scholarly journals Small bowel adenocarcinoma mimicking a large adrenal tumor

2013 ◽  
Vol 141 (3-4) ◽  
pp. 232-236
Author(s):  
Miomira Ivovic ◽  
Vladan Zivaljevic ◽  
Svetlana Vujovic ◽  
Ljiljana Marina ◽  
Milina Tancic-Gajic ◽  
...  
Keyword(s):  
Small Bowel ◽  
Correct Diagnosis ◽  
Proximal Jejunum ◽  
Small Bowel Adenocarcinoma ◽  
Large Tumor ◽  
Urinary Catecholamines ◽  
Endoscopic Techniques ◽  
Acute Peritonitis ◽  
Abdominal Symptoms ◽  
Small Bowel Carcinoma

Introduction. Adenocarcinoma of the small bowel is a rare gastrointestinal neoplasm usually affecting the distal duodenum and proximal jejunum. Because of their rarity and poorly defined abdominal symptoms, a correct diagnosis is often delayed. Case Outline. We present a 43-year-old woman admitted at the Clinic for Endocrinology due to a large tumor (over 7 cm) of the left adrenal gland. The tumor was detected by ultrasound and confirmed by CT scan. The patient complained of abdominal pain in the left upper quadrant, fatigue and septic fever. Normal urinary catecholamines excluded pheochromocytoma. The endocrine evaluations revealed laboratory signs of subclinical hypercorticism: midnight cortisol 235 nmol/L, post 1 mg - overnight Dexamethasone suppression test for cortisol 95.5 nmol/L and basal ACTH 4.2 pg/mL. Plasma rennin activity and aldosterone were within the normal range. Surgery was performed. Intraoperative findings showed signs of acute peritonitis and a small ulceration of the jejunum below at 70 cm on the anal side from the Treitz?s ligament. Adrenal glands were not enlarged. Patohistology and immunochemistry identified adenocarcinoma of the jejunum without infiltration of the lymphatic nodules. The extensive jejunal resection and lavage of the peritoneum were performed. Due to complications of massive peritonitis, the patient died seven days after surgery. Conclusion. Poorly defined symptoms and a low incidence make the diagnosis of small bowel carcinoma, particularly of the jejunal region, very difficult in spite of the new endoscopic techniques.

scholarly journals Increased Incidence of Second Malignancies Associated with Small Bowel Adenocarcinoma

1997 ◽  
Vol 11 (1) ◽  
pp. 65-68 ◽  
Author(s):  
Dianne Ripley ◽  
Brian H Weinerman
Keyword(s):  
Small Bowel ◽  
The Elderly ◽  
Bowel Cancer ◽  
Small Bowel Adenocarcinoma ◽  
Second Malignancies ◽  
Small Bowel Cancer ◽  
Unstable Gene ◽  
Small Bowel Carcinoma ◽  
Canadian Provinces ◽  
Or Genes

BACKGROUND:Some data suggest that there is an increased incidence of second malignancies associated with small bowel adenocarcinomas, but this has not been reviewed in the context of a tumour registry.OBJECTIVE:To review tumour registries based on population statistics to determine whether there is an increased incidence of second malignancies associated with small bowel adenocarcinomas.METHODS:The authors reviewed the tumour registries of two Canadian provinces (British Columbia and Manitoba) for small bowel adenocarcinoma to determine whether an increase in associated malignancies existed compared with those expected in the respective populations.RESULTS:A greater than eightfold increase in second malignancies was associated with small bowel carcinoma. The majority (73%) occurred before the diagnosis of the small bowel malignancy. Twenty-nine per cent were associated with cancers of the colon, rectum or both.CONCLUSIONS:There is an increased association of malignancy and the diagnosis of small bowel cancer. Generally, small bowel cancer is the second malignancy to be diagnosed, and the diagnosis is most often made in the elderly. Does this represent a syndrome related to an unstable gene (or genes) or a lack of repair, which makes individuals susceptible to this malignancy as they age?

