scholarly journals Biodentinetm as a furcal perforation repair material: A case series

2017 ◽  
Vol 70 (7-8) ◽  
pp. 223-225 ◽  
Author(s):  
Sonja Apostolska ◽  
Marina Eftimoska ◽  
Vasilka Rendzova ◽  
Saso Elencevski ◽  
Nadica Janeva ◽  
...  
Keyword(s):  
Calcium Silicate ◽  
Case Reports ◽  
Setting Time ◽  
Case Series ◽  
Chemical Properties ◽  
High Mechanical Strength ◽  
Handling Characteristics ◽  
Treat Ment ◽  
Wide Range ◽  
Calcium Silicate Cements

Introduction. So far, the most promising and most commonly used materials in endodontic treatment and retreatment were calcium silicate cements. However, due to the shortage of this material and treatment failures, a new bioactive material was introduced - Biodentinetm. It is a calcium silicate based technology, with excellent handling characteristics and biocompatibility. It can be used in various indications, including dentine substitution and endodontic therapy. Case reports. The clinical cases demonstrated excellent healing potential after the treat?ment with Biodentinetm. Conclusion. The bio-silicate technology is highly promising, mostly due to its chemical properties and easy clinical manipulation. The short setting time and high mechanical strength makes Biodentinetm a material easy to han?dle, highly biocompatible, with a wide range of indications.

scholarly journals Physico-Chemical Investigation of Endodontic Sealers Exposed to Simulated Intracanal Heat Application: Hydraulic Calcium Silicate-Based Sealers

Materials ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 728
Author(s):  
David Donnermeyer ◽  
Magdalena Ibing ◽  
Sebastian Bürklein ◽  
Iris Weber ◽  
Maximilian P. Reitze ◽  
...  
Keyword(s):  
Heat Treatment ◽  
Thermal Treatment ◽  
Film Thickness ◽  
Physical Properties ◽  
Calcium Silicate ◽  
Setting Time ◽  
Chemical Properties ◽  
Chemical Changes ◽  
Time Flow ◽  
Heat Application

The aim of this study was to gain information about the effect of thermal treatment of calcium silicate-based sealers. BioRoot RCS (BR), Total Fill BC Sealer (TFBC), and Total Fill BC Sealer HiFlow (TFHF) were exposed to thermal treatment at 37 °C, 47 °C, 57 °C, 67 °C, 77 °C, 87 °C and 97 °C for 30 s. Heat treatment at 97 °C was performed for 60 and 180 s to simulate inappropriate application of warm obturation techniques. Thereafter, specimens were cooled to 37 °C and physical properties (setting time/flow/film thickness according to ISO 6876) were evaluated. Chemical properties (Fourier-transform infrared spectroscopy) were assessed after incubation of the specimens in an incubator at 37 °C and 100% humidity for 8 weeks. Statistical analysis of physical properties was performed using the Kruskal-Wallis-Test (P = 0.05). The setting time, flow, and film thickness of TFBC and TFHF were not relevantly influenced by thermal treatment. Setting time of BR decreased slightly when temperature of heat application increased from 37 °C to 77 °C (P < 0.05). Further heat treatment of BR above 77 °C led to an immediate setting. FT-IR spectroscopy did not reveal any chemical changes for either sealers. Thermal treatment did not lead to any substantial chemical changes at all temperature levels, while physical properties of BR were compromised by heating. TFBC and TFHF can be considered suitable for warm obturation techniques.

