Introduction. During the period from 1993 - 2013, 175 women with invasive
cervical cancer underwent radical hysterectomy sec. Wertheim-Meigs at the
Department of Gynecology and Obstetrics, Clinical Center of Vojvodina in
Novi Sad. Indications for radical hysterectomy comprise histopathologically
confirmed invasive cervical cancer in stages I B 1 - II B according to the
International Federation of Gynecology and Obstetrics. Material and Methods.
Stage of the disease or extent of the disease spread to the adjacent
structures was assessed in accordance with the International Federation of
Gynecology and Obstetrics staging system from 2009. Exclusion criteria were
all other stages of this disease: I A and stages higher than II B, as well
as the absence of definite histological confirmation of the cervical cancer
(primary endometrial or vaginal cancer which infiltrates the uterine
cervix). Prior the operation, the following had to be done: the imaging of
pelvis and abdomen, chest X-ray in two directions, electrocardiography,
internist and anesthesiological examination. Results. The patients? age
ranged from 24-79 years (x : 46 years), and the operation duration was
120-300 minutes (x : 210 min.). Stage I B 1 was found in 64.6% of operated
patients, 14.8% of the patients were in stage I B 2, 9.1% were in stage II A
and 11.4 % were in stage II B. Blood loss during the operation ranged from
50-800 ml (on average 300 ml), and the number of removed lymph nodes per
operation was 14-75 (x : 32). Intraoperative and postoperative complications
developed in 6.8% of and 17.7% of patients, respectively. Recurrence was
reported in 22 (12.5%) patients, most often in paraaortic lymph nodes (3.4%)
and parametria (2.8%), while the overall 5-year survival rate was 87% until
2008. Concluision. Wertheim-Meigs radical hysterectomy is a basic surgical
technique for the treatment of initial stages of invasive cervical cancer.