scholarly journals Coexistence of Hashimoto's thyroiditis and papillary thyroidal carcinoma with papillary carcinoma of thyreoglossal duct

2007 ◽  
Vol 64 (10) ◽  
pp. 714-718
Author(s):  
Milica Cizmic ◽  
Mile Ignjatovic ◽  
Snezana Cerovic ◽  
Boris Ajdinovic
Keyword(s):  
Thyroid Gland ◽  
Papillary Carcinoma ◽  
Hashimoto’S Thyroiditis ◽  
Clinical Investigation ◽  
The Body ◽  
Whole Body ◽  
Hashimoto's Thyroiditis ◽  
Thyroglossal Duct ◽  
Right Lobe ◽  
The Right

Background. Simultaneous presence of Hashimoto's thyroiditis and papillary thyroidal carcinoma in thyroidal gland with papillary carcinoma association in thyroglossal duct is quite rare. The questions like where the original site of primary process, is where metastasis is, what the cause of coexisting of these diseasesis present a diagnostic dilemma. Case report. We presented a case of a 53-year old female patient, with the diagnosis of Hashimoto's thyroiditis and symptoms of subclinical hypothyreosis and nodal changes in the right lobe of thyroidal gland, according to clinical investigation. Morphological examination of thyroidal gland, ultrasound examination and scintigraphy with technetium (Tc) confirmed the existence of nonhomogenic tissue with parenchyma nodular changes in the right lobe of thyroidal gland that weakly bonded Tc. Fine needle biopsy in nodal changes, with cytological analyses showed no evidence of atypical thyreocites. Hashimoto's thyroiditis was confirmed on the basis of the increased values of anti-microsomal antibodies, the high levels of thyreogobulin 117 ng/ml and TSH 6.29 ?IU/ml. The operation near by the nodular change in the right lobe of thyroidal gland revealed pyramidal lobe spread in the thyroglossal duct. Total thyroidectomia was done with the elimination of thyroglossal duct. Final patohystological findings showed papillary carcinoma in the nodal changes pT2, N0 and in the thyroglossal duct with the presence of Hashimoto's thyroiditis in the residual parenchyme of the thyroid gland. After the surgery the whole body scintigraphy with iodine 131 (131I) did not reveal accumulation of 131I in the body, while the fixation in the neck was 1%. After that, the patient was treated with thyroxin with suppressionsubstitution doses. Conclusion. Abnormality in embrional development of thyroidal tissue might be the source of thyroidal carcinoma or the way of spreading of metastasis of primary thyroidal carcinoma from thyroid gland. The cause of this process is most probably a hereditary mutation in RET oncogenes.

scholarly journals Life and Heritage of Hakaru Hashimoto

2021 ◽  
Vol 17 (2) ◽  
pp. 20-23
Author(s):  
E. A. Lygina ◽  
V. V. Latyi
Keyword(s):  
Thyroid Gland ◽  
Hashimoto’S Thyroiditis ◽  
The Body ◽  
Hashimoto's Thyroiditis ◽  
New Disease ◽  
Main Work ◽  
Long Time ◽  
Autoimmune Reactivity ◽  
First Time

In May 2021, the 140th anniversary of his birth is celebrated by Japanese doctor Hakaru Hashimoto. Did not receive recognition during his lifetime, this amazing scientist discovered a new disease of the thyroid gland, which later became the eponym. For a long time, his name was forgotten, but the main work of his life was decades ahead of the development of science. Without it, the study of autoimmune pathologies, the incidence of which currently continues to increase, would be impossible. It was on patients with Hashimoto’s thyroiditis that a study was conducted for the first time, demonstrating not only the uniqueness of the pathogenesis of thyroiditis, but also the existence of autoimmune reactivity of the body as a whole.

scholarly journals Determination of Relationship between Thyroid Gland Volume and Anthropometric Indices

2019 ◽  
pp. 1-12
Author(s):  
A. J. Salaam ◽  
S. M. Danjem ◽  
A. A. Salaam ◽  
H. A. Angba ◽  
P. O. Ibinaiye
Keyword(s):  
Thyroid Gland ◽  
Thyroid Volume ◽  
Left Lobe ◽  
The Body ◽  
Gland Volume ◽  
Thyroid Gland Volume ◽  
Right Lobe ◽  
Males And Females ◽  
The Mean ◽  
The Right

