scholarly journals Adjuvant Breast Disease: An Evaluation of 100 Symptomatic Women with Breast Implants or Silicone Fluid Injections.

1994 ◽  
Vol 43 (2) ◽  
pp. 79-87 ◽  
Author(s):  
Britta Ostermeyer Shoaib ◽  
Bernard M Patten ◽  
Dick S Calkins
Radiographics ◽  
1993 ◽  
Vol 13 (1) ◽  
pp. 95-118 ◽  
Author(s):  
B G Steinbach ◽  
N S Hardt ◽  
P L Abbitt ◽  
L Lanier ◽  
H H Caffee

1993 ◽  
Vol 86 (Supplement) ◽  
pp. 53
Author(s):  
Britta Ostermeyer Shoaib ◽  
Bernard M. Patten

Author(s):  
R.P. Apkarian ◽  
J.S. Sanfilippo

The synthetic androgen danazol, is an isoxazol derivative of ethisterone. It is utilized in the treatment of endometriosis, fibrocystic breast disease, and has a potential use as a contraceptive. A study was designed to evaluate the ultrastructural changes associated with danazol therapy in a rat model. The preliminary investigation of the distal segment of the rat uterine horn was undertaken as part of a larger study intended to elucidate the effects of danazol on the female reproductive tract.Cross-sections (2-3 mm in length) of the distal segment of the uterine horn from sixteen Sprague-Dawley rats were prepared for SEM. Ten rats in estrus served as controls and six danazol treated rats were noted to have alterations of the estrus cycle i.e. a lag in cycle phase or noncycling patterns. Specimens were fixed in 3% glutaraldehyde in 0.05M phosphate buffer containing CaCl2 at pH 7.0-7.4 and chilled to 4°C. After a brief wash in distilled water, specimens were passed through a graded series of ethanol, critical point dryed in CO2 from absolute ethanol, and coated with 6nm Au. Observations were made with an IS1-40 SEM operated at 15kV.


Author(s):  
K. Chien ◽  
R.L. Van de Velde ◽  
R.C. Heusser

Sectioning quality of epoxy resins can be improved by the addition of a 1% silicone 200 fluid (Dow Corning), however this produces a softer block. To compensate, a harder plastic has been used for embedding various tissues encountered in our pathology laboratory. Exact amounts of the plastic mixture can be directly made up for embedding as shown: The chart reveals a Poly/Bed 812 (WPE 145) to anhydride ratio of 1:0.7 and a NMA to DDSA ratio of 7:3. 1% silicone fluid is added to above mixtures.Due to impurities within the DDSA and NMA, the polymerized epoxy blocks vary in darkness and appear to affect sectioning quality. After discussing this problem with Polysciences Inc., they have agreed to purify their anhydrides in an effort to standardize the consistency of the plastic.


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