scholarly journals Effect of coffee reduction on constituent concentration in an energy-efficient process of ultrasonic extraction

2015 ◽  
Vol 19 (4) ◽  
pp. 1373-1377
Author(s):  
Cheng-Chi Wang ◽  
Shane-Rong Sheu ◽  
Her-Terng Yau ◽  
Ming-Jyi Jang
Keyword(s):  
Energy Efficient ◽  
High Performance ◽  
Extraction Process ◽  
Manufacturing Cost ◽  
Negative Results ◽  
Ultrasonic Process ◽  
Oxidation Resistant ◽  
Artery Disease ◽  
Save Energy ◽  
The Brain

Coffee is one of the popular beverage; its constituents include caffeine, oxidation resistant aromatic constituents, protein, tannin, and fat. It is indicated in literatures that a proper amount of coffee stimulates the brain and enhances memory, but excessive coffee causes negative results, such as coronary artery disease, high blood pressure, heart disease and kidney disease. This study used high-performance ultrasonic process to discuss the effect of pulverized coffee reduction on the constituent concentration. It further compared the constituent concentrations obtained in different extraction periods. The experimental results show that the coffee aroma constituents can be extracted effectively by ultrasonic process without any organic solvent, and the constituent concentration does not decrease with the addition of pulverized coffee. Therefore, the consumption of pulverized coffee can be reduced greatly by using the proposed. The time of extraction process can be shortened, so as to save energy. The most important point is to reduce the enterprises manufacturing cost and to increase the profit.

scholarly journals APPLICATION OF THE ULTRASONIC GENERATOR IN THE EXTRACTOR AND DETERMINATION OF ITS ENERGY CONSUMPTION

2020 ◽  
Vol 2021 (1) ◽  
pp. 55-62
Author(s):  
Shaxnoza Sultanova ◽  
◽  
Jasur Safarov ◽  
Azamat Usenov ◽  
Doston Samandarov
Keyword(s):  
Energy Consumption ◽  
Energy Efficient ◽  
High Performance ◽  
Extraction Process ◽  
Flow Time ◽  
Volume Curve ◽  
Complete Extraction ◽  
Time Required ◽  
Solvent Flow

An ultrasonic generator was used in the Soxhlet extractor. To evaluate the process, the solvent flow was examined. The influence of the flow time in the Soxhlet on the process was analyzed. The formula for the residence time of streaming particles in the apparatus is given. A standardized volume curve V was formed. The time required for the solvent to remain in the apparatus is important during the extraction process. The description of the structure of flows of mass metabolic processes also means that it allows you to determine the movement and distribution of substances in these flows. Therefore, we wrote a hydrodynamic model of flows in the Soxhlet in the form of equations that represent the change in time in the apparatus. Ways to accelerate the extraction process are considered. The advantages of each method have been explored. Ultrasonic acceleration was selected from the investigated method. The parameters of the generator for generating ultrasound are considered. A compatible generator was selected. Selected “High Power Ultrosonic Generator” 40 kHz, 1.2 kW because it uses less power and does not affect the balance of the device. If a generator with high parameters is selected, the effect on the balance of the device is determined. For large extractors, a high-performance ultrasonic generator is recommended. The schematic diagram of the selected generator is taken from the reference book. We have performed a complete extraction process to estimate the energy consumption of the process. It turned out that the process, carried out with the help of ultrasound, is fast and energy efficient. The experiments took over an hour to evaluate the process. While 10 ml of the substance was extracted from the extracted basil leaf for one hour, 15 ml of the substance was separated from the addition process by sonication for one hour. In each experiment, the mode was chosen the same. Graphs were drawn to compare the results.

Challenges And Energy Efficient Techniques For High Performance Wireless Communications

2015 ◽  
Vol 1 (4) ◽  
pp. 1-12
Author(s):  
Chidadala Janardhan ◽  
◽  
Bhagath Pyda ◽  
J. Manohar ◽  
K. V. Ramanaiah ◽  
...  
Keyword(s):  
Wireless Communications ◽  
Energy Efficient ◽  
High Performance

Long-term management of patients with multiple brain metastases after shaped beam radiosurgery

2004 ◽  
pp. 406-412
Author(s):  
Paul Okunieff ◽  
Michael C. Schell ◽  
Russell Ruo ◽  
E. Ronald Hale ◽  
Walter G. O'Dell ◽  
...  
Keyword(s):  
Brain Metastases ◽  
Tumor Control ◽  
Content Type ◽  
Negative Results ◽  
Multiple Metastases ◽  
Extracranial Disease ◽  
Successful Control ◽  
The Brain