Objective: To sonographically determine the thyroid gland volume in normal adults in Jos University Teaching Hospital, as well as how it relates to anthropometric factors. Background: The thyroid gland is one of the largest endocrine glands in the body weighing about 10-25g.  It regulates the rate of metabolism and controls the growth and rate of function of many other systems in the body. These it does, by producing thyroid hormones, principally thyroxine (T4) and triiodothyronine (T3). The accurate estimation of the size of the thyroid is very important for the evaluation and management of thyroid disorders. Thus, knowing the normal size in a geographic location would form a baseline for detecting abnormalities. Ultrasonography is a cheap, readily available, easy to perform and non-invasive method to image the thyroid gland, hence its use in this resource-limited setting. Methods: This is a cross-sectional study of sonographic measurement of thyroid gland volume on 400 normal (healthy) adults in Jos, Plateau State, Northern part of Nigeria. All examinations were performed using LOGIC 5, a real-time ultrasound machine using a 10MHZ linear transducer and ultrasound transmission gel to act as a coupling gel. Measurements of each lobe and isthmus were obtained in longitudinal (length), transverse (width) and depth(breath) in centimetres (cm). Blood samples were taken for thyroid function tests. The weight and heights were obtained. The data obtained were statistically analyzed using SPSS software version 17. The results were presented in forms of tables, graphs and chart. Results: The mean thyroid volume for males   6.03 cm3±2.22 was higher than that of females 5.62 cm3±2.14. The mean right lobe volume (RLV) was 3.09 cm3±1.47 and that of males and females were 3.16 cm3 ±1.34 and 3.04 cm3 ±1.55 respectively. The mean left lobe volume (LLV) was 2.69 cm3 ± 1.37 and that of males and females were 2.89 cm3±1.32 and 2.57 cm3±1.39 respectively. The right lobe volume was significantly greater than the left lobe(p=0.000). The total mean isthmus volume was 0.27 cm3±0.31. The mean isthmus volume in males 0.3±0.28 is significantly higher than that of females 0.24±0.23 (p=0.025). The BMI increases in females with increasing age. BMI and BSA are higher in males. Conclusion: The volume obtained in this study was slightly lower than those reported by previous studies in Nigerian adults. The right lobe volume was higher than that of the left and the volume was higher in males compared to females. Anthropometric parameters were noted to affect the thyroid volume.

scholarly journals Histological Study on the Thyroid Tissue Adjoining the Noninvasive Thyroid Follicular Neoplasm With Papillary-Like Nuclear Features, Seeking a Possible Association With Hashimoto’s Thyroiditis

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A861-A862
Author(s):  
Paola N Pereira
Keyword(s):  
Hashimoto’S Thyroiditis ◽  
Histological Study ◽  
Psychological Impact ◽  
Thyroid Tissue ◽  
Hashimoto's Thyroiditis ◽  
Follicular Neoplasm ◽  
Research Committee ◽  
Non Invasive ◽  
Right Lobe ◽  
The Right

Abstract Papillary thyroid carcinoma (PTC) is the most frequent type of thyroid cancer (TC), and advances in ultrasound methods resulted in better and higher detection of this tumor. Thus, the increase in the incidence of PTC is due to the detection of microcarcinomas by ultrasound, as well as partially, due to the increased diagnosis of the encapsulated and/or well-defined non-invasive follicular variant of thyroid papillary carcinoma (NIEFVPTC). Recently, there was a change in the histological classification of NIEFVPTC, currently known as non-invasive follicular thyroid neoplasm with papillary-like features (NIFTP), thus the clinical evidence leads to an excellent prognosis once its a indolent neoplasia, dismissing additional treatments as lymphadenectomy and radioiodotherapy, therefore reducing psychological impact. This study was approved by the ethics and research committee and addressed the analysis and review of histological slides of thyroid neoplasia that currently meet the criteria for NIFTP. Furthermore, the study sought to evaluate the concomitant existence of NIFTP with histological findings consistent with Hashimoto’s Thyroiditis (HT). Underlying studies evoke a possible increase in the imperil of developing PTC when associated with HT. It should be noted that this morphological correlation is poorly described in the literature. Accordingly, a retrospective study was carried out by histological review of 232 cases diagnosed as PTC from total thyroidectomies with cervical lymphadenectomy from 1993 to 2014, previously diagnosed as NIEFVPTC. The histological slides of these cases came from the Surgical Pathology files of the Pathology Department of UNICAMP, Brazil. After histological review, 14 cases reclassified as NIFTP were selected, all referring to female patients, of which 6 presented histological criteria of NIFTP associated with HT. Additionally, a histological and laboratory correlation of the 14 selected cases was performed through the dosages of relevant serum titers of antithyroid antibodies (anti-TPO and TgAb). Out of the 6 patients detected with association of NIFTP and TH, 5 had significant titers above 65IU/ml for anti-TPO and 120IU/ml for TgAb. Additional data from thyroid ultrasonography were collected and showed that cases of NIFTP without association with HT, presented nodules ranging from 1.5 cm to 5.1 cm, predominantly hypoechoic, solid, with regular contours, peripheral vascularization and located predominantly in the right lobe. In conclusion, 14 cases of NIFTP were detected, among 232 cases of PTC, with 6 cases being histologically associated with HT. Of these, 5 cases had laboratory tests with positive antithyroid antibody titers, proving this association, from a clinical point of view. All cases of NIFTP with and without HT association were female, with nodules ranging from 0.3cm to 5.0cm to ultrasound, predominantly in the right lobe.

