Pathological Changes of Tracheal Mucosa in Chickens Infected with Lentogenic Newcastle Disease Virus

1987 ◽  
Vol 31 (3) ◽  
pp. 491 ◽  
Author(s):  
T. Kotani ◽  
Y. Odagiri ◽  
J. Nakamura ◽  
T. Horiuchi
Keyword(s):  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Newcastle Disease ◽  
Pathological Changes ◽  
Tracheal Mucosa

scholarly journals Humoral immune response against Newcastle disease virus and its pathological changes in vaccinated chickens in selected areas of Barisal district in Bangladesh

2020 ◽  
Vol 6 (2) ◽  
pp. 155-167
Author(s):  
Nasrin Akter Sumona ◽  
Khondoker Jahengir Alam ◽  
Md Yeasin Arafat ◽  
Imam Hasan
Keyword(s):  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Newcastle Disease ◽  
Broiler Chickens ◽  
Age Groups ◽  
Pathological Changes ◽  
Protective Level ◽  
Serum Samples ◽  
Antibody Titers ◽  
Layer Chickens

The objectives of this study were to evaluate humoral immunity against Newcastle disease (ND) virus in vaccinated chickens in terms of serum HI antibody titers in broiler and layer chickens and to determine pathological changes in vaccinated chickens. A total of 240 serum samples were collected from broiler (135) and layer (105) chickens from Barishal Sadar, Babugonj and Gournadi Upazilas of Barishal district in Bangladesh after two weeks of scheduled vaccination programme. The overall detection of Hemagglutination inhibition (HI) antibodies against Newcastle disease virus was 62.2% in broiler and 83.8% in layer chickens. The percentages of specific HI antibody titer in broiler chickens were 57.5, 70 and 48 in 1-2 weeks, 3-4 weeks, and 4-above weeks age groups respectively where in layer chickens were 85, 80, 90, 80 and 80 in 15-24 weeks, 25-34 weeks, 35-44 weeks, 45-54 weeks and > 55 weeks of age groups respectively. For both broiler and layer chicken’s protective antibody titers were found higher in adult than in young chickens. Out of 240 samples HI titers of 172 (71.67%) samples were found at protective level, 42 (17.5%) samples were at marginal level and 26 (10.83%) samples were below protective level. Among 26 samples of non-protective level, 21 were broiler and 5 were layer chicken. Out of 26 samples, 10 (38.46%) were found apparently infected with NDV where 8 (38.09%) were broiler and 2 (40%) were layer. The apparently infected birds were diagnosed on the basis of postmortem findings and histopathological lesions. Results of the present investigation may help to design appropriate vaccination schedule for ND in broiler and layer chickens and thus to protect chickens from ND in field condition. Asian J. Med. Biol. Res. June 2020, 6(2): 155-167

scholarly journals Supplementation of Vitamin E Protects Chickens from Newcastle Disease Virus-Mediated Exacerbation of Intestinal Oxidative Stress and Tissue Damage

2018 ◽  
Vol 47 (4) ◽  
pp. 1655-1666 ◽  
Author(s):  
Zaib Ur Rehman ◽  
Luping Che ◽  
Shanhui Ren ◽  
Ying Liao ◽  
Xusheng Qiu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Body Weight ◽  
Vitamin E ◽  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Newcastle Disease ◽  
Negative Control ◽  
Jejunal Mucosa ◽  
Pathological Changes ◽  
Histopathological Changes

Background/Aims: Newcastle disease virus (NDV) causes a highly devastating and contagious disease in poultry, which is mainly attributed to extensive tissue damages in the digestive, respiratory and nervous systems. However, nature and dynamics of NDV-induced oxidative stresses in the intestine of chickens remain elusive. Methods: In this study, we examined the magnitude of intestinal oxidative stress and histopathological changes caused by the virulent NDV infection, and explored the protective roles of vitamin E (vit. E) in ameliorating these pathological changes. For these purposes, chickens were divided into four groups namely i) non supplemented and non-challenged (negative control, CON); ii) no supplementation of vit. E but challenged with ZJ1 (positive control, NS+CHA); iii) vit. E supplementation at the dose of 50 IU/day/Kg body weight and ZJ1 challenge (VE50+CHA); and 4) vit. E supplementation at the dose of 100 IU/day/Kg body weight and ZJ1 challenge (VE100+CHA). In all groups, we analyzed concentrations of glutathione (GSH), malondialdehyde (MDA), nitric oxide (NO), total antioxidant capacity (T-AOC), and activity of glutathione S-transferase (GST), superoxide dismutase (SOD), catalase (CAT) using biochemical methods. The virus loads were determined by quantitative RT-PCR and antibody titers by hemagglutination inhibition assays. We also examined the histopathological changes in the duodenal and jejunal mucosa at 3 and 5-day post infection (dpi) with NDV. Results: A significant elevation in the NO level was observed in NDV challenged chickens compared to the CON chickens at 2 dpi. The MDA contents were significantly increased whereas GSH was significantly decreased in NDV-challenged chickens compared to control. Furthermore, activities of GST, CAT, SOD, as well as the TOAC were markedly decreased in challenged chickens in comparison with control. Virus copy numbers were higher in NDV infected NS+CHA group compared to other groups. Severe histopathological changes including inflammation, degeneration and broken villi were observed in the intestine of NDV challenged chickens. However, all these malfunctions of antioxidant system and pathological changes in the intestine were partially or completely reversed by the vit. E supplementation. Conclusions: Our results suggest that NDV infection causes oxidative stress and histopathological changes in the duodenum and jejunum of chickens, which can be partially or fully ameliorated by supplementation of vit. E. Additionally, these findings suggest that oxidative stress contributes to the intestinal damages in NDV infected chickens. These findings will help to understand the pathogenesis of NDV and further investigation of therapeutic agents for control of Newcastle disease.

scholarly journals Clinical and gross-pathological changes in Muscovy ducks and Nigerian local chickens infected with Newcastle disease virus (XIVb strain)

2021 ◽  
Vol 18 (4) ◽  
pp. 182-190
Author(s):  
S.G. Usman ◽  
S.B. Oladele ◽  
L. Saidu ◽  
M.S. Muhammed ◽  
F.S. Umar ◽  
...  
Keyword(s):  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Newcastle Disease ◽  
Pathological Changes ◽  
Muscovy Ducks ◽  
Local Chickens

No Abstract.

Characterization of Recent Isolates of Newcastle Disease virus

2016 ◽  
Vol 21 (1) ◽  
pp. 235-248
Author(s):  
Amani Saleh ◽  
Rola Ali ◽  
Mohamed Fawzy ◽  
Mokhtar Eltarabily
Keyword(s):  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Newcastle Disease

Transcription and translation of Newcastle disease virus mRNA's in vitro.

1978 ◽  
Vol 28 (1) ◽  
pp. 324-336 ◽  
Author(s):  
P L Collins ◽  
L E Hightower ◽  
L A Ball
Keyword(s):  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Newcastle Disease
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