Safety and Efficacy of in ovo Administration of Infectious Bursal Disease Viral Vaccines

2001 ◽  
Vol 45 (1) ◽  
pp. 144 ◽  
Author(s):  
J. J. Giambrone ◽  
T. Dormitorio ◽  
T. Brown
Keyword(s):  
Infectious Bursal Disease ◽  
In Ovo ◽  
Safety And Efficacy ◽  
Bursal Disease ◽  
Viral Vaccines

scholarly journals STUDY THE EFFECT OF MYCOPLASMA CONTAMINATION OF EGGS USED IN VIRUS TITRATION AND EFFICACY OF SOME LIVE ATTENUATED POULTRY VIRAL VACCINES

2016 ◽  
Vol 10 (1) ◽  
pp. 216 ◽  
Author(s):  
Marwa Fathy ◽  
Mounir M. El-safty ◽  
Jakeen K. El-jakee ◽  
Howaida I. Abd-alla ◽  
Hala Mahmoud
Keyword(s):  
Disease Virus ◽  
Newcastle Disease ◽  
Disease Process ◽  
Mycoplasma Gallisepticum ◽  
Infectious Bursal Disease ◽  
Enzyme Linked Immunosorbent Assay ◽  
Infectious Bronchitis ◽  
Bursal Disease ◽  
Specific Pathogen ◽  
Viral Vaccines

ABSTRACTObjective: The study of Mycoplasma gallisepticum (MG) infection is needed, not only to understand the disease process but also to understand theinterference with the evaluation of some live viral poultry vaccines. This study aims to investigate the titration and potency of some live attenuatedpoultry viral vaccines; Newcastle disease, infectious bronchitis, infectious bursal disease, and Reo in both specific pathogen-free (SPF) embryonatedchicken eggs (ECEs) and chickens.Methods: Titration of live attenuated viral poultry vaccines in ECEs was carried out by dividing the inoculated eggs into four groups; the pre-,simultaneously-, post-, and non-MG contaminated. MG effect on the potency test was carried out using seventeen groups of SPF chickens (25 chicken/group) placed into separate isolators. Each live attenuated viral poultry vaccine was inoculated into 4 groups.Results: The highest titer of these vaccines that appeared in MG pre- contaminated ECEs were 1011, 107.5, 107.9, and 10, respectively. The lowest vaccinetiters that appeared in non-MG contaminated ECEs were 108, 106, 106.8, and 1067.5, respectively. Although the potency of these previous vaccines indicated thatthe highest antibodies titer that appeared in MG pre-infected vaccinated chickens were 7.5 log, 36 enzyme-linked immunosorbent assay unit (EU), and42 EU, respectively; the lowest antibodies titer that appeared in non-MG infected vaccinated chickens were 6.5 log22, 12 EU, 17 EU, and 10 EU, respectively.Conclusion: The present study findings underline the importance of using Mycoplasma -free eggs or chicken for the production of virus vaccines.Keywords: Mycoplasma gallisepticum, Newcastle disease virus, Infectious bronchitis virus, Infectious bursal disease virus, Reo virus, Chicken, Specificpathogen-free eggs.

Novel in-ovo chimeric recombinant Newcastle disease vaccine protects against both Newcastle disease and infectious bursal disease

Vaccine ◽  
2014 ◽  
Vol 32 (13) ◽  
pp. 1514-1521 ◽  
Author(s):  
Jinying Ge ◽  
Xijun Wang ◽  
Meijie Tian ◽  
Zhiyuan Wen ◽  
Qiulin Feng ◽  
...  
Keyword(s):  
Newcastle Disease ◽  
Infectious Bursal Disease ◽  
In Ovo ◽  
Bursal Disease ◽  
Newcastle Disease Vaccine
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