scholarly journals A study of the electrochemical behavior of methomyl on a gold electrode in a neutral electrolyte

2009 ◽  
Vol 74 (5) ◽  
pp. 573-579 ◽  
Author(s):  
Andjelka Tomasevic ◽  
Milka Avramov-Ivic ◽  
Slobodan Petrovic ◽  
Mica Jovanovic ◽  
Dusan Mijin
Keyword(s):  
Gold Electrode ◽  
Hplc Analysis ◽  
Linear Sweep Voltammetry ◽  
Electrochemical Determination ◽  
The Other ◽  
Potential Range ◽  
Linear Sweep ◽  
Qualitative And Quantitative ◽  
Neutral Electrolyte

A gold electrode was used for the qualitative and quantitative electrochemical determination of analytical methomyl in a neutral electrolyte (0.050 M NaHCO3) using cyclic linear sweep voltammetry. In the potential range from -800 mV vs. SCE to 1000 mV vs. SCE the analytical methomyl was quantitatively determined in the concentration range 4.0-16 mg L-1. In the potential range from -1300 mV vs. SCE to 1300 mV vs. SCE, methomyl was qualitatively determined by two anodic and four cathodic reactions. Cycling the potential in this range for 150 min caused the degradation of the molecule, which was confirmed by HPLC analysis. On the other hand, technical methomyl exhibited an inhibition of the gold electrode surface due to the impurities.

scholarly journals A study of the electrochemical activity of some macrolide antibiotics on a gold electrode in a neutral electrolyte

2007 ◽  
Vol 72 (12) ◽  
pp. 1427-1436 ◽  
Author(s):  
Milka Avramov-Ivic ◽  
Slobodan Petrovic ◽  
D.Z. Mijin
Keyword(s):  
Gold Electrode ◽  
Structural Changes ◽  
Linear Sweep Voltammetry ◽  
Electrochemical Determination ◽  
Electrochemical Reactions ◽  
Cathodic Peak ◽  
Experimental Conditions ◽  
Neutral Electrolyte ◽  
Anodic Reactions

The aim of the present study is to present the different reactivity of azithromycin and clarithromycin (pure and commercial) at a gold electrode in neutral electrolyte using cyclic linear sweep voltammetry under the same experimental conditions. A gold electrode was successfully used for the electrochemical qualitative and quantitative determination of azithromycin dihydrate and azithromycin from capsules (Hemomycin?) and for the separation of azithromycin from one of the excipients, lactose monohydrate. The good catalytically activity of the gold electrode was employed only for the qualitative electrochemical determination of pure clarithromycin by appearance of one cathodic and four anodic reactions, which enabled structural changes in this molecule during electrochemical reactions to be studied. Commercial clarithromycin, Clathrocyn? was qualitative determined by one reproducible anodic reaction. The activity of one of the excipients, Avicel, observed as a cathodic peak at different potential from the cathodic peak obtained with pure clarithromicin was used for the determination of its presence in Clathrocyn? tablets. FTIR Analysis showed the apparent changes in structure of pure clarithromycin, as well as in the molecule of clarithromycin in Clathrocyn? tablets. HPLC Analysis showed a significant decrease in the concentration of azithromycin, Hemomycin? clarithromycin and Clathrocyn? after the electrochemical reactions.

Anodic Voltammetric Behavior of Lincomycin and its Electroanalytical Determination in Pharmaceutical Dosage form and Urine at Gold Electrode

2017 ◽  
Vol 231 (5) ◽  
Author(s):  
Jyothi C. Abbar ◽  
Manjunath D. Meti ◽  
Sharanappa T. Nandibewoor
Keyword(s):  
Gold Electrode ◽  
Dosage Form ◽  
Oxidation Process ◽  
Linear Sweep Voltammetry ◽  
Linear Sweep ◽  
Experimental Conditions ◽  
Pharmaceutical Dosage Form ◽  
Antibiotic Drug ◽  
Voltammetric Behavior

AbstractThe anodic voltammetric behavior of an antibiotic drug, lincomycin hydrochloride (LIN) at gold electrode (GE) has been investigated using cyclic and linear sweep voltammetry. The dependence of the current on pH, concentration and scan rate were investigated to optimize the experimental conditions for the determination of lincomycin. The anodic peak was characterized and the process was adsorption-controlled. The number of electrons transferred in the oxidation process was calculated. In the range of 8.0×10

scholarly journals Electrochemical Determination of Trichloroacetic Acid using Platinum Electrode

