scholarly journals Actinomycosis of the caecum simulating carcinoma in a patient with a long-term intrauterine device

2009 ◽  
Vol 137 (5-6) ◽  
pp. 285-287 ◽  
Author(s):  
Radoje Colovic ◽  
Nikica Grubor ◽  
Marjan Micev ◽  
Stojan Latincic ◽  
Slavko Matic ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Intrauterine Device ◽  
Right Hemicolectomy ◽  
Bacteriological Examination ◽  
Ascending Colon ◽  
Vaginal Secretion ◽  
Chron's Disease ◽  
Irregular Form ◽  
Localized Disease

Introduction. Actinomycosis of the caecum is a rare, but most frequently an abdominally localized disease. It often simulates inflammatory malignancy, rarely a periappendicular abscess or Chron's disease and is only exceptionally the cause of intestinal obstruction or bleeding. Case Outline. The authors present a 35-year-old woman with an intrauterine device which remained inserted for over three years, causing the development of pain, fever, vaginal secretion and bleeding that continued even after the device was removed. Ultrasonography showed a tumorous mass of irregular form located close to the uterus, which after a few months developed into a colliquation filled with pus requiring incision. Bacteriological examination failed to show actinomycosis. Due to the tumorous lesions involving the terminal ileum, appendix, caecum, ascending colon and omentum, a right hemicolectomy was performed. Based on histolopathological findings of the resected sample the diagnosis of actinomycosis was made. Therefore, after surgery the patient began treatment with antibiotics resulting in full recovery. Conclusion. Although rare, actinomycosis of the caecum should be taken into consideration in the differential diagnosis of tumorous lesions of the caecoascending part of the colon, particularly if the tumour is associated with inflammation.

Toxoplasma Appendicitis: A Once-in-a-Lifetime Diagnosis!

2017 ◽  
Vol 26 (1) ◽  
pp. 89-92 ◽  
Author(s):  
Anisha M. Fernandes ◽  
Maheshkumar M. Lakhe ◽  
Sanjay A. Pai
Keyword(s):  
Differential Diagnosis ◽  
Acute Appendicitis ◽  
Muscularis Propria ◽  
Immunocompromised Patients ◽  
Lymphoid Follicles ◽  
Negative Results ◽  
Immunosuppressed Patients ◽  
Life Threatening

Toxoplasmosis is generally asymptomatic in immunocompetent individuals, but it can be life-threatening in immunocompromised patients. We present a case of a 62-year-old man with clinical features of acute appendicitis. Histology showed a transmural infiltrate of eosinophils. In addition, there were reactive lymphoid follicles with histiocytes in the submucosa and tachyzoites in the muscularis propria. Immunohistochemistry confirmed the diagnosis of toxoplasma appendicitis. Serological evaluation yielded negative results. Retrospective review of the history revealed that the patient was on long-term immunosuppressive therapy with methotrexate. The patient was treated with sulfamethoxazole-trimethoprim and is asymptomatic at 7-month follow-up. Toxoplasma appendicitis must be considered in the differential diagnosis of appendicitis in immunosuppressed patients.

THE CLASSIC TYPE OF EHLERS–DANLOS SYNDROME: DIFFERENTIAL DIAGNOSIS AND PECULIARITIES OF PATIENT MANAGEMENT

2021 ◽  
Vol 100 (5) ◽  
pp. 62-69
Author(s):  
А.N. Semyachkina ◽  
◽  
E.А. Nikolaeva ◽  
А.R. Zabrodina ◽  
L.P. Melikyan ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Adult Population ◽  
Gene Mutations ◽  
Hereditary Disease ◽  
Ehlers Danlos Syndrome ◽  
Severe Pathology ◽  
Type V ◽  
Danlos Syndrome

