Comb Lesions and Mortality Patterns in White Leghorn Layers Affected by Marek's Disease

1983 ◽  
Vol 27 (2) ◽  
pp. 503 ◽  
Author(s):  
H. E. Ekperigin ◽  
A. M. Fadly ◽  
L. F. Lee ◽  
X. Liu ◽  
R. H. McCapes
Keyword(s):  
Marek's Disease ◽  
Marek’S Disease ◽  
White Leghorn

Selection for Resistance to Marek's Disease and Its Expected Effects on Other Important Traits in White Leghorn Strain Crosses

1972 ◽  
Vol 16 (1) ◽  
pp. 11 ◽  
Author(s):  
C. M. von Krosigk ◽  
C. F. McClary ◽  
E. Vielitz ◽  
D. V. Zander
Keyword(s):  
Marek's Disease ◽  
Marek’S Disease ◽  
White Leghorn ◽  
Selection For

scholarly journals Genetics and vaccine efficacy: Host genetic variation affecting Marek’s disease vaccine efficacy in White Leghorn chickens

2010 ◽  
Vol 89 (10) ◽  
pp. 2083-2091 ◽  
Author(s):  
S. Chang ◽  
J.R. Dunn ◽  
M. Heidari ◽  
L.F. Lee ◽  
J. Song ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Vaccine Efficacy ◽  
Marek's Disease ◽  
Marek’S Disease ◽  
White Leghorn ◽  
Host Genetic

Mapping of susceptibility to Marek's disease within the major histocompatibility (B) complex by refined typing of White Leghorn chickens

2009 ◽  
Vol 24 (4) ◽  
pp. 283-287 ◽  
Author(s):  
B. G. Hepkema ◽  
E. J. Hensen ◽  
J. J. Blankert ◽  
A. J. Zijpp ◽  
G. A. A. Albers ◽  
...  
Keyword(s):  
Marek's Disease ◽  
Marek’S Disease ◽  
Major Histocompatibility ◽  
White Leghorn

scholarly journals Enhancement of spontaneous bursal lymphoma frequency by serotype 2 Marek's disease vaccine, SB-1, in transgenic and non-transgenic line 0 white leghorn chickens

1999 ◽  
Vol 28 (2) ◽  
pp. 147-154 ◽  
Author(s):  
D. W. Salter ◽  
W. Payne ◽  
H-J. Kung ◽  
D. Robinson ◽  
D. Ewert ◽  
...  
Keyword(s):  
Transgenic Line ◽  
Marek's Disease ◽  
Marek’S Disease ◽  
White Leghorn

Electron Microscopy of a Herpesvirus Isolated from Marek's Disease in Duck and Chicken Embryo Fibroblast Cultures

1968 ◽  
Vol 26 ◽  
pp. 222-223 ◽  
Author(s):  
Keyvan Nazerian
Keyword(s):  
Inclusion Bodies ◽  
Chicken Embryo Fibroblast ◽  
Marek's Disease ◽  
Marek’S Disease ◽  
Duck Embryo Fibroblast ◽  
Multinucleated Cells ◽  
Viral Particles ◽  
Infected Cells ◽  
And Control ◽  
Do So

A herpes-like virus has been isolated from duck embryo fibroblast (DEF) cultures inoculated with blood from Marek's disease (MD) infected birds. Cultures which contained this virus produced MD in susceptible chickens while virus negative cultures and control cultures failed to do so. This and other circumstantial evidence including similarities in properties of the virus and the MD agent implicate this virus in the etiology of MD.Histochemical studies demonstrated the presence of DNA-staining intranuclear inclusion bodies in polykarocytes in infected cultures. Distinct nucleo-plasmic aggregates were also seen in sections of similar multinucleated cells examined with the electron microscope. These aggregates are probably the same as the inclusion bodies seen with the light microscope. Naked viral particles were observed in the nucleus of infected cells within or on the edges of the nucleoplasmic aggregates. These particles measured 95-100mμ, in diameter and rarely escaped into the cytoplasm or nuclear vesicles by budding through the nuclear membrane (Fig. 1). The enveloped particles (Fig. 2) formed in this manner measured 150-170mμ in diameter and always had a densely stained nucleoid. The virus in supernatant fluids consisted of naked capsids with 162 hollow, cylindrical capsomeres (Fig. 3). Enveloped particles were not seen in such preparations.

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