scholarly journals Control of brown rat (Rattus norvegicus) on a dairy farm in Serbia

2012 ◽  
Vol 28 (3) ◽  
pp. 623-633
Author(s):  
S. Djedovic ◽  
M. Vuksa ◽  
M.M. Petrovic ◽  
J. Bojkovski ◽  
I. Pavlovic ◽  
...  
Keyword(s):  
Rattus Norvegicus ◽  
Sodium Selenite ◽  
Dairy Farm ◽  
Environmentally Friendly ◽  
Economic Damage ◽  
First Year ◽  
High Efficacy ◽  
The Third ◽  
Brown Rat ◽  
Active Substances

Rattus norvegicus is a synanthropic species living almost exclusively around facilities for keeping domestic animals. This three-year research focused on options for reducing economic damage caused by this rodent species in stables for heavy milking cows by testing preparations with active substances of various origin. It involved an environmentally friendly product based on sodium selenite 0.1%, a cholecalciferol-based natural product 0.75%, as well as anticoagulant rodenticides containing the active substances bromadiolone 0.005% and brodifacoum 0.005%. These preparations were formulated as granules, plate bait or grain bait. The environmentally friendly sodium selenite product achieved 76.2% efficacy in the first year of research, 70% in the second, and 67.5% in the third. The synthetic products based on bromadiolone and brodifacoum demonstrated high efficacy in all of the three experimental years and in all three formulations. The cholecalciferol rodenticide had 71.4% efficacy in the first year, 68% in the second, and 67.7% in the third. The data show that the environmentally safe product had a lower efficacy due to high rodent abundance and inadequate epidemiological conditions existing on the farm of heavy milking cows, while the bromadiolone and brodifacoum-based products achieved high efficacy.

1702–1703

2017 ◽  
Author(s):  
Frances Harris
Keyword(s):  
First Year ◽  
The Third

The third chapter traces the beginning of the partnership through the first year of Queen Anne’s reign, as Marlborough persuades Godolphin to return to office as Lord Treasurer and his ministerial partner, with the declared aim of ‘moderation’, that is, holding the balance between the Tories and Whigs on the basis of their support of the war. The role of Queen Anne’s husband Prince George is examined and Marlborough’s and Godolphin’s separate roles are explored, along with the significance of their extensive correspondence. Marlborough is unexpectedly successful in his first campaign, but his determination to obtain a grant from Parliament to support his dukedom jeopardizes Godolphin’s project for war-supply, and their rival Rochester contests control of the Treasury and therefore the war. Marlborough forces Rochester’s resignation and the partnership is confirmed when Marlborough’s only son dies shortly before he leaves for the Continent and he adopts Godolphin’s son as his heir.

scholarly journals Deep learning for intelligent diagnosis in thyroid scintigraphy

2021 ◽  
Vol 49 (1) ◽  
pp. 030006052098284
Author(s):  
Tingting Qiao ◽  
Simin Liu ◽  
Zhijun Cui ◽  
Xiaqing Yu ◽  
Haidong Cai ◽  
...  
Keyword(s):  
Deep Learning ◽  
Disease Diagnosis ◽  
Kappa Coefficient ◽  
Diagnostic Assessment ◽  
First Year ◽  
Thyroid Scintigraphy ◽  
Diagnostic Ability ◽  
The Third ◽  
Classification Time ◽  
Better Than

Objective To construct deep learning (DL) models to improve the accuracy and efficiency of thyroid disease diagnosis by thyroid scintigraphy. Methods We constructed DL models with AlexNet, VGGNet, and ResNet. The models were trained separately with transfer learning. We measured each model’s performance with six indicators: recall, precision, negative predictive value (NPV), specificity, accuracy, and F1-score. We also compared the diagnostic performances of first- and third-year nuclear medicine (NM) residents with assistance from the best-performing DL-based model. The Kappa coefficient and average classification time of each model were compared with those of two NM residents. Results The recall, precision, NPV, specificity, accuracy, and F1-score of the three models ranged from 73.33% to 97.00%. The Kappa coefficient of all three models was >0.710. All models performed better than the first-year NM resident but not as well as the third-year NM resident in terms of diagnostic ability. However, the ResNet model provided “diagnostic assistance” to the NM residents. The models provided results at speeds 400 to 600 times faster than the NM residents. Conclusion DL-based models perform well in diagnostic assessment by thyroid scintigraphy. These models may serve as tools for NM residents in the diagnosis of Graves’ disease and subacute thyroiditis.

