽  
Author(s):  
Steven Buechler

AbstractLet D be a strongly minimal set in the language L, and D′ ⊃ D an elementary extension with infinite dimension over D. Add to L a unary predicate symbol D and let T′ be the theory of the structure (D′, D), where D interprets the predicate D. It is known that T′ is ω-stable. We proveTheorem A. If D is not locally modular, then T′ has Morley rank ω.We say that a strongly minimal set D is pseudoprojective if it is nontrivial and there is a k < ω such that, for all a, b ∈ D and closed X ⊂ D, a ∈ cl(Xb) ⇒ there is a Y ⊂ X with a ∈ cl(Yb) and ∣Y∣ ≤ k. Using Theorem A, we proveTheorem B. If a strongly minimal set D is pseudoprojective, then D is locally projective.The following result of Hrushovski's (proved in §4) plays a part in the proof of Theorem B.Theorem C. Suppose that D is strongly minimal, and there is some proper elementary extension D1 of D such that the theory of the pair (D1, D) is ω1-categorical. Then D is locally modular.


2009 ◽  
Vol 321 (5) ◽  
pp. 1383-1406 ◽  
Author(s):  
Jeffrey Burdges

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