scholarly journals INVERTEBRATE CELL VOLUME CONTROL MECHANISMS: A COORDINATED USE OF INTRACELLULAR AMINO ACIDS AND INORGANIC IONS AS OSMOTIC SOLUTE

1982 ◽  
Vol 163 (3) ◽  
pp. 405-419 ◽  
Author(s):  
SIDNEY K. PIERCE
Keyword(s):  
Amino Acids ◽  
Cell Volume ◽  
Inorganic Ions ◽  
Volume Control ◽  
Control Mechanisms ◽  
Intracellular Amino Acids ◽  
Osmotic Solute ◽  
Cell Volume Control ◽  
Invertebrate Cell

Role of cytoskeleton in isotonic cell volume control of rabbit proximal tubules

1991 ◽  
Vol 261 (1) ◽  
pp. F60-F69 ◽  
Author(s):  
M. A. Linshaw ◽  
T. J. Macalister ◽  
L. W. Welling ◽  
C. A. Bauman ◽  
G. Z. Hebert ◽  
...  
Keyword(s):  
Cell Volume ◽  
Cytochalasin B ◽  
Renal Tubule ◽  
Proximal Tubules ◽  
Volume Control ◽  
Control Mechanisms ◽  
Volume Increase ◽  
Convoluted Tubules ◽  
Cell Volume Control

Stability of mammalian cell volume depends primarily on the sodium pump. When active cation transport of rabbit renal proximal tubules is blocked by ouabain, cells swell, but their size is limited by residual volume control mechanisms. This “ouabain-resistant” volume control is not an active process, as it operates in the presence of cyanide and dinitrophenol and in the absence of exogenous energy. Nevertheless, it remains incompletely explained by known transmembrane oncotic and hydrostatic forces. We tested the hypothesis that the cytoskeleton contributes to isotonic cell volume control. Isolated, collapsed rabbit proximal convoluted tubules (PCT) were crimped at both ends with micropipettes and had their volume assessed optically. PCT in ouabain (1 mM) swelled to 1.40 above control with protein, 1.62 without protein, and 1.89 with the cytoskeleton inhibitors vincristine (5 microM) and cytochalasin B (50 microM) and without protein. Tubulozole-C and cytochalasin D gave similar results. A hydrostatic pressure of 50 cmH2O increased tubule volume to 1.93 before the tubule basement membrane (TBM) prevented further volume increase. We conclude that volume of renal tubule cells in ouabain is limited partly by external protein, but primarily by the cytoskeleton. The TBM prevents massive swelling and tubule disaggregation.

scholarly journals Mathematical Modeling of Cell Volume Control

2020 ◽  
Vol 118 (3) ◽  
pp. 461a
Author(s):  
Maria Jesus Munoz Lopez ◽  
Yoichiro Mori
Keyword(s):  
Mathematical Modeling ◽  
Cell Volume ◽  
Volume Control ◽  
Cell Volume Control

scholarly journals Spatial Organization of Calcium Signaling Involved in Cell Volume Control in the Fucus Rhizoid.

1996 ◽  
pp. 2015-2031 ◽  
Author(s):  
A. R. Taylor ◽  
NFH. Manison ◽  
C. Fernandez ◽  
J. Wood ◽  
C. Brownlee
Keyword(s):  
Calcium Signaling ◽  
Cell Volume ◽  
Spatial Organization ◽  
Volume Control ◽  
Cell Volume Control

The Contractile Vacuole Complex and Cell Volume Control in Protozoa

2008 ◽  
pp. 69-105
Author(s):  
Richard D. Allen ◽  
Takashi Tominaga ◽  
Yutaka Naitoh
Keyword(s):  
Cell Volume ◽  
Contractile Vacuole ◽  
Volume Control ◽  
Cell Volume Control
Sign in / Sign up

Export Citation Format

Share Document