Diffuse Large B-cell Lymphoma of thyroid gland in an Adolescent girl with Hashimoto’s thyroiditis

2020 ◽  
Author(s):  
Mara Xatzipsalti ◽  
Evangelos Bourousis ◽  
Maria Nikita ◽  
Myrsini Gkeli ◽  
Evgenia Magkou ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
B Cell ◽  
Hashimoto’S Thyroiditis ◽  
Adolescent Girl ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Hashimoto's Thyroiditis ◽  
Large B Cell Lymphoma ◽  
Large B Cell

scholarly journals Thyroid Carcinoma on the Side of the Absent Lobe in a Patient with Thyroid Hemiagenesis

2017 ◽  
Vol 2017 ◽  
pp. 1-5
Author(s):  
Hiroki Sato ◽  
Kiyoaki Tsukahara ◽  
Ray Motohashi ◽  
Midori Wakiya ◽  
Hiromi Serizawa ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Papillary Carcinoma ◽  
Thyroid Tissue ◽  
Needle Aspiration ◽  
Left Lobe ◽  
Thyroid Hemiagenesis ◽  
Poorly Differentiated ◽  
Node Metastases ◽  
Right Lobe ◽  
The Right

Background. Thyroid carcinoma complicated by hemiagenesis is very rare, and previous reports have not described this cancer on the side of the absent lobe. Methods and Results. We report the case of a 64-year-old woman in whom left thyroid hemiagenesis was discovered incidentally during investigations of abnormal sensation during swallowing. A tumorous 1.4 cm lesion was also found on the side of the absent lobe, left of the isthmus. Fine-needle aspiration biopsy revealed class V papillary carcinoma, but no lymph node metastases. Total thyroidectomy was performed for stage cT1bN0M0 carcinoma. Histopathology revealed normal thyroid tissues in the right lobe and isthmus, while the left lobe was absent. The mostly papillary carcinoma was adjacent to the truncated thyroid tissue, with a portion histologically consistent with poorly differentiated carcinoma. Conclusions. All previously reported cases of thyroid cancer complicated by hemiagenesis have represented carcinoma occurring within the present lobe. This case is extremely rare.

Acute thyroiditis after tooth extraction

1935 ◽  
Vol 31 (3-4) ◽  
pp. 535-535
Author(s):  
E. Auslender
Keyword(s):  
Thyroid Gland ◽  
Tooth Extraction ◽  
Acute Inflammation ◽  
Right Lobe ◽  
The Right ◽  
Acute Thyroiditis

Five days after tooth extraction, a 24-year-old woman developed acute inflammation of the right lobe of the thyroid gland, which after a while spontaneously healed.

scholarly journals Leydig cell tumor of the testis: an incidental finding at 18F-FDG PET/CT imaging

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
Almalki Yassir
Keyword(s):  
Leydig Cell ◽  
Fdg Pet ◽  
Chronic Rejection ◽  
Ct Imaging ◽  
The Body ◽  
Whole Body ◽  
Pet Ct ◽  
18F Fdg ◽  
The Right ◽  
Fdg Pet Ct

Abstract Background Leydig cell tumors (LCTs) represent the most common form of stromal tumors. We reported the 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) findings of a patient with testicular LCT. Case presentation A 50-year-old man with a history of end-stage renal disease and renal transplantation 19 years ago. One year earlier, he started to have a chronic rejection. During the investigation to determine the cause of chronic rejection, a suspicious lesion in the graft with a collection around it was seen on ultrasound (US) images, raising the possibility of post-transplant lymphoproliferative disorder (PTLD). The patient was referred for further evaluation by whole body 18F-FDG PET/CT imaging. The image finding revealed an incidental hypermetabolic focal lesion in the right testicle—no other specific findings in the remaining parts of the body nor definitive FDG avid lymphadenopathy to suggest PTLD. Testicular US was requested and showed a well-defined right-sided heterogeneous hypoechoic intratesticular focal mass at the upper pole of the right testis with significant internal vascularity on the color Doppler imaging. The patient underwent a right radical orchidectomy, and the tumor was pathologically confirmed as an LCT. Conclusion In our case, 18F-FDG-PET/CT has been helpful in incidentally detecting this rare testicular tumor in a patient with suspected PTLD.

Rectal carcinoma metastatic to the thyroid gland

1996 ◽  
Vol 110 (2) ◽  
pp. 192-195 ◽  
Author(s):  
Thomas W. Mesko ◽  
Julie Friedman ◽  
Harry Sendzischew ◽  
Daniel D. Nixon
Keyword(s):  
Thyroid Gland ◽  
Rectal Carcinoma ◽  
Secondary Malignancy ◽  
Prior History ◽  
Low Back ◽  
Metastatic Adenocarcinoma ◽  
History Of ◽  
Right Lobe ◽  
The Right ◽  
History Of Cancer

AbstractClinically evident metastases to the thyroid gland are rarely found antemortem. A case of a 59-year-old woman with a history of rectal carcinoma, who presented with low back pain and a mass in the right lobe of her thyroid gland, is presented. The tumour of the thyroid was found to be metastatic adenocarcinoma from her previous rectal cancer. Other synchronous metastases were noted in her lumbar spine and kidneys.The clinical finding of metastases to the thyroid gland is rare, particularly from a colorectal primary. One must consider, however, the possibility of a tumour of the thyroid gland representing a secondary malignancy in any patient with a prior history of cancer.

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