✓ The role of radiosurgery in the treatment of patients with advanced-stage metastatic disease is currently under debate. Previous randomized studies have not consistently supported the use of radiosurgery to treat patients with numbers of brain metastases. In negative-results studies, however, intracranial tumor control was high but extracranial disease progressed; thus, patient survival was not greatly affected, although neurocognitive function was generally maintained until death. Because the future promises improved systemic (extracranial) therapy, the successful control of brain disease is that much more crucial. Thus, for selected patients with multiple metastases to the brain who remain in good neurological condition, aggressive lesion-targeting radiosurgery should be very useful. Although a major limitation to success of this therapy is the lack of control of extracranial disease in most patients, it is clear that well-designed, aggressive treatment substantially decreases the progression of brain metastases and also improves neurocognitive survival. The authors present the management and a methodology for rational treatment of a patient with breast cancer who has harbored 24 brain metastases during a 3-year period.

Pharmacokinetics and Tissue Distribution Study of Ferruginol in Wistar Rat by High-performance Liquid Chromatography

2018 ◽  
Vol 15 (1) ◽  
pp. 67-73 ◽  
Author(s):  
Guiyun Cao ◽  
Suqiao Han ◽  
Keke Li ◽  
Li Shen ◽  
Xiaohong Wang ◽  
...  
Keyword(s):  
Tissue Distribution ◽  
Mobile Phase ◽  
High Performance ◽  
Wistar Rat ◽  
Freezing And Thawing ◽  
Promising Candidate ◽  
Distribution Study ◽  
Substance Loss ◽  
Tissue Distribution Study ◽  
The Brain

Background: Ferruginol (FRGN) exhibits a broad range of pharmacological properties which make it a promising candidate for chemoprevention. However, little is known about its absorption, distribution, metabolism, excretion, and toxicity (ADMET) properties. Methods: A rapid, sensitive and specific HPLC-DAD method was established to quantify FRGN in the plasma and tissues of Wistar rats. After extraction of FRGN with ethyl acetate (EtOAc), chromatographic separation was performed on a YMC ODS C18 column (250 × 4.6 mm I.D., 5 µm) with a mobile phase consisting of methanol-water (92:8, v/v) at a flow rate of 0.9 mL/min. Detection was conducted with a wavelength of 273 nm at 25 °C. Results: The calibration curves for FRGN were linear in the concentration range of 0.5-20 µg/mL for plasma, 0.5-10 µg/mL for heart, liver, spleen, lung, kidney, stomach, intestine, brain and muscle. After three cycles of freezing and thawing, the concentration variations were within ± 7% of nominal concentrations, indicating no significant substance loss during repeated thawing and freezing. The assay was applied to pharmacokinetic and tissue distribution study in rats. Results suggested that lung, heart, liver, spleen and kidney were the major distribution tissues of FRGN in rats, and FRGN could permeate the blood-brain barrier to distribute in the brain of rats. Conclusion: The information provided by this research is very useful for gaining knowledge of the pharmacokinetic process and tissue distribution of FRGN.

scholarly journals A novel PET tracer 18F-deoxy-thiamine: synthesis, metabolic kinetics, and evaluation on cerebral thiamine metabolism status

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Changpeng Wang ◽  
Siwei Zhang ◽  
Yuefei Zou ◽  
Hongzhao Ma ◽  
Donglang Jiang ◽  
...  
Keyword(s):  
High Performance ◽  
Specific Activity ◽  
High Accumulation ◽  
Metabolic Kinetics ◽  
Thiamine Metabolism ◽  
Pet Tracer ◽  
The Status ◽  
The Brain