scholarly journals AB0751 SAFETY AND PERSISTENCE OF USTEKINUMAB IN PATIENTS WITH PSORIATIC ARTHRITIS IN BIOBADASER

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1672.2-1672
Author(s):  
N. Busquets-Pérez ◽  
C. Sánchez-Piedra ◽  
P. Vela-Casasempere ◽  
M. Freire-Gonzalez ◽  
C. Bohórquez ◽  
...  
Keyword(s):  
Psoriatic Arthritis ◽  
Adverse Events ◽  
First Year ◽  
Line Treatment ◽  
Minimal Disease Activity ◽  
First Line ◽  
The Third ◽  
Minimal Disease ◽  
Second Year ◽  
Third Line

Background:Ustekinumab has been efficacy and safety for psoriatic artritis in clinical trials.Objectives:To assess effectiveness, by means of drug persistence analisys, and safety of ustekinumab in patients with psoriastic arthritis in Biobadaser.Methods:BIOBADASER is the Spanish registry of biological drugs of the Spanish Society of Rheumatology and the Spanish Medicines Agency. We identified patients aged 18 years or more with psoriatic arthritis on Ustekinumab. A descriptive analysis was performed.The persistence of ustekinumab therapy was calculated with a Kaplan-Meier curve and was compared with the persistence of anti-TNF, according to line treatment. Log Rank test was used to establish a comparison. Adverse events occurring with ustekinumab are described according to year treatment.Results:One hundred and twelve patients were on ustekinumab. Most of them were on their second or third line treatment: 53.57% more than one biological therapy (BT), 19.64% second BT, 26.79% were naïve for BT. Most of them were on 45 mg dose: 88.24%. Median duration of disease at Ustekinumab initiation was 10.1 SD 7.2 years; 69.23% had peripheral arthritis; 45.24% had obesity and 39.29% were overweight; 40,6% were on prednisone and 59.82% on DMARD. The cause of discontinuation of treatment was mainly inefficacy (82.61%) and less common an adverse event (6.52%). The probability of persistence of treatment with ustekinumab was 0.83 (95% CI 0.63-0.92) at year 1, 0.79 (0.58-0.90) at year 2 and 0.79 (0.58-0.9) at year 3 when ustekinumab was prescribed as the first line treatment. The persistence decrease when ustekinumab was prescribe as a second and third treatment: being 0.53 (0.27-0.73) the first year, 0.46 (0.22-0.67) the second year and 0.46 (0.22-0.67) as a second line treatment and 0.58 (0.44-0.70) the first year, 0.33 (0.17-0.50) the second year and 0.33 (0.17-0.50) the third year as a third line treatment.The persistence was similar to anti-TNF treatment, according to line treatment. Adverse events were mainly mild (97.83%) and occurred the first year of treatment. Most of the adverse events were classified as “infections and infestations” (36.96%).Conclusion:The persistence of ustekinumab was high, being 83% at the end of the first year on treatment and 79% the second and the third year of treatment. The persistence of ustekinumab was higher when if it was the first line treatment compared as if it was used as the second o third BT option. The persistence of Ustekinumab is similar to the persistence of anti-TNF treatments in all the analyzed treatment lines (no statistically differences were found). Adverse events occurred mainly during the first year treatment. They were mainly mild adverse events and the frequency decreased within the second and third year of treatment.References:[1]Treatment with ustekinumab in a Spanish cohort of patients with psoriasis and psoriatic arthritis in daily clinical practice.Almirall M, Rodriguez J, Mateo L, Carrascosa JM, Notario J, Gallardo F. Clin Rheumatol. 2017 Feb;36(2):439-443;[2]Minimal disease activity in patients with psoriatic arthritis treated with ustekinumab: results from a 24-week real-world study.Napolitano M, Costa L, Caso F, Megna M, Scarpa R, Balato N, Ayala F, Balato A. J Clin Rheumatol. 2018 Oct;24(7):381-384;[3]Minimal Disease Activity and Patient-Acceptable Symptom State in Psoriatic Arthritis: A Real-World