Mathematical methods of chronic diseases study in 1970

1971 ◽  
Vol 3 (2) ◽  
pp. 194-196
Author(s):  
L. D. Meshalkin

This report is based mainly on the research conducted in 1969–70 in the Division of Research in Epidemiology and Communications Science of the World Health Organization, and gives a short résumé of methods elaborated for concise descriptions of what has been observed for prognosis of subsequent development of disease, and for the planning of new studies.

1971 ◽  
Vol 3 (02) ◽  
pp. 194-196
Author(s):  
L. D. Meshalkin

This report is based mainly on the research conducted in 1969–70 in the Division of Research in Epidemiology and Communications Science of the World Health Organization, and gives a short résumé of methods elaborated for concise descriptions of what has been observed for prognosis of subsequent development of disease, and for the planning of new studies.


2019 ◽  
Author(s):  
Balgees A. Ajlan ◽  
Maram M. Alafif ◽  
Maha M. Alawi ◽  
Naeema A. Akbar ◽  
Eman K. Aldigs ◽  
...  

AbstractThe objective of this observational study was to assess the validity of the new dengue classification proposed by the World Health Organization (WHO) in 2009 and to develop pragmatic guidelines for case triage and management. This retrospective study involved 357 laboratory-confirmed cases of dengue infection diagnosed at King Abdulaziz University Hospital, Jeddah, Saudi Arabia over a 4-year period from 2014 to 2017. The sensitivity of the new classification for identifying severe cases was limited (65.0%) but higher than the old one (30 0%). It had a higher sensitivity for identifying patients who needed advanced healthcare compared to the old one (72.0% versus 32.0%, respectively). We propose adding decompensation of chronic diseases and thrombocytopenia-related bleeding to the category of severe dengue in the new classification. This modification improves sensitivity from 72.0% to 97.5% for identifying patients who need advanced healthcare without altering specificity (96.7%). It also improves sensitivity in predicting severe outcomes from 32% to 88.0%. In conclusion, the new classification had a low sensitivity for identifying patients needing advanced care and for predicting morbidity and mortality. We propose to include decompensation of chronic diseases and thrombocytopenia-related bleeding to the category of severe dengue in the new classification to improve the sensitivity of predicting cases requiring advanced care.Author summaryDengue fever, the most prevalent arthropod-borne viral disease in human, has been conventionally classified into four main categories: non-classical, classical, dengue hemorrhagic fever, and dengue shock syndrome. Several studies reported lack of correlation between the categories of the conventional classification and the disease severity. As a consequence, the World Health organization proposed in 2008 a new classification that divides dengue into two categories: non-severe and severe dengue; the non-severe dengue is further divided into two categories: dengue with warning signs and dengue without warning signs. In this retrospective study we reviewed 357 cases of dengue diagnosed in our institution over a 4-year period to assess the validity of the new dengue classification in order to develop pragmatic guidelines for case triage and management in the Emergency Departments. We found that the sensitivity of the new classification for identifying severe cases was limited even though it had a higher sensitivity for identifying patients who needed advanced healthcare compared to the old one. We propose adding decompensation of chronic diseases and low platelets-related bleeding to the category of severe dengue in the new classification. This modification dramatically improves the sensitivity for identifying patients who need advanced healthcare and the sensitivity to predict severe outcomes.


2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Xiaoyu Wu ◽  
Yami Zhang

Tumor is defined as a kind of chronic diseases by the World Health Organization. The integrative traditional Chinese and western medicine works well on the treatment of tumors, even in advanced patients or patients with recurring and metastatic tumor. However, the pathogenic mechanism of tumors is still unclear. Therefore, based on the 19th pathogenesis in Yellow Emperor's Internal Class that "Diseases producing the liquid that is clear and chill all result from coldness", the paper explores the etiology pathogenesis of malignant tumors, and the correlation between which and tumor recurrence and metastasis, and also discusses the rules for  the treatment of tumors at various stages with great method of warming yang for dispelling cold.


2010 ◽  
Vol 8 (1) ◽  
pp. 51 ◽  
Author(s):  
Olatz Garin ◽  
Jose Ayuso-Mateos ◽  
Josué Almansa ◽  
Marta Nieto ◽  
Somnath Chatterji ◽  
...  

2017 ◽  
Vol 79 (07) ◽  
pp. 526-527

Coenen M et al. [Recommendation for the collection and analysis of data on participation and disability from the perspective of the World Health Organization]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2016; 59: 1060–1067 Um eine gleichberechtigte Teilhabe an der Gesellschaft von Menschen mit Behinderung zu ermöglichen, werden zunächst Daten zu vorhandenen Einschränkungen gebraucht. Erst wenn diese detailliert erhoben wurden, können Konzepte zur Beseitigung von Problemen entwickelt werden. Ein standardisiertes Erhebungsinstrument für alle Aspekte der Funktionsfähigkeit fehlte jedoch bisher.


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