Effect of Infectious Bursal Agent on the Response of Chickens to Newcastle Disease and Marek's Disease Vaccination

1976 ◽  
Vol 20 (3) ◽  
pp. 534 ◽  
Author(s):  
J. J. Giambrone ◽  
C. S. Eidson ◽  
R. K. Page ◽  
O. J. Fletcher ◽  
B. O. Barger ◽  
...  
Keyword(s):  
Newcastle Disease ◽  
Marek's Disease ◽  
Marek’S Disease

scholarly journals Mardivirus Infection and Persistence in Feathers of a Chicken Model Harboring a Local Autoimmune Response

2020 ◽  
Vol 8 (10) ◽  
pp. 1613
Author(s):  
Gisela F. Erf ◽  
Gilles Le Pape ◽  
Sylvie Rémy ◽  
Caroline Denesvre
Keyword(s):  
Inflammatory Response ◽  
Newcastle Disease ◽  
Marek's Disease ◽  
Autoimmune Response ◽  
Marek’S Disease ◽  
Autoimmune Destruction ◽  
Strong Inflammatory Response ◽  
Destruction Of Melanocytes ◽  
Chicken Model

Herpesvirus of turkey (HVT) is commonly used as a vaccine to protect chickens against Marek’s disease. Following vaccination, HVT infects feathers where it can be detected in all chicken lines examined. Unlike the parental Brown line (BL), Smyth line (SL) chickens develop vitiligo, due to autoimmune destruction of melanocytes in feathers. Previous reports showed a strong inflammatory response in Smyth chickens’ feathers at vitiligo onset, that subsided once melanocytes were destroyed, and depigmentation was complete. Here, we questioned whether the local autoimmune response in the Smyth model influences HVT infection and persistence in feathers. For this, one-day-old SL and BL chickens were vaccinated with Newcastle disease (rHVT-ND). Vitiligo was scored and HVT loads in pigmented and non-pigmented growing feathers were quantified regularly over 20 weeks. Chickens of both lines showed moderate HVT loads in feathers. At the onset of active vitiligo, the HVT load was significantly higher in SL compared to BL feathers. However, no difference in HVT loads was noticed between pigmented and non-pigmented feathers from SL chickens. Therefore, surprisingly, the inflammatory response in feathers of SL chickens did not inhibit HVT infection and persistence, but on the contrary, temporarily promoted HVT infection in feathers.

scholarly journals DETECTION OF FIVE VIRUS INFECTIONS IN THE LAYER FARM WITH RUNTING-STUNTING SYNDROME IN SUKABUMI AND TANGERANG USING POLYMERASE CHAIN REACTION TECHNIQUE

2017 ◽  
Vol 11 (2) ◽  
Author(s):  
Risza Hartawan ◽  
Ni Luh Putu Indi Dharmayanti
Keyword(s):  
Polymerase Chain Reaction ◽  
Avian Influenza ◽  
Newcastle Disease ◽  
Viral Infections ◽  
Marek's Disease ◽  
Polymerase Chain Reaction Technique ◽  
Marek’S Disease ◽  
Chain Reaction ◽  
Field Samples ◽  
Polymerase Chain

The objective of this study was to identify the five different viral infections including avian influenza, Newcastle disease, avian reovirus, avian encephalomyelitis, and Marek’s disease in the runting-stunting syndrome outbreak in several commercial layer farms in Sukabumi and Tangerang in November 2014 using polymerase chain reaction technique. As results, this study identified mix infection of three viruses in the field samples, including Newcastle disease, reovirus, and avian encephalomyelitis; however, it was negative for avian influenza and Marek’s disease viruses. Subsequently, the inoculation of several samples into embryonated chicken eggs confirmed the growth of these three viruses. As a consequence, disease control management should be conducted in the affected farms by implementing effective biosecurity and vaccination program.

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