The Classic Ehlers–Danlos syndrome (cEDS) is an autosomal dominant hereditary disease caused by type V collagen defect. The incidence of pathology is estimated at 1:20,000 of the population. The results of a long-term (15 years) follow-up of a group of patients (n=18) with cEDS, including 5 boys and 13 girls aged from 3 to 18 years, are presented. The diagnosis was made based on the presence of 2 large and 5 small international diagnostic criteria in all patients. The progreduated character of the disease is shown, which is most obvious in the dynamics of the state of the musculoskeletal system. Genetic verification of the diagnosis was performed in 6 patients; 5 probands had mutations in the COL5A1 gene, and one in the COL5A2 gene. Mutations already registered in the database were detected only in 2 children. Previously unknown substitutions were found in 4 patients. The article presents the issues of differential diagnosis of this severe pathology and touches upon the issue of continuity between medical pediatric specialists and doctors of various specialties working with the adult population.

scholarly journals Long term survival after right hemicolectomy and pancreatoduodenectomy for locally advanced colonic cancer: Case report

2011 ◽  
Vol 2 (7) ◽  
pp. 206-207 ◽  
Author(s):  
Iraklis Perysinakis ◽  
Alexander Nixon ◽  
Aggeliki Katopodi ◽  
Emmanouil Tzirakis ◽  
Despoina Georgiadou ◽  
...  
Keyword(s):  
Case Report ◽  
Colonic Cancer ◽  
Locally Advanced ◽  
Right Hemicolectomy ◽  
Cancer Case ◽  
Term Survival ◽  
Long Term Survival ◽  
Advanced Colonic Cancer

Benign Paroxysmal Vertigo of Childhood: A Long-Term Follow-Up

Cephalalgia ◽  
1994 ◽  
Vol 14 (6) ◽  
pp. 458-460 ◽  
Author(s):  
G Lanzi ◽  
U Balottin ◽  
E Fazzi ◽  
M Tagliasacchi ◽  
M Manfrin ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Age Of Onset ◽  
Clinical Aspects ◽  
Migrainous Vertigo ◽  
Long Term Follow Up

We examined clinical aspects of Benign Paroxysmal Vertigo (BPV) in infancy and its most frequent differential diagnosis, in particular analogies and differences with forms of “migrainous vertigo” (MV) of later onset. During a long-term follow-up of 7 cases of BPV, diagnosed according to the Basser criteria, 5 of 7 BPV cases spontaneously resolved and 6 of 7 patients later developed migraine and other migraine-related symptoms. This course differs from that described for MV only in the age of onset of headache and in the chronological relationship with vertigo. The authors suggest that BPV can be interpreted as a migraine precursor and MV as a migraine equivalent.

MALIGNANT LYMPHOMA IN CHILDREN

PEDIATRICS ◽  
1961 ◽  
Vol 28 (6) ◽  
pp. 985-992
Author(s):  
Richard J. Bailey ◽  
E. Omer Burgert ◽  
David C. Dahlin
Keyword(s):  
Follicular Lymphoma ◽  
Malignant Lymphoma ◽  
Hodgkin's Disease ◽  
Radiation Treatment ◽  
Hodgkin’S Disease ◽  
Effective Means ◽  
Surgical Removal ◽  
Term Survival ◽  
Localized Disease

On the basis of observations made on 76 children with malignant lymphoma, of whom 28 had Hodgkin's disease (25 with Hodgkin's granuloma and 3 with Hodgkin's sarcoma) and 48 had lymphosarcoma, the following conclusions are drawn: Hodgkin's granuloma has a fairly prolonged course in childhood with a relatively good outlook for 5-year survival, but late recurrences are more common than in the lymphosarcoma group. Lymphosarcoma, excluding giant follicular lymphoma, has a more rapidly malignant course than does Hodgkin's granuloma, but long-term survival does occur in instances of localized disease involving the peripheral nodes on the small intestine. Chemotherapy and radiation therapy provide effective means for controlling Hodgkin's disease and giant follicular lymphoma, even when disease is widespread. Localized disease, when it occurs in malignant lymphoma, requires vigorous radiation treatment. In selected cases, radical surgical removal prior to radiation is indicated. The outlook for these patients is good.

