The Social Behavior of the Bees: A Comparative Study Charles D. Michener

BioScience ◽  
1975 ◽  
Vol 25 (7) ◽  
pp. 458-458
Author(s):  
Martin Lindauer
1976 ◽  
Vol 23 (2) ◽  
pp. 199-200 ◽  
Author(s):  
M. Lindauer

2019 ◽  
Vol 60 (2) ◽  
pp. 303-305
Author(s):  
Valdir Leite da Silva ◽  
José Cândido ◽  
José Nelson Campanha ◽  
Doraci R. de Oliveira ◽  
Carla Gheler-Costa ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Renad Jabarin ◽  
Nina Levy ◽  
Yasmin Abergel ◽  
Joshua H. Berman ◽  
Amir Zag ◽  
...  

AbstractIn this study we tested the hypothesis that pharmacological modulation of glutamatergic neurotransmission could rescue behavioral deficits exhibited by mice carrying a specific mutation in the Iqsec2 gene. The IQSEC2 protein plays a key role in glutamatergic synapses and mutations in the IQSEC2 gene are a frequent cause of neurodevelopmental disorders. We have recently reported on the molecular pathophysiology of one such mutation A350V and demonstrated that this mutation downregulates AMPA type glutamatergic receptors (AMPAR) in A350V mice. Here we sought to identify behavioral deficits in A350V mice and hypothesized that we could rescue these deficits by PF-4778574, a positive AMPAR modulator. Using a battery of social behavioral tasks, we found that A350V Iqsec2 mice exhibit specific deficits in sex preference and emotional state preference behaviors as well as in vocalizations when encountering a female mouse. The social discrimination deficits, but not the impaired vocalization, were rescued with a single dose of PF-4778574. We conclude that social behavior deficits associated with the A350V Iqsec2 mutation may be rescued by enhancing AMPAR mediated synaptic transmission.


1975 ◽  
Vol 35 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Sylvia L. Thrupp

For anyone on the green side of fifty who didn't start historical browsing in the playpen it may be quite hard to see the present appeal of statistical theory and method in perspective. To one lucky enough to have been a student abroad in the 1920's, it is merely one of the consequences of a fundamental shift, which was firming in that decade, in conceptions of the economic historian's job. Essentially the shift consisted in making the economy and the social institutions in which it is embedded analytically distinct. Voices from the Polanyite school still claim that this step was as wrong as Adam's eating of the apple. Milder critics complain only that some of us let economic analysis run away with the ball to the neglect of social analysis and of the interplay between the two. For workers on the recent past this is defensible, because the heavy fall-out of purely economic data clamors to be dealt with in its own terms. The preindustrialist, who has to dig harder for data, and seldom turns up such pure economic ore, is more inclined to think in terms of interplay.


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