Corrections: Covariances between Arbitrary Relatives with Linkage and Epistasis, in the case of Linkage Disequlibrium

Biometrics ◽  
1977 ◽  
Vol 33 (4) ◽  
pp. 766
Keyword(s):  
Linkage Disequlibrium

scholarly journals High-resolution estimates of crossover and noncrossover recombination from a captive baboon colony

2021 ◽  
Author(s):  
Jeff Wall ◽  
Jacqueline A Robinson ◽  
Laura A Cox
Keyword(s):  
High Resolution ◽  
Homologous Recombination ◽  
Geometric Distribution ◽  
Length Distribution ◽  
Model Organisms ◽  
Distribution Model ◽  
Recombination Rates ◽  
Papio Anubis ◽  
Olive Baboons ◽  
Linkage Disequlibrium

Homologous recombination has been extensively studied in humans and a handful of model organisms. Much less is known about recombination in other species, including non-human primates. Here we present a study of crossovers and non-crossover (NCO) recombination in olive baboons (Papio anubis) from two pedigrees containing a total of 20 paternal and 17 maternal meioses, and compare these results to linkage-disequlibrium (LD) based recombination estimates from 36 unrelated olive baboons. We demonstrate how crossovers, combined with LD-based recombination estimates, can be used to identify genome assembly errors. We also quantify sex-specific differences in recombination rates, including elevated male crossover and reduced female crossover rates near telomeres. Finally, we add to the increasing body of evidence suggesting that while most NCO recombination tracts in mammals are short (e.g., < 500 bp), there are a non-negligible fraction of longer (e.g., > 1 Kb) NCO tracts. We fit a mixture-of-two-geometric distributions model to the NCO tract length distribution and estimate that >99% of all NCO tracts are very short (mean 24 bp), but the remaining tracts can be quite long (mean 11 Kb). A single geometric distribution model for NCO tract lengths is incompatible with the data, suggesting that LD-based methods for estimating NCO recombination rates that make this assumption may need to be modified.

scholarly journals Linkage disequlibrium in populations of Merodon avidus A. (Diptera, Syrphidae)

2004 ◽  
pp. 45-53 ◽  
Author(s):  
Vesna Milankov ◽  
Jasmina Ludoski ◽  
Ante Vujic
Keyword(s):  
Genetic Structure ◽  
Gel Electrophoresis ◽  
Polyacrylamide Gel Electrophoresis ◽  
Polyacrylamide Gel ◽  
Gametic Disequilibrium ◽  
Linkage Disequlibrium

Analysis of the genetic structure in the populations of Merodon avidus A originated from the Dubasnica Mountain, Serbia (AADUB), Pindos Mountain Greece (AAPIN) and Morinj, Montenegro (AAMOR) was done. Based on the polyacrylamide gel electrophoresis out of 16 analyzed loci 10 izozymic loci were monomorphic: Aat, Fum, Hk-2, Hk-3, Idh-2, Mdh-1, Pgm, Sod-1, Sod-2 Sod-3. Nonrandom association between alleles of the Ao and Me in the AAMOR population has been registered. Significant association among alleles of the Ao and Mdh-2 loci in AADUB and Ao and Gpd-2 loci in AAPIN was found as well. Percent of the locus with observed significant gametic disequilibrium was from 16.7% in AAMOR to significant association of the only variable loci pair in AADUB and AAPIN.

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