Procalcitonin as a diagnostic marker of infections and inflammation

2018 ◽  
Vol 54 (3) ◽  
pp. 179-184
Author(s):  
Weronika Kolasińska ◽  
Agnieszka Jankowska-Kulawy
Keyword(s):  
Differential Diagnosis ◽  
Clinical Practice ◽  
Systemic Inflammatory Response Syndrome ◽  
Inflammatory Response ◽  
Viral Infections ◽  
Diagnostic Marker ◽  
Systemic Inflammatory Response ◽  
Clinical Algorithms

Infections are quite common, especially in long-term hospitalized patients. Eearly differential diagnosis of severe bacterial and viral infections in patients in severe or critical condition is particularly important. Procalcitonin is a good and, above all, early marker of sepsis and generalized inflammatory states. 85% sensitivity and 91% specificity of this study were shown in the differentiation patients with systemic inflammatory response syndrome noninfectious and sepsis defined as a systemic inflammatory response syndrome induced by infection. The usage of procalcitonin assays in clinical algorithms may accelerate the diagnosis of infectious conditions, reduce the abuse of antibiotics and optimize therapy with these drugs. Therefore, the determination of procalcitonin concentration is increasingly used in clinical practice.

Brain Tumors

2020 ◽  
pp. 23-42
Author(s):  
Angela M. Bohnen ◽  
Kaisorn L. Chaichana ◽  
Alfredo Quinones-Hinojosa
Keyword(s):  
Differential Diagnosis ◽  
Brain Tumors ◽  
Demyelinating Disease ◽  
Intraoperative Complications ◽  
Postoperative Management ◽  
Treatment Modalities ◽  
Adjuvant Radiation ◽  
Term Care ◽  
Metastatic Lesions

Having a general understanding of brain tumors is integral to mastering the oral board examination. For the general session, examinees should be able to identify both intra-axial and extra-axial tumors and provide a comprehensive understanding of the differential diagnosis and plan regarding treatment, while also verbalizing concepts behind the treatment modalities and articulating to a patient and family the alternative approaches as well as the complications related to management. Pathologies to familiarize oneself with include gliomas, meningiomas, metastatic lesions, and pituitary lesions. For subspecialty examinees, complex cases such as endonasal, endoscopic, keyhole, and skull base approaches should be mastered. For each case, a broad differential diagnosis should include infection, hematoma, infarction, thrombosed aneurysm, inflammation, and/or demyelinating disease. Discuss the preoperative workup the indications for surgery and surgical approach. Interpret the preoperative and postoperative imaging critically. Be prepared for potential intraoperative complications and discussion of postoperative management including adjuvant radiation and chemotherapy and long-term care.

scholarly journals Localized and indolent myeloma

Blood ◽  
1980 ◽  
Vol 56 (3) ◽  
pp. 521-525 ◽  
Author(s):  
R Alexanian
Keyword(s):  
Multiple Myeloma ◽  
Bone Lesions ◽  
Term Outcome ◽  
Myeloma Protein ◽  
Long Term Outcome ◽  
Long Term Follow Up ◽  
Tumor Load ◽  
Localized Disease

Abstract Criteria were defined for recognizing 29 patients with a localized plasmacytoma of bone and 20 patients with an indolent variety of multiple myeloma in order to justify long-term follow-up without chemotherapy. All patients with indolent myeloma were asymptomatic from their low tumor mass disease, had a hemoglobin greater than 10 g/dl, and showed no more than 3 lytic bone lesions. The presence of more than 200 mg/day of Bence Jones protein was usually followed by disease progression within 2 yr. Serial assessments of myeloma protein level provided a useful index of changing tumor load and the need for chemotherapy. In patients with localized disease, radiotherapy usually reduced myeloma proteins markedly with subsequent disease control for many years, even though small serum peaks persisted. Chemotherapy for multiple myeloma was not required for a median of 8 yr in patients presenting with localized disease and of 3 yr in those with indolent myeloma. The additional survival from the start of drug treatment was similar to that of comparable patients treated promptly for overt multiple myeloma. The delay of chemotherapy until evidence of tumor progression did not affect the long-term outcome of patients with localized or indolent myeloma.

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