Primary adenocarcinoma of the ileum causing obstruction in an 84-year-old patient – a case report

Nowa Medycyna ◽  
2018 ◽  
Vol 25 (4) ◽  
Author(s):  
Krzysztof Łampika ◽  
Paweł Dutkiewicz ◽  
Przemysław Ciesielski
Keyword(s):  
Case Report ◽  
Small Bowel ◽  
Early Stage ◽  
Tumour Progression ◽  
Correct Diagnosis ◽  
Primary Adenocarcinoma ◽  
Intestinal Fistula ◽  
Small Bowel Adenocarcinoma ◽  
Early Stage Disease ◽  
Stage Disease

Although small bowel adenocarcinoma is a rare cancer, with estimated incidence rate of 4 cases per million persons it is the most common small bowel tumour. Diagnosis of early-stage disease is difficult due to non-specific symptoms. Patients are usually treated on an emergency basis due to gastrointestinal obstruction or bleeding. The paper presents a case report of an 84-year-old female who underwent surgical treatment due to bowel obstruction caused by ileum cancer, and in whom diagnostic imaging did not allow for a correct diagnosis. The surgery was complicated by intestinal fistula. Histopathology confirmed local tumour progression. After treatment completion, the patient was referred for further anti-cancer treatment.

scholarly journals Coexistence of gastrointestinal stromal tumor of the stomach and small bowel adenocarcinoma: A case report

2021 ◽  
Vol 38 (3) ◽  
pp. 393-395
Author(s):  
Talat AYYILDIZ ◽  
İbrahim GÖNEN ◽  
Beytullah YILDIRIM ◽  
Kağan KARABULUT ◽  
Filiz KARAGÖZ ◽  
...  
Keyword(s):  
Small Bowel ◽  
English Language ◽  
Simultaneous Occurrence ◽  
Malignant Neoplasms ◽  
Gastric Gist ◽  
Positive Staining ◽  
Proximal Jejunum ◽  
Small Bowel Adenocarcinoma ◽  
First Case ◽  
The Masses

The coexistence of gastrointestinal tumors (GIST’s) with other several primary malignant neoplasms has been demonstrated. However, there is no study that reported simultaneous occurrence of primary small bowel adenocarcinoma (SBA) and a GIST located in the stomach. Here, we report the first case of SBA and a synchronous gastric GIST. Surgical resection and clinicopathological characterization were performed for the masses identified through endoscopic and radiologic studies. Computed tomography scan showed a 13 mm mass located at the gastric antrum and another mass lesion partially occluding the jejunum. A biopsy specimen was obtained from the mass at the proximal jejunum by enteroscopy. The tumor was reported as adenocarcinoma. The patient was operated by the general surgery team. The features of the submucosal lesion resected from the antrum were consistent with a diagnosis of a GIST which contained spindle cells and showed positive staining with CD-117 and CD-34. Mitosis was not observed and Ki67 index was below 10%. This is the first case of coexistence of GIST of the stomach and SBA to be reported in English-language literature. The prominent characteristics of our case include its antral localization, male sex, absence of mitosis and incidental diagnosis.

Prognostic relevance of programmed death-ligand 1 expression and microsatellite status in small bowel adenocarcinoma

2020 ◽  
Vol 55 (3) ◽  
pp. 321-329
Author(s):  
Johannes Klose ◽  
Felix Lasitschka ◽  
Cornelia Horsch ◽  
Moritz J. Strowitzki ◽  
Thomas Bruckner ◽  
...  
Keyword(s):  
Small Bowel ◽  
Small Bowel Adenocarcinoma ◽  
Programmed Death Ligand 1 ◽  
Prognostic Relevance ◽  
Programmed Death

Metastatic Ovarian Tumors Originating From a Small Bowel Adenocarcinoma – A Case Report and Brief Literature Review

2017 ◽  
Vol 36 (3) ◽  
pp. 253-260 ◽  
Author(s):  
Junji Mitsushita ◽  
Sachiho Netsu ◽  
Koichi Suzuki ◽  
Mitsuhiro Nokubi ◽  
Akira Tanaka
Keyword(s):  
Case Report ◽  
Small Bowel ◽  
Literature Review ◽  
Ovarian Tumors ◽  
Small Bowel Adenocarcinoma

Primary Small Bowel Adenocarcinoma Presenting as a Malignant Ovarian Neoplasm

1985 ◽  
Vol 150 (2) ◽  
pp. 105-106 ◽  
Author(s):  
D. G. Gallup ◽  
R. J. Stock ◽  
J. J. Sammons ◽  
W. E. Paulk
Keyword(s):  
Small Bowel ◽  
Ovarian Neoplasm ◽  
Small Bowel Adenocarcinoma ◽  
Primary Small Bowel

scholarly journals Relationship between MRI quantified small bowel motility and abdominal symptoms in Crohn’s disease patients—a validation study

2018 ◽  
pp. 20170914 ◽  
Author(s):  
Ruaridh M Gollifer ◽  
Alex Menys ◽  
Jesica Makanyanga ◽  
Carl AJ Puylaert ◽  
Frans M Vos ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Small Bowel ◽  
Crohn's Disease ◽  
Validation Study ◽  
Bowel Motility ◽  
Small Bowel Motility ◽  
Abdominal Symptoms
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