2013 ◽  
Vol 9 (2) ◽  
pp. 1933-1942
Author(s):  
M. Khodari ◽  
A. A. Abd-Elrady ◽  
E.M. Rabie ◽  
H.F. Assaf
Keyword(s):  
Trichloroacetic Acid ◽  
Platinum Electrode ◽  
Supporting Electrolyte ◽  
Linear Sweep Voltammetry ◽  
Electrochemical Determination ◽  
Linear Sweep ◽  
Solution Ph ◽  
Optimized Conditions ◽  
Analytical Utility

The electrochemical reduction of Trichloroacetic acid (TCA) on a platinum electrode by cyclic and linear sweep voltammetry was described. The measurements were investigated under optimized conditions. The supporting electrolyte was 0.01 M sodiumnitrate solution (pH 6.0), scan rate 50mV\s and the reached detection and quantification limits was 4x10-6 mol l-1. The obtained result indicated linear increasing of the current with concentration of TCAA between lower and upper detection limits and excellent sensitivity towards TCAA reduction, which demonstrates the analytical utility of platinum electrode. Meanwhile, interference from other ions and substances were examined. The experimental results indicate that the method for the determination of TCAA samples is successful comparing with other methods or techniques.

scholarly journals Electrochemical determination of sertraline in pharmaceutical formulation and serum using a gold electrode in a pH 8.4 bicarbonate solution

2021 ◽  
Vol 152 (2) ◽  
pp. 185-192
Author(s):  
Jelena Lović ◽  
Jelena Lađarević ◽  
Nemanja Trišović ◽  
Filip Andrić ◽  
Aleksandar Mladenović ◽  
...  
Keyword(s):  
Gold Electrode ◽  
Electrochemical Determination ◽  
Pharmaceutical Formulation

scholarly journals Linear sweep polarographic determination of nucleic acids using acridine orange as a bioprobe

2007 ◽  
Vol 72 (11) ◽  
pp. 1085-1094 ◽  
Author(s):  
Wei Sun ◽  
Na Zhao ◽  
Xianlong Yuan ◽  
Kui Jiao
Keyword(s):  
Aqueous Solution ◽  
Acridine Orange ◽  
Electrochemical Method ◽  
Electrochemical Determination ◽  
Determination Method ◽  
Linear Regression Equation ◽  
Peak Potential ◽  
Linear Sweep ◽  
Buffer Solution

The interaction of acridine orange (AO) with double-stranded (ds) DNA in aqueous solution was investigated by linear sweep polarography (LSP) on a dropping mercury working electrode (DME). In pH 2.5 Britton-Robinson (B-R) buffer solution, AO had a sensitive linear sweep polarographic reductive peak at -0.89 V (vs. SCE), which could be greatly inhibited by the addition of dsDNA, with a positive shift of the peak potential. Based on the decrease of the reductive peak current, a new quantitative electrochemical determination method for dsDNA was developed with a linear range of 2.0?20.0 mg l-1 and the linear regression equation: ?Ip" (nA) = 111.90 C (mg l-1)+125.32 (n = 9, ? = 0.997). The influences of commonly co-existing substances, such as metal ions, amino acid, etc., on the determination were also investigated. The method is sensitive, rapid and simple with good selectivity. The new proposed method was further applied to the detection of RNA and three synthetic samples containing dsDNA with satisfactory results. The binding number and the equilibrium constant between dsDNA and AO were calculated by an electrochemical method.

Determination of Rate and Equilibrium Constants for the Reactions between Electron Transfer Mediators and Proteins by Linear Sweep Voltammetry

1997 ◽  
Vol 249 (2) ◽  
pp. 212-218 ◽  
Author(s):  
Vernon D. Parker ◽  
Alisa Roddick ◽  
Lance C. Seefeldt ◽  
Haijiang Wang ◽  
Gang Zheng
Keyword(s):  
Electron Transfer ◽  
Equilibrium Constants ◽  
Linear Sweep Voltammetry ◽  
Linear Sweep
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