Comparative Assessment of Effectiveness of Calcium Silicate Dispersions Produced Using Sucrose and Lactose as Components of Composite Cement Binder

2021 ◽  
Vol 1017 ◽  
pp. 11-20
Author(s):  
Evgeny A. Shoshin ◽  
Valeria V. Strokova ◽  
Zheng Mao Ye
Keyword(s):  
Specific Surface ◽  
Surface Area ◽  
Specific Surface Area ◽  
Calcium Silicate ◽  
Setting Time ◽  
Inhibitory Effect ◽  
Main Element ◽  
Residual Content ◽  
Nucleation Effect ◽  
Wide Range

Silicate micro- and nano-additives are multifunctional in relation to cement systems. Their application can solve a wide range of technological problems while maintaining the economic efficiency of technical solutions. The effect of silicate additives and fillers is determined by their level of dispersion, due to which the technologies for producing nano- and submicro-sized dispersed materials are being developed. The combination of mechanochemical synthesis of modified calcium hydrosilicates with subsequent thermolysis makes it possible to produce calcium silicate dispersions (SCD), which differ in polymodality of the fractional composition including submicro (10–7–10–6 m) and microdimensional (≥10–6 m) modes. The main element of the technology is the use of modifying carbohydrate, which acts as a stabilizer of hydrated phases of silicates. A comparative study of SCD produced using sucrose (sSCD) and lactose (lSCD) revealed the effect of these carbohydrates on the properties of sSCD and lSCD, as well as their effectiveness as a component of cementitious composite binder. It was found that the level of adsorption of modifying carbohydrate determines the physical properties of SCD (granulometry, specific surface area). The relatively high residual content of free sucrose (0.24%) in the composition of sSCD prevents the consolidation of silicates nanoparticles formed during the thermolysis, causes a high content of submicro sized fractions and a high specific surface area with sSCD (26.3 ± 0.7 m2/g). Lactose is absorbed by the silicate phase; the residual content of free lactose does not exceed 0.028% of lSCD. The low content of stabilizing carbohydrate contributes to the development of nanoparticle consolidation, a decrease in the specific surface area of lSCD to 13.0 ± 0.2 m2/g and content of submicrosized fractions. The residual content of free carbohydrates and particle size characteristics of sSCD and lSCD determine the nature of their influence on Cement-SCD-based concrete setting and hardening. The presence of residual sucrose in the composition of sSCD and fine fractions determines the competitive nature of the processes of retardation of hardening and acceleration of hardening of the cement system due to the nucleation effect, as a result of which the curve of the setting time is extreme. In addition, the inhibitory effect of sucrose reduces the strength of concrete on the 7th day. By the 28th day, the inhibitory effect of sucrose has been overcome, and concrete samples demonstrate an 18% increase in compressive strength with a sSCD content of 30%. The low content of residual free lactose in the composition of lSCD causes the nucleation effect. As a result, there is a monotonous reduction in the setting time of concrete mix with an increase in the content of lSCD in the composition of HF, as well as a significant increase in concrete strength (up to 127%) on the 7th day. At the same time, on the 28th day the strength of concrete increases slightly

scholarly journals A comprehensive review on clinical and mechanistic pathophysiological aspects of COVID-19 Malady: How far have we come?

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Baila Shakaib ◽  
Tanzeel Zohra ◽  
Aamer Ikram ◽  
Muhammad Bin Shakaib ◽  
Amna Ali ◽  
...  
Keyword(s):  
Case Reports ◽  
Case Series ◽  
Signs And Symptoms ◽  
Organ Damage ◽  
Underlying Disease ◽  
The Body ◽  
Host Cells ◽  
Irreversible Damage ◽  
Organ Systems ◽  
Wide Range

AbstractSince its outbreak in 2019, the coronavirus disease (COVID-19) has become a pandemic, affecting more than 52 million people and causing more than 1 million mortalities globally till date. Current research reveals a wide array of disease manifestations and behaviors encompassing multiple organ systems in body and immense systemic inflammation, which have been summarized in this review. Data from a number of scientific reviews, research articles, case series, observational studies, and case reports were retrieved by utilizing online search engines such as Cochrane, PubMed, and Scopus from December 2019 to November 2020. The data for prevalence of signs and symptoms, underlying disease mechanisms and comorbidities were analyzed using SPSS version 25. This review will discuss a wide range of COVID-19 clinical presentations recorded till date, and the current understanding of both the underlying general as well as system specific pathophysiologic, and pathogenetic pathways. These include direct viral penetration into host cells through ACE2 receptors, induction of inflammosomes and immune response through viral proteins, and the initiation of system-wide inflammation and cytokine production. Moreover, peripheral organ damage and underlying comorbid diseases which can lead to short term and long term, reversible and irreversible damage to the body have also been studied. We concluded that underlying comorbidities and their pathological effects on the body contributed immensely and determine the resultant disease severity and mortality of the patients. Presently there is no drug approved for treatment of COVID-19, however multiple vaccines are now in use and research for more is underway.

