A Partition of Variance in Dental Traits of the House Mouse

1965 ◽  
Vol 46 (3) ◽  
pp. 384-388 ◽  
Author(s):  
R. S. Bader
Science ◽  
1966 ◽  
Vol 152 (3727) ◽  
pp. 1398-1400 ◽  
Author(s):  
P. Tenczar ◽  
R. S. Bader

1930 ◽  
Vol 64 (691) ◽  
pp. 188-190 ◽  
Author(s):  
Clyde E. Keeler
Keyword(s):  

1976 ◽  
Vol 49 (2) ◽  
pp. 191-199 ◽  
Author(s):  
G. Robert Lynch ◽  
Carol Becker Lynch ◽  
Marjory Dube ◽  
Cynthia Allen

Genetics ◽  
1997 ◽  
Vol 147 (3) ◽  
pp. 1303-1316
Author(s):  
Michael W Nachman

Introns of four X-linked genes (Hprt, Plp, Glra2, and Amg) were sequenced to provide an estimate of nucleotide diversity at nuclear genes within the house mouse and to test the neutral prediction that the ratio of intraspecific polymorphism to interspecific divergence is the same for different loci. Hprt and Plp lie in a region of the X chromosome that experiences relatively low recombination rates, while Glra2 and Amg lie near the telomere of the X chromosome, a region that experiences higher recombination rates. A total of 6022 bases were sequenced in each of 10 Mus domesticus and one M. caroli. Average nucleotide diversity (π) for introns within M. domesticus was quite low (π = 0.078%). However, there was substantial variation in the level of heterozygosity among loci. The two telomeric loci, Glra2 and Amg, had higher ratios of polymorphism to divergence than the two loci experiencing lower recombination rates. These results are consistent with the hypothesis that heterozygosity is reduced in regions with lower rates of recombination, although sampling of additional genes is needed to establish whether there is a general correlation between heterozygosity and recombination rate as in Drosophila melanogaster.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Petra G. Šimková ◽  
Gerhard W. Weber ◽  
Fernando V. Ramirez Rozzi ◽  
Lotfi Slimani ◽  
Jérémy Sadoine ◽  
...  

AbstractThe Baka Pygmies are known for their short stature resulting from a reduced growth rate during infancy. They are peculiar also for their teeth erupt earlier than in any other African population, and their posterior dentition is larger than in non-Pygmy populations. However, the Baka’s dental morphology, like several other aspects of their biology, is still understudied. Here, we explore the variation of the Baka’s deciduous upper and lower second molars (dm2s) in comparison to a geographically heterogeneous human sample by means of 3D geometric morphometrics and analysis of dental traits. Our results show that the different populations largely overlap based on the shape of their dm2s, especially the lower ones. Their distal region and the height of the dentinal crown differ the most, with the Baka showing the most extreme range of variation. Upper and lower dm2s covary to a great extent (RV = 0.82). The Baka’s and South Americans’ dm2s were confirmed among the largest in our sample. Despite the Baka’s unique growth pattern, long-lasting isolation, and extreme dental variation, it is not possible to distinguish them from other populations based on their dm2s’ morphology only.


eLife ◽  
2015 ◽  
Vol 4 ◽  
Author(s):  
Megan Phifer-Rixey ◽  
Michael W Nachman

The house mouse, Mus musculus, was established in the early 1900s as one of the first genetic model organisms owing to its short generation time, comparatively large litters, ease of husbandry, and visible phenotypic variants. For these reasons and because they are mammals, house mice are well suited to serve as models for human phenotypes and disease. House mice in the wild consist of at least three distinct subspecies and harbor extensive genetic and phenotypic variation both within and between these subspecies. Wild mice have been used to study a wide range of biological processes, including immunity, cancer, male sterility, adaptive evolution, and non-Mendelian inheritance. Despite the extensive variation that exists among wild mice, classical laboratory strains are derived from a limited set of founders and thus contain only a small subset of this variation. Continued efforts to study wild house mice and to create new inbred strains from wild populations have the potential to strengthen house mice as a model system.


Heredity ◽  
1947 ◽  
Vol 1 (3) ◽  
pp. 367-372 ◽  
Author(s):  
T C Carter
Keyword(s):  

2011 ◽  
Vol 65 (12) ◽  
pp. 2209-2217 ◽  
Author(s):  
Adam Dušek ◽  
Luděk Bartoš ◽  
František Sedláček

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