The Blood Sugar Concentration in Active and Hibernating Ground Squirrels

1943 ◽  
Vol 24 (4) ◽  
pp. 467 ◽  
Author(s):  
Rufus A. Lyman
Complexity ◽  
2019 ◽  
Vol 2019 ◽  
pp. 1-11 ◽  
Author(s):  
Hai-Cheng Wei ◽  
Ming-Xia Xiao ◽  
Na Ta ◽  
Hsien-Tsai Wu ◽  
Cheuk-Kwan Sun

This study investigated the validity of a novel parameter, percussion entropy index (PEI), for assessing baroreflex sensitivity. PEI was acquired through comparing the similarity in tendency of change between the amplitudes of successive digital volume pulse (DVP) signals and changes in R-R intervals (RRI) of successive cardiac cycles. Totally 108 upper middle-aged volunteers were divided into three groups: healthy subjects (Group 1, age 41–80, n=41), those with well-controlled type 2 diabetes mellitus (T2DM) (Group 2, age 41–82, n=36, glycated hemoglobin (HbA1c)<6.5%), and patients with poorly controlled T2DM (Group 3, age 44–77, n=31, HbA1c≧6.5%). Percussion entropy index (PEI) was computed from DVP signals acquired through photoplethysmography (PPG) and RRI from electrocardiogram in 1000 successive cardiac cycles for each subject. Autonomic function was also assessed by Poincaré index (SD1/SD2 ratio, SSR), low- to high-frequency power ratio (LFP/HFP, LHR), and small-scale multiscale entropy index (MEISS) for comparison. Demographic, anthropometric, hemodynamic, and serum biochemical parameters of all testing subjects were obtained for investigating the significance of associations with the three parameters. The results showed that MEISS and PEI successfully discriminated among the three groups (p<0.017). However, only PEI showed significant associations with indicators of both acute (i.e., fasting blood sugar concentration, p<0.017) and chronic (i.e., HbA1c level, p<0.001) blood sugar control. Multivariate analysis also showed significant associations of PEI with fasting blood sugar and HbA1c levels in all subjects. The interpreting effect of the two independent variables, HbA1c level and fasting blood sugar concentration, on PEI was 71.4% and 12.3%, respectively. In conclusion, the results demonstrated that additional information on diabetic autonomic dysfunction can be obtained through comparing two simultaneously acquired physiological time series. The significant associations of percussion entropy index with indicators of blood sugar control also highlight its possible role in early screening of the disease.


PEDIATRICS ◽  
1965 ◽  
Vol 35 (1) ◽  
pp. 120-123
Author(s):  
S. DOUGLAS FRASIER ◽  
FRED G. SMITH ◽  
ANDREA NASH

The response of idiopathic spontaneous hypoglycemia of infancy and childhood to therapy is variable. There is no single therapeutic agent which will uniformly maintain blood sugar concentration in the normal range in these patients. It has been suggested that a long-acting glucagon preparation may be of value when idiopathic spontaneous hypoglycemia is refractory to control by diet, corticosteroids, ACTH, ephedrine, or various combinations of these agents. It is the purpose of this paper to report our experiences with glucagon in maintaining the blood sugar concentration of a patient with idiopathic spontaneous hypoglycemia. Case Report History and Physical Examination: A 6-month-old Mexican-American boy was evaluated for convulsions which had begun at 2½ months of age.


Nature ◽  
1923 ◽  
Vol 111 (2798) ◽  
pp. 810-811 ◽  
Author(s):  
L. B. WINTER ◽  
W. SMITH

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