scholarly journals Phytosphingosine-containing Neutral Glycosphingolipids and Sulfatides in the Human Female Genital Tract: Their Association in the Cervical Epithelium and the Uterine Endometrium and Their Dissociation in the Mucosa of Fallopian Tube with the Menstrual Cycle.

1992 ◽  
Vol 41 (3) ◽  
pp. 161-167 ◽  
Author(s):  
Kiyoshi Takamatsu
1995 ◽  
Vol 269 (1) ◽  
pp. E108-E117 ◽  
Author(s):  
B. R. Steenstrup ◽  
P. Alm ◽  
J. Hannibal ◽  
J. C. Jorgensen ◽  
C. Palle ◽  
...  

The distribution, localization, and smooth muscle effects of pituitary adenylate cyclase-activating polypeptide (PACAP) were studied in the human female genital tract. The concentrations of PACAP-38 and PACAP-27 were measured by radioimmunoassays, and both peptides were found throughout the genital tract. The highest concentrations of PACAP-38 were detected in the ovary, the upper part of vagina, and the perineum. The concentrations of PACAP-27 were generally low, in some regions below the detection limit and in other regions 1 to 5% of the PACAP-38 concentrations. Immunocytochemistry revealed that PACAP was located in delicate varicose nerve fibers that were most abundant in the internal cervical os, where they mainly seemed to innervate blood vessels and smooth muscle cells. PACAP-38 and PACAP-27 (10(-10)-10(-6) M) caused a concentration-dependent relaxation of the spontaneous activity of the nonvascular smooth muscle strips from fallopian tube and myometrium in vitro. Likewise, both peptides (10(-10)-10(-6) M) caused relaxation of nonrepinephrine (10(-6) M)-precontracted intramyometrial arteries. No effect of the PACAP sequences, PACAP-(6-27), PACAP-(16-38), and PACAP-(18-27), on fallopian tube was observed. The findings suggest a smooth muscle regulatory role of PACAP in the human female reproductive tract.


1971 ◽  
Vol 68 (2) ◽  
pp. 413-416 ◽  
Author(s):  
C. Hirschhäuser ◽  
M. Kionke ◽  
E. Daume ◽  
R. Buchholz

ABSTRACT The human genital tract contains inhibitors of trypsin in cervical mucus, uterine endometrium, uterine mucus, Fallopian tubes and their secretion products.


1989 ◽  
Vol 257 (2) ◽  
pp. E220-E227 ◽  
Author(s):  
J. C. Jorgensen ◽  
S. P. Sheikh ◽  
A. Forman ◽  
M. Norgard ◽  
T. W. Schwartz ◽  
...  

The distribution, localization, and smooth muscle effects of neuropeptide Y (NPY) were studied in the human female genital tract. High concentrations of NPY immunoreactivity were demonstrated in the uterine artery, the ovary, the fallopian tube, cervix, and the vagina. The NPY immunoreactivity was confined to nerve fibers. The highest density of nerve fibers was observed in relation to blood vessels, although some NPY-immunoreactive nerves were also seen close to nonvascular smooth muscle. The NPY-immunoreactive material throughout the genital tract was identical to synthetic amidated human NPY with regard to size, hydrophobicity, and charge as evaluated by gel filtration, high-performance liquid chromatography, and isoelectric focusing. NPY (10(-10) to 10(-6) M) exerted a direct vasoconstrictory effect on small arteries dissected from the cervix and an additive effect of NPY and norepinephrine responses was observed. Exogenous NPY did not have a direct effect on nonvascular smooth muscle specimens from the fallopian tube or the myometrium. The close relation between NPY-immunoreactive nerves and blood vessels, the presence of NPY-immunoreactive material identical to amidated synthetic human NPY, and the vasoconstrictory effects of NPY indicate that NPY is involved in the regulation of the blood flow in the human female genital tract.


Immunology ◽  
2006 ◽  
Vol 117 (2) ◽  
pp. 220-228 ◽  
Author(s):  
Rafael Jimenez-Flores ◽  
Rene Mendez-Cruz ◽  
Jorge Ojeda-Ortiz ◽  
Rebeca Munoz-Molina ◽  
Oscar Balderas-Carrillo ◽  
...  

2017 ◽  
Vol 15 ◽  
pp. 18-20 ◽  
Author(s):  
K. Diop ◽  
O. Mediannikov ◽  
D. Raoult ◽  
F. Bretelle ◽  
F. Fenollar

1909 ◽  
Vol 29 ◽  
pp. 607-618
Author(s):  
D. Berry Hart

(Abstract)It has long been known that the male and the female human genital tract contain not only organs characteristic of their sex proper, but also certain parts of the opposite sex in a less developed but yet perfectly definite form. Thus the female genital tract is made up of, not only its characteristic organs, the ovaries, tubes, uterus, etc., but also the epoophoron (parovarium) and its duct, the equivalent of the epididymis and ductus epididymis of the testis. In the same way, the human male has his characteristic sexual organs and also the appendix testis and prostatic utricle, the representatives of the fimbriated end of the Fallopian tube and of the lower end of the vaginal tract (hymen mainly, but varying).


2016 ◽  
Vol 2 ◽  
pp. 19-20 ◽  
Author(s):  
Khoudia Diop ◽  
Florence Bretelle ◽  
Pierre-Edouard Fournier ◽  
Didier Raoult ◽  
Florence Fenollar

PLoS ONE ◽  
2015 ◽  
Vol 10 (6) ◽  
pp. e0131405 ◽  
Author(s):  
Karolin Hijazi ◽  
Anna M. Cuppone ◽  
Kieron Smith ◽  
Maria A. Stincarelli ◽  
Julia Ekeruche-Makinde ◽  
...  

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