Abstract Background Some neuropsychological diseases are associated with abnormal thiamine metabolism, including Korsakoff–Wernicke syndrome and Alzheimer’s disease. However, in vivo detection of the status of brain thiamine metabolism is still unavailable and needs to be developed. Methods A novel PET tracer of 18F-deoxy-thiamine was synthesized using an automated module via a two-step route. The main quality control parameters, such as specific activity and radiochemical purity, were evaluated by high-performance liquid chromatography (HPLC). Radiochemical concentration was determined by radioactivity calibrator. Metabolic kinetics and the level of 18F-deoxy-thiamine in brains of mice and marmosets were studied by micro-positron emission tomography/computed tomography (PET/CT). In vivo stability, renal excretion rate, and biodistribution of 18F-deoxy-thiamine in the mice were assayed using HPLC and γ-counter, respectively. Also, the correlation between the retention of cerebral 18F-deoxy-thiamine in 60 min after injection as represented by the area under the curve (AUC) and blood thiamine levels was investigated. Results The 18F-deoxy-thiamine was stable both in vitro and in vivo. The uptake and clearance of 18F-deoxy-thiamine were quick in the mice. It reached the max standard uptake value (SUVmax) of 4.61 ± 0.53 in the liver within 1 min, 18.67 ± 7.04 in the kidney within half a minute. The SUV dropped to 0.72 ± 0.05 and 0.77 ± 0.35 after 60 min of injection in the liver and kidney, respectively. After injection, kidney, liver, and pancreas exhibited high accumulation level of 18F-deoxy-thiamine, while brain, muscle, fat, and gonad showed low accumulation concentration, consistent with previous reports on thiamine distribution in mice. Within 90 min after injection, the level of 18F-deoxy-thiamine in the brain of C57BL/6 mice with thiamine deficiency (TD) was 1.9 times higher than that in control mice, and was 3.1 times higher in ICR mice with TD than that in control mice. The AUC of the tracer in the brain of marmosets within 60 min was 29.33 ± 5.15 and negatively correlated with blood thiamine diphosphate levels (r = − 0.985, p = 0.015). Conclusion The 18F-deoxy-thiamine meets the requirements for ideal PET tracer for in vivo detecting the status of cerebral thiamine metabolism.

scholarly journals Thread Batching for High-performance Energy-efficient GPU Memory Design

2019 ◽  
Vol 15 (4) ◽  
pp. 1-21
Author(s):  
Bing Li ◽  
Mengjie Mao ◽  
Xiaoxiao Liu ◽  
Tao Liu ◽  
Zihao Liu ◽  
...  
Keyword(s):  
Energy Efficient ◽  
High Performance ◽  
Memory Design

scholarly journals Effects of Steel Fiber Percentage and Aspect Ratios on Fresh and Harden Properties of Ultra-High Performance Fiber

2021 ◽  
Vol 2 (3) ◽  
pp. 501-515
Author(s):  
Rajib Kumar Biswas ◽  
Farabi Bin Ahmed ◽  
Md. Ehsanul Haque ◽  
Afra Anam Provasha ◽  
Zahid Hasan ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Aspect Ratio ◽  
High Performance ◽  
Steel Fiber ◽  
Setting Time ◽  
Fiber Reinforced Concrete ◽  
Future Research ◽  
Manufacturing Cost ◽  
Aspect Ratios ◽  
High Performance Fiber

Steel fibers and their aspect ratios are important parameters that have significant influence on the mechanical properties of ultrahigh-performance fiber-reinforced concrete (UHPFRC). Steel fiber dosage also significantly contributes to the initial manufacturing cost of UHPFRC. This study presents a comprehensive literature review of the effects of steel fiber percentages and aspect ratios on the setting time, workability, and mechanical properties of UHPFRC. It was evident that (1) an increase in steel fiber dosage and aspect ratio negatively impacted workability, owing to the interlocking between fibers; (2) compressive strength was positively influenced by the steel fiber dosage and aspect ratio; and (3) a faster loading rate significantly improved the mechanical properties. There were also some shortcomings in the measurement method for setting time. Lastly, this research highlights current issues for future research. The findings of the study are useful for practicing engineers to understand the distinctive characteristics of UHPFRC.

A novel high-performance and energy-efficient RRAM device with multi-functional conducting nanofilaments

Nano Energy ◽  
2021 ◽  
Vol 82 ◽  
pp. 105717
Author(s):  
Min-Ci Wu ◽  
Jui-Yuan Chen ◽  
Yi-Hsin Ting ◽  
Chih-Yang Huang ◽  
Wen-Wei Wu
Keyword(s):  
Energy Efficient ◽  
High Performance

High performance self-heated membrane distillation system for energy efficient desalination process

2021 ◽  
Author(s):  
Wei-Song Hung ◽  
Subrahmanya T M ◽  
Po Ting Lin ◽  
Yu-Hsuan Chiao ◽  
Januar Widakdo ◽  
...  
Keyword(s):  
Environmental Pollution ◽  
Energy Efficient ◽  
High Performance ◽  
Membrane Distillation ◽  
Energy Crisis ◽  
Safe Water ◽  
Global Challenges ◽  
Promising Strategy ◽  
Distillation System

Membrane distillation (MD) based desalination process is thought to be a promising strategy to address global challenges such as safe water-energy crisis and environmental pollution. Here, we demonstrate a novel...

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