Temporal Bone Fractures Caused by Ballistic Projectiles: A Systematic Review

2020 ◽  
pp. 019459982096879
Author(s):  
Kenneth L. Kennedy ◽  
Elizabeth Cash ◽  
Jessica Petrey ◽  
Jerry W. Lin
Keyword(s):  
Temporal Bone ◽  
Bone Fractures ◽  
Case Reports ◽  
Case Series ◽  
Gunshot Wounds ◽  
Individual Case ◽  
Future Research ◽  
Wide Range ◽  
Intracranial Complications

Objective Ballistic injuries to the temporal bone are uncommon but devastating injuries that damage critical neurovascular structures. This review describes outcomes after ballistic injuries to the temporal bone and offers initiatives for standardized high-quality future research. Data Sources A systematic search of PubMed, Embase, and Cochrane. Review Methods Studies in the review included adults who experienced temporal bone fractures due to gunshot wounds and survived longer than 48 hours. Individual case reports were excluded. The various searches returned 139 results, of which 6 met inclusion criteria. Results Most of the included studies are case series with low-level evidence that report a wide range of outcomes and follow-up. Outcomes include demographic patient information, audiologic outcomes, vascular injuries, intracranial complications, facial nerve function, and surgical indications. Conclusion This review is the first to characterize the nature and progression of patients who experienced gunshot wounds to the temporal bone. Although all patients share an etiology of injury, they often have vastly different hospital courses and outcomes. This review provides a basis for future studies to guide care for these injuries, as most of the existing literature includes small dated case series.

scholarly journals Effect of Silver Nanoparticles on Physicochemical and Antibacterial Properties of Calcium Silicate Cements

2016 ◽  
Vol 27 (5) ◽  
pp. 508-514 ◽  
Author(s):  
Fernando Vazquez-Garcia ◽  
◽  
Mário Tanomaru-Filho ◽  
Gisselle Moraima Chávez-Andrade ◽  
Roberta Bosso-Martelo ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Silver Nanoparticles ◽  
Compressive Strength ◽  
Antibacterial Activity ◽  
Calcium Silicate ◽  
Setting Time ◽  
Antibacterial Properties ◽  
Mineral Trioxide Aggregate ◽  
Biological Properties ◽  
Calcium Silicate Cements

Abstract Mineral trioxide aggregate (MTA) and Portland cement (PC) are calcium silicate cements. They have similar physicochemical, mechanical and biological properties. The addition of zirconium oxide (ZrO2) to PC provides radiopacity. Silver nanoparticles (AgNPs) may improve some properties of cements. The aim of this study was to evaluate the effect of AgNPs on physicochemical/mechanical properties and antibacterial activity of white MTA (WMTA) and PC associated with ZrO2. The following materials were evaluated: WMTA; PC 70% + ZrO2 30%; WMTA+ AgNPs; and PC 70% + ZrO2 30% + AgNPs. The study evaluated radiopacity, setting time, pH, compressive strength and solubility. For radiopacity analysis, radiographs were made alongside an aluminum (Al) step wedge. To evaluate the antibacterial activity, direct contact test was performed on planktonic cells and Enterococcus faecalis biofilm induced on bovine root dentin for 14 days. The experimental periods were 5 and 15 h. Data were obtained as CFU mL-1. The obtained data were submitted to ANOVA and Tukey tests (p<0.05). The addition of AgNPs to WMTA increased the pH, lowered the solubility and the initial and final setting times. The addition of AgNPs to PC/ZrO2 maintained the pH, lowered the solubility, and increased the setting time and compressive strength. The radiopacity of all materials was higher than 4 mmAl. The addition of AgNPs promoted an increase in antibacterial activity for calcium silicate cements and favored the physicochemical and mechanical properties of the materials.

scholarly journals Examination of Calcium Silicate Cements with Low-Viscosity Methyl Cellulose or Hydroxypropyl Cellulose Additive

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Toshiaki Baba ◽  
Yasuhisa Tsujimoto
Keyword(s):  
Calcium Ion ◽  
Calcium Silicate ◽  
Zirconium Oxide ◽  
Setting Time ◽  
Mineral Trioxide Aggregate ◽  
Methyl Cellulose ◽  
Hydroxypropyl Cellulose ◽  
Ion Release ◽  
Low Viscosity ◽  
Calcium Silicate Cements

The purpose of this study was to improve the operability of calcium silicate cements (CSCs) such as mineral trioxide aggregate (MTA) cement. The flow, working time, and setting time of CSCs with different compositions containing low-viscosity methyl cellulose (MC) or hydroxypropyl cellulose (HPC) additive were examined according to ISO 6876-2012; calcium ion release analysis was also conducted. MTA and low-heat Portland cement (LPC) including 20% fine particle zirconium oxide (ZO group), LPC including zirconium oxide and 2 wt% low-viscosity MC (MC group), and HPC (HPC group) were tested. MC and HPC groups exhibited significantly higher flow values and setting times than other groups (p<0.05). Additionally, flow values of these groups were higher than the ISO 6876-2012 reference values; furthermore, working times were over 10 min. Calcium ion release was retarded with ZO, MC, and HPC groups compared with MTA. The concentration of calcium ions was decreased by the addition of the MC or HPC group compared with the ZO group. When low-viscosity MC or HPC was added, the composition of CSCs changed, thus fulfilling the requirements for use as root canal sealer. Calcium ion release by CSCs was affected by changing the CSC composition via the addition of MC or HPC.

scholarly journals Development of resin-based bioactive endodontic cements with glycerol salicylate and calcium silicate

2020 ◽  
Vol 61 (1) ◽  
pp. 69-76
Author(s):  
Rafaela Cassaro Pistorello ◽  
Gabriela De Souza Balbinot ◽  
Vicente Castelo Branco Leitune ◽  
Fabricio Mezzomo Collares
Keyword(s):  
Calcium Silicate ◽  
Methyl Salicylate ◽  
Setting Time ◽  
Sol Gel ◽  
Chemical Properties ◽  
Distilled Water ◽  
Physical Chemical ◽  
Time Flow

Introduction: The combination of sol-gel derived calcium silicate particles and glycerol salicylate resins may enhance the pyhisico-chemical properties contribute to the understanding of the interaction between these materials. This study aims to evaluate the physical-chemical properties of resin-based bioactive endodontic cements with glycerol salicylate resins and calcium silicate particles. Materials and methods: Calcium silicate was produced by the sol-gel route, while the resin was produced by mixing 60wt% glycerol salicylate, 30wt% methyl salicylate and 10wt% distilled water. Calcium silicate was added in three different concentrations, 50, 40 and 25% by weight. The cement was tested for setting time, flow, radiopacity and pH. Results: The 50:50 group shows the time of 15min8s while the 75:25 shows the time of 256min13s (p

Setting time and expansion in different soaking media of experimental accelerated calcium-silicate cements and ProRoot MTA

2009 ◽  
Vol 108 (6) ◽  
pp. e39-e45 ◽  
Author(s):  
Maria Giovanna Gandolfi ◽  
Francesco Iacono ◽  
Kelli Agee ◽  
Francesco Siboni ◽  
Franklin Tay ◽  
...  
Keyword(s):  
Calcium Silicate ◽  
Setting Time ◽  
Calcium Silicate Cements

scholarly journals A Systematic Review of the Cardiovascular Manifestations and Outcomes in the Setting of Coronavirus-19 Disease

2020 ◽  
Author(s):  
Samarthkumar Thakkar ◽  
Shilpkumar Arora ◽  
Ashish Kumar ◽  
Rahul Jaswaney ◽  
Mohammed Faisaluddin ◽  
...  
Keyword(s):  
Systematic Review ◽  
Case Reports ◽  
Case Series ◽  
Inclusion Criteria ◽  
Mortality And Morbidity ◽  
Future Studies ◽  
Treatment And Prevention ◽  
Wide Range ◽  
Myocardial Infection ◽  
The Impact

The impact of coronavirus disease, 2019 (COVID-19), has been profound. Though COVID-19 primarily affects the respiratory system, it has also been associated with a wide range of cardiovascular (CV) manifestations portending extremely poor prognosis. The principal hypothesis for CV involvement is through direct myocardial infection and systemic inflammation. We conducted a systematic review of the current literature to provide a foundation for understanding the CV manifestations and outcomes of COVID-19. PubMed and EMBASE databases were electronically searched from the inception of the databases through April 27th, 2020. A second literature review was conducted to include major trials and guidelines that were published after the initial search but before submission. The inclusion criteria for studies to be eligible were case reports, case series, and observation studies reporting CV outcomes among patients with COVID-19 infection. This review of the current COVID-19 disease and CV outcomes literature revealed a myriad of CV manifestations with potential avenues for treatment and prevention. Future studies are required to understand on a more mechanistic level the effect of COVID-19 on the myocardium and thus provide avenues to improve mortality and morbidity.

Interactions Between Warfarin and Three Commonly Prescribed Fluoroquinolones

2008 ◽  
Vol 42 (5) ◽  
pp. 680-685 ◽  
Author(s):  
Douglas N Carroll ◽  
Dana G Carroll
Keyword(s):  
Case Reports ◽  
Data Extraction ◽  
Case Series ◽  
International Normalized Ratio ◽  
Bleeding Complications ◽  
Published Data ◽  
Wide Range ◽  
Retrospective Cohort Studies ◽  
Typical Treatment ◽  
Review Reports

Objective: To critically evaluate a possible increased anticoagulant response during concomitant warfarin and fluoroquinolone therapy. Data Sources: A literature search was conducted using PubMed, International Pharmaceutical Abstracts, and MEDLINE, from inception to January 2008, combining the term warfarin individually with ciprofloxacin, levofloxacin, and moxifloxacin. These 3 quinolones were selected based on their commercial availability and use in the US. Study Selection and Data Extraction: All publication types including human participants and published in English were eligible for review. Reports were selected based on the use of typical treatment courses of fluoroquinolones during concomitant warfarin therapy and the reporting of prothrombin time (PT) or international normalized ratio (INR). Data Synthesis: Twenty-two publications were evaluated including 16 case reports or case series, 2 retrospective cohort studies, and 4 prospective studies, which included 2 placebo-controlled investigations, identified reports covered a wide range of patient ages with multiple comorbidities. Changes in PT and INR values were considerably variable and inconsistent during concomitant warfarin and fluoroquinolone therapy. Results from the 6 structured reports demonstrated mean increases in PT and INR values that were clinically insignificant. However, some patients experienced significant increases above the desired therapeutic range. Increased anticoagulation was typically observed within the first week of concomitant fluoroquinolone therapy. Bleeding complications during times of increased anticoagulation were not always observed, but did result in death for 2 patients. Conclusions: Published data show no consistent increase in anticoagulant effects during concomitant warfarin and 3 commonly prescribed fluoroquinolones. Therefore, more frequent monitoring during concomitant therapy would be prudent.

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