scholarly journals St. John's Wort Hypericum perforatum L.: Supercritical extraction, antimicrobial and antidepressant activity of extract and some component

2006 ◽  
Vol 60 (3-4) ◽  
pp. 61-71 ◽  
Author(s):  
Sandra Glisic ◽  
Sretko Popadic ◽  
Dejan Skala
Keyword(s):  
Essential Oil ◽  
Hypericum Perforatum ◽  
Antidepressant Activity ◽  
Supercritical Extraction ◽  
Bioactive Components ◽  
St John’S Wort ◽  
St John's Wort ◽  
Medicinal Treatment ◽  
Hypericum Perforatum L ◽  
The Many

St. John's Wort, the Hypericum perforatum L. is one of the most analyzed plant species today. Plant was characterized with a wide ecological spectrum and is a plant with beautiful yellow flowers. St. John's Wort was used and still is in used in traditional medicine all over the World. Many bioactive components from St. John's Wort like hypericine, hyperforine, qercetrine and essential oil, were isolated and have been used in medicine. The most popular use of Hipericum extract is as an antidepressant for the medicinal treatment of mild and high depression. The medical use of hyperforine in photodynamic therapy for cancer treatment has now been intensively analyzed. The extract of St. John's Wort showed high antimicrobial, even on pathogenic microorganisms as well as antiviral activity. The use of bioactive components from St. John's Wort depends on the possibility to isolate them in the pure state. It seems that supercritical extraction with carbon dioxide might to be the best solution for obtaining pure extract as well as some of the components present in the essential oil and extract of St. John's Wort. Such a conclusion is supported by the many results of recently performed and published in scientific journals.

Determination of Hypericin in St. John's Wort (Hypericum perforatum L.) extracts using HPLC-ED

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
E Sofic ◽  
A Copra Janicijevic ◽  
M Maksimovic ◽  
I Tahirovic ◽  
L Klepo ◽  
...  
Keyword(s):  
Hypericum Perforatum ◽  
St John’S Wort ◽  
St John's Wort ◽  
Hypericum Perforatum L

Effect of herbicides on St John's wort (Hypericum perforatum L.)

1991 ◽  
Vol 31 (4) ◽  
pp. 499 ◽  
Author(s):  
MH Campbell ◽  
BR Milne ◽  
JJ Dellow ◽  
HI Nicol
Keyword(s):  
Hypericum Perforatum ◽  
New South ◽  
Arable Land ◽  
Ground Cover ◽  
Aerial Application ◽  
St John’S Wort ◽  
Strong Trend ◽  
St John's Wort ◽  
South Wales ◽  
Hypericum Perforatum L

The effect of type of herbicide and time and rate of application on the reduction in ground cover of St John's wort (Hypericum perforatum L.) was determined at Orange, New South Wales. In January, April, July and November 1988, 8 herbicide treatments including the currently used glyphosate and picloram + 2,4-D were applied to vigorously growing H. perforaturn, and the reduction in percentage ground cover was recorded in December 1989. Ineffective herbicides (a.i./ha) were tebuthiuron, 0.8-6.4 kg; metsulfuron, 5-20 g; and paraquat + diquat, 0.4 + 0.5 kg. The addition of metsulfuron (2.5 g a.i./ha) to glyphosate (0.9 and 1.8 kg a.i./ha) did not increase the effectiveness of the latter. Effective herbicides (kg a.i./ha) were triclopyr + picloram, 0.6 + 0.2; picloram + 2,4-D, 0.2 + 0.8; glyphosate, 1.8; and triclopyr, 1.92. There was a strong trend for these herbicides to be more effective in January and November than in April and July. Based on price, effectiveness and selectivity, triclopyr + picloram would be preferred to the other herbicides for boom and spot spraying, and glyphosate would be the only herbicide suitable for aerial application prior to sowing improved pastures on non-arable land.

EXTRACTION OF HYPERFORIN AND HYPERICIN FROM ST. JOHN'S WORT (HYPERICUM PERFORATUM L.) WITH DIFFERENT SOLVENTS

2011 ◽  
Vol 35 (2) ◽  
pp. 222-235 ◽  
Author(s):  
DÁNIEL COSSUTA ◽  
TÜNDE VATAI ◽  
MÁRIA BÁTHORI ◽  
JUDIT HOHMANN ◽  
TIBOR KEVE ◽  
...  
Keyword(s):  
Hypericum Perforatum ◽  
St John’S Wort ◽  
St John's Wort ◽  
Hypericum Perforatum L

scholarly journals Extraction of resinoids from St. John's wort (Hypericum perforatum L): I. Efficiency and optimization of extraction

2002 ◽  
Vol 56 (2) ◽  
pp. 54-59 ◽  
Author(s):  
Dragan Milenovic ◽  
Vlada Veljkovic ◽  
Branimir Todorovic ◽  
Miomir Stankovic
Keyword(s):  
Plant Material ◽  
Hypericum Perforatum ◽  
Ethanol Solution ◽  
Operating Conditions ◽  
Solvent Ratio ◽  
Total Extract ◽  
St John’S Wort ◽  
St John's Wort ◽  
Hypericum Perforatum L ◽  
Full Factorial

The extraction of resinoids from St. John's wort (Hypericum perforatum L) was studied in a series of two papers. In the first part, the effects of the operating conditions on the yield of resinoids (total extract) were analyzed, while the mathematical models of extraction kinetics were compared in the second one. The extraction was carried out using an aqueous solution of ethanol (70 and 95 % v/v) at a hydromodulus (plant material to solvent ratio, w/v) of 1:5 or 1:10. The plant material was disintegrated and divided into three fractions (mean particle size: 0.23, 0.57 and 1.05 mm). The temperature was 25, 50 or about 80?C (boiling temperature). A higher yield of resinoids was obtained when the plant material of greater disintegration degree (0.23 mm) was treated with 70% v/v aqueous ethanol solution at higher hydromoduli (1:10) and temperatures (80?C). The effects of the operating factors on the yield of resinoids were estimated by using both the full factorial experimental plan 24 and artificial neuronic networks (ANN) of 3-4-1 topology. Of the two methods, the ANN one was found to be advantageous because of its capability of estimating the yield of resinoids in the whole range of the applied operating conditions.

Heavy Metal Contents of St. John’s wort (Hypericum perforatum L.) Growing in Northern Turkey

2006 ◽  
Vol 1 (3) ◽  
pp. 182-186 ◽  
Author(s):  
Ali Kemal Ayan ◽  
Ridvan Kizilkaya . ◽  
Cuneyt Cirak . ◽  
Kudret Kevseroglu .
Keyword(s):  
Heavy Metal ◽  
Hypericum Perforatum ◽  
St John’S Wort ◽  
St John's Wort ◽  
Metal Contents ◽  
Hypericum Perforatum L
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