scholarly journals Surgical treatment of invasive vulvar cancer

2012 ◽  
Vol 65 (3-4) ◽  
pp. 97-101 ◽  
Author(s):  
Milos Pantelic ◽  
Srdjan Djurdjevic ◽  
Dragan Nikolic ◽  
Marko Maksimovic
Keyword(s):  
Surgical Treatment ◽  
Lymph Nodes ◽  
Muscle Flap ◽  
Wound Dehiscence ◽  
Regional Lymph Nodes ◽  
Gynecology And Obstetrics ◽  
Healthy Area ◽  
General Physical ◽  
Local Regional Recurrence ◽  
Novi Sad

This paper presents the surgical treatment of invasive cancer of the vulva at the Department of Gynecology and Obstetrics in Novi Sad in the period from 2000 to 2010. Forty-one patients underwent different surgical procedures depending on their stage of the disease, age and general physical condition assessed according to the International Federation of Gynecologists and Obstetricians: wide excision to the healthy area with negative edges of 10 mm, simplex - radical vulvectomy or hemivulvectomy, block dissection of the vulva by Way, one-sided or bilateral lymphadenectomy and skin-muscle flap to cover the resulting skin defects. The number of removed lymph nodes on one side ranged from 8 to 19, the average being 12.6. Various postoperative complications (inflammation and wound dehiscence, lymphorrhoea, lymphocyst and limb lymphedema) developed in 9 (21.9%) and the local regional recurrence was recorded in 7 (17%) patients. The outcome was lethal in 4 (9.8%) surgically treated women. The primary surgical procedure is always individually planned and the choice of individual plans depends on three main factors: the size and position of the primary tumor in relation to the center line of the vulva (clitoral area - anus) and the involvement of regional lymph nodes. In order to reduce the psychosexual morbidity the preference is nowadays widely given to the local excision with adequate and histopathologically confirmed negative edges of the tumor together with determining the presence of metastases in sentinel lymph nodes.

scholarly journals Block dissection of inguinofemoral lymph nodes using separate "S" incision in surgical treatment of vulvar carcinoma

2004 ◽  
Vol 57 (7-8) ◽  
pp. 343-348
Author(s):  
Srdjan Djurdjevic ◽  
Dimitrije Segedi
Keyword(s):  
Surgical Treatment ◽  
Postoperative Complications ◽  
Postoperative Period ◽  
Malignant Tumors ◽  
Wound Dehiscence ◽  
Obstetrics And Gynecology ◽  
Vulvar Carcinoma ◽  
Novi Sad ◽  
Inguinofemoral Lymphadenectomy ◽  
Female Genital

Vulvar carcinomas account for almost 3-5% of all malignant tumors of the female genital organs. The primary therapeutic approach is surgical in all cases. Since 1994, we have used a separate "S" incision for inguinofemoral lymphadenectomy in the treatment of invasive vulvar carcinoma. In the period from 1985 to 2003, 46 patients with invasive forms of vulvar carcinoma were operated at the Department of Obstetrics and Gynecology in Novi Sad. Inguinofemoral lymphadenectomy was performed in 37 (84.4%) patients. During 1994, a wide "block" dissection of the vulva, mons pubis and inguinal area of a "butterfly" shape was performed, whereas during the following period, the operative area was reduced by application of separate inguinal "S" incisions leaving a tissue bridge in between. There were 5 patients with stage I, 1 with stage II and 4 with stage III carcinoma. By applying the technique of two separate inguinal "S" incisions we achieved shortening the intrahospital postoperative period to 14 days and reduction of the risk of wound dehiscence and postoperative complications in the period following 1994.

scholarly journals Radical hysterectomy in surgical treatment of invasive cervical cancer at the Department of gynecology and obstetrics in Novi Sad in the period 1993-2013.

2015 ◽  
Vol 68 (7-8) ◽  
pp. 227-233
Author(s):  
Srdjan Djurdjevic ◽  
Sanja Stojanovic ◽  
Milos Pantelic ◽  
Dragan Nikolic ◽  
Marijana Basta-Nikolic ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Lymph Nodes ◽  
Radical Hysterectomy ◽  
Invasive Cervical Cancer ◽  
International Federation ◽  
Stage I ◽  
Stage Ii ◽  
Gynecology And Obstetrics ◽  
Paraaortic Lymph Nodes ◽  
Novi Sad

