scholarly journals Significance of systemic lymphadenectomy in regard to the extent of metastatic lymph node involvement in patients operated for gastric carcinoma

2003 ◽  
Vol 56 (9-10) ◽  
pp. 451-456
Author(s):  
Dejan Stevanovic ◽  
Dragan Radovanovic ◽  
Ivan Pavlovic ◽  
Nebojsa Mitrovic ◽  
Milena Vukovic ◽  
...  
Keyword(s):  
Lymph Node ◽  
Gastric Carcinoma ◽  
Lymph Nodes ◽  
Metastatic Lymph Node ◽  
Lymph Node Involvement ◽  
Metastatic Lymph Nodes ◽  
Stage Of Disease ◽  
Systematic Lymphadenectomy ◽  
Metastatic Lymph ◽  
Node Involvement

Introduction Formation of lymphatic metastasis is an important prognostic factor in treatment of gastric carcinoma. In this paper we would like to point to the importance of systematic lymphadenectomy in regard to extent of metastatic lymph node involvement in patients with gastric carcinoma. Material and methods This investigation included 114 patients with diagnosis of gastric carcinoma undergoing systematic lymphadenectomy. We analyzed metastatic lymph node involvement considering: 1. tumor localization; 2. histopathologic type; 3. depth of tumor invasion; 4. extent of lymph node resection; 5. stage of disease. Results In the course of this study, 2100 lymph nodes were extracted by systematic lymphadenectomy (18.42 lymph nodes per patient on average). Out of this number, about 27% of lymph nodes were involved with metastasis, and 60% of positive lymph nodes belonged to the first, 25.7% to the second, 10.2% to the third and 3.8% to the fourth drainaged group. The most frequent localization (over 56%) of tumors was the distal third region of stomach. Histopathologically, most common type of carcinoma was intestinal carcinoma, with metastasis in first and second drainage group. A great number of patients have tumors with infiltration of the serosa. Those patients had metastases in lymph nodes in over 42%. Most patients (58%) belonged to IV stage of disease and presented with highest number of involved metastatic lymph nodes in all drainage groups. Discussion In our patients high metastatic involvement of all four drainage groups of lymph nodes was established. Up to date standard lymphadenectomy (D1) which has been performed increased the length of survival of these patients. Conclusion By systematic lymphadenectomy we removed a great number of metastatic lymph nodes with beneficial effect on survival of patients with gastric carcinoma.

Is Metastatic Lymph Node Ratio Superior to the Number of Metastatic Lymph Nodes to Assess Outcome and Survival of Gastric Cancer?

2010 ◽  
Vol 33 (3) ◽  
pp. 101-105 ◽  
Author(s):  
Ahmet Bilici ◽  
Bala B.O. Ustaalioglu ◽  
Mahmut Gumus ◽  
Mesut Seker ◽  
Burcak Yilmaz ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Lymph Node Ratio ◽  
Metastatic Lymph Node ◽  
Metastatic Lymph Nodes ◽  
Metastatic Lymph ◽  
Node Ratio

scholarly journals Computed tomography–based distribution of involved lymph nodes in patients with upper esophageal cancer

2015 ◽  
Vol 22 (3) ◽  
pp. 178 ◽  
Author(s):  
M. Li ◽  
Y. Liu ◽  
L. Xu ◽  
Y. Huang ◽  
W. Li ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Regional Lymph Node ◽  
Metastatic Lymph Node ◽  
Radiation Therapy Oncology Group ◽  
Lymph Node Involvement ◽  
Specific Distribution ◽  
Node Involvement ◽  
Upper Thoracic