Introduction. During the period from 1993 - 2013, 175 women with invasive cervical cancer underwent radical hysterectomy sec. Wertheim-Meigs at the Department of Gynecology and Obstetrics, Clinical Center of Vojvodina in Novi Sad. Indications for radical hysterectomy comprise histopathologically confirmed invasive cervical cancer in stages I B 1 - II B according to the International Federation of Gynecology and Obstetrics. Material and Methods. Stage of the disease or extent of the disease spread to the adjacent structures was assessed in accordance with the International Federation of Gynecology and Obstetrics staging system from 2009. Exclusion criteria were all other stages of this disease: I A and stages higher than II B, as well as the absence of definite histological confirmation of the cervical cancer (primary endometrial or vaginal cancer which infiltrates the uterine cervix). Prior the operation, the following had to be done: the imaging of pelvis and abdomen, chest X-ray in two directions, electrocardiography, internist and anesthesiological examination. Results. The patients? age ranged from 24-79 years (x : 46 years), and the operation duration was 120-300 minutes (x : 210 min.). Stage I B 1 was found in 64.6% of operated patients, 14.8% of the patients were in stage I B 2, 9.1% were in stage II A and 11.4 % were in stage II B. Blood loss during the operation ranged from 50-800 ml (on average 300 ml), and the number of removed lymph nodes per operation was 14-75 (x : 32). Intraoperative and postoperative complications developed in 6.8% of and 17.7% of patients, respectively. Recurrence was reported in 22 (12.5%) patients, most often in paraaortic lymph nodes (3.4%) and parametria (2.8%), while the overall 5-year survival rate was 87% until 2008. Concluision. Wertheim-Meigs radical hysterectomy is a basic surgical technique for the treatment of initial stages of invasive cervical cancer.

scholarly journals A lesion of contralateral neck lymph nodes in oral tongue cancer with clinically negative neck lymph nodes (clinical case)

2019 ◽  
Vol 9 (3) ◽  
pp. 83-88 ◽  
Author(s):  
Z. A.‑G. Radzhabova ◽  
M. A. Kotov ◽  
S. N. Novikov ◽  
P. I. Krzhivizchki ◽  
O. I. Ponomareva ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Lymph Nodes ◽  
Primary Tumor ◽  
Clinical Case ◽  
Clinical Laboratory ◽  
Tongue Cancer ◽  
Combined Treatment ◽  
Regional Lymph Nodes ◽  
Free Part ◽  
Neck Lymph Nodes

The objective is to present a clinical case of combined treatment of cancer of the tongue and its progression to the contralateral lymph nodes of the neck using data on individual lymphatic outflow from the primary tumor of the tongue.Clinical case. Clinical, laboratory, radiological and pathomorphological data of a 50-year-old patient with a diagnosis of squamous human papillomavirus-negative cancer of the free part of the tongue and clinically negative lymph nodes of the neck with cT2N0M0. The patient underwent radical surgical treatment in the amount of hemiglossectomy and ipsilateral selective cervical lymphadenectomy after two courses of polychemotherapy according to the cisplatin + 5-fluorocracil regimen with partial regression and adjuvant treatment in the amount of conformal remote radiation therapy combined with chemotherapy. 9 months after the end of treatment, progression to the lymph nodes of the neck of the contralateral side was revealed, which accumulated a radiopharmaceutical before treatment.Conclusion. The described clinical case shows the importance of studying the lymphatic outflow from the primary tumor of the tongue to the regional lymph nodes in order to plan surgical treatment on the regional lymphatic collector in patients with squamous cell carcinoma of the free part of the tongue.

Salivary duct adenocarcinoma: a high grade malignancy

1986 ◽  
Vol 100 (1) ◽  
pp. 105-114 ◽  
Author(s):  
Kathleen K. Hui ◽  
John G. Batsakis ◽  
Mario A. Luna ◽  
Bruce MacKay ◽  
Robert M. Byers
Keyword(s):  
Surgical Treatment ◽  
Lymph Nodes ◽  
Local Control ◽  
Clinical Course ◽  
High Grade ◽  
Salivary Duct ◽  
Regional Lymph Nodes ◽  
Grade Malignancy ◽  
Distinguishing Features ◽  
High Grade Malignancy

AbstractSalivary duct carcinomas of the major salivary glands have two major distinguishing features. They closely resemble ductal carcinomas of the breast and they are high-grade malignancies. In general, but particularly for carcinomas measuring three or more centimeters in size, the clinical course is one characterized by a resistance to local control, metastases to regional lymph nodes and distant sites, and death within a few years after primary surgical treatment.

A case of primary biliary cirrhosis with sarcoid reaction in the regional lymph nodes after surgery of early gastric cancer

Kanzo ◽  
2005 ◽  
Vol 46 (7) ◽  
pp. 437-442 ◽  
Author(s):  
Tadashi YOSHIDA ◽  
Atsushi NAGASAKA ◽  
Yayoi OGAWA ◽  
Syuji NISHIKAWA ◽  
Akifumi HIGUCHI
Keyword(s):  
Gastric Cancer ◽  
Early Gastric Cancer ◽  
Primary Biliary Cirrhosis ◽  
Lymph Nodes ◽  
Biliary Cirrhosis ◽  
Regional Lymph Nodes ◽  
Sarcoid Reaction
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