BackgroundDelineating the nodal clinical target volume (ctvn) remains a challenging task in patients with cervical or upper thoracic esophageal carcinoma (ec). In particular, the extent of the lymph area that should be included in the irradiation field remains controversial. In the present study, the extent of the ctvn was determined based on the incidence of lymph node involvement mapped by computed tomography (ct) imaging.Methods Our study included 468 patients who were diagnosed with cervical and upper thoracic ec and who received staging information between June 2005 and April 2011. The anatomic distribution of metastatic regional lymph nodes was mapped using ct images and grouped using the levels established by the Radiation Therapy Oncology Group. The probability of the various groups being involved was examined. If a lymph node group had a probability of 10% or more of being involved, it was considered at high risk for metastasis, and elective treatment as part of the ctvn was recommended.Results Lymph node involvement was mapped by ct in 256 patients (54.7%). Not all lymph node groups should be included in the ctvn. For cervical lesions, the involved lymph nodes were located mainly between the hyoid bone and the arcus aortae; the recommended ctvn should consist of the neck lymph nodes at levels iii and iv (supraclavicular group) and thoracic groups 2 and 3P. In upper thoracic ec patients, most of the involved lymph nodes were distributed between the cricoid cartilage and the subcarinal area; the ctvn should cover the supraclavicular group and thoracic nodal groups 2, 3P, 4, 5, and 7.Conclusions Our ct-based study indicates a specific distribution and incidence of metastatic lymph node groups in patients with cervical and upper thoracic ec. The results suggest that regional lymph node groups should be electively included in the ctvn for precise radiation administration.

scholarly journals Effects of systematic lymphadenectomy on length of survival in patients with gastric carcinoma

2004 ◽  
Vol 57 (3-4) ◽  
pp. 175-180 ◽  
Author(s):  
Dejan Stevanovic ◽  
Dragan Radovanovic ◽  
Ivan Pavlovic ◽  
Petar Kostic
Keyword(s):  
Gastric Cancer ◽  
Survival Rate ◽  
Gastric Carcinoma ◽  
Lymph Nodes ◽  
Advanced Gastric Cancer ◽  
Tumor Recurrence ◽  
Metastatic Lymph Nodes ◽  
Systematic Lymphadenectomy ◽  
Metastatic Lymph ◽  
Gastric Cancer Patients

Introduction In the last few years there have been arguments between the Japanese and West European surgeons about benefits of systematic lymphadenectomies in surgery of gastric cancer. In this paper we would like to point out effects of systematic lymphadenectomies on survival of patients with gastric carcinoma. Material and methods This investigestion included two groups of patients. The first group of 126 patients with gastric carcinoma underwent peritumor lymphadenectomy Dl. The second group of 114 patients with gastric carcinoma underwent more radical types of lympadenectomy (D2, D2%, D3). Survival analysis included investigation of the following:1 depth of tumor invasion, 2. metastatic involvement of the lymph nodes 3. tumor stage, 4. tumor recurrence. Results Most of examined patients presented with invasion and serosal and subserosal penetration (about 75% in both groups). More than 42% of lymph nodes had metastases and patients with systematic lymphadenctomy had better survival. Patients without subserosal invasion did not have metastatic lymph nodes in H, III, IV drianaged groups. There was no difference in regard to length of survival between the two analyzed group. 5-year survival rate "was highest in stage I of gastric carcinoma (86%), but in stage IV 5-year survival rate was only 3.8%. Local recurrence (26%) and lymph node metastases (53%) were common causes of tumor recurrence in group with peritumor lymphadenectomy. In all groups of patients with advanced gastric cancer patients undergoing systematic lymphadenectomy presented with higher survival rate. Discussion Patients with advanced gastric cancer presented with higher number of metastatic lymph nodes in III and IV drainaged groups. In this stage systematic lympadenectomy played the main role. In the group of early gastric cancer there were no patients with metastatic lymph nodes in drainaged groups. Conclusion D2 lympahedenectomy is a standard procedure for a great number of patients with gastric carcinoma, with high survival rate. Only in the group of advanced gastric cancer, patients un?dergoing more radical types of lymphadenectomies (D2%, D3) presented with better survival rates.

Axillary ultrasound scans in detecting metastatic lymph node involvement in breast cancer patients

2015 ◽  
Vol 70 ◽  
pp. S1
Author(s):  
Tin A. Sein ◽  
Vandana Gaur ◽  
Makam Kishore ◽  
Ramchandra Rattehalli ◽  
Ramlal Nangalia
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Cancer Patients ◽  
Metastatic Lymph Node ◽  
Lymph Node Involvement ◽  
Breast Cancer Patients ◽  
Axillary Ultrasound ◽  
Metastatic Lymph ◽  
Node Involvement
Sign in / Sign up

Export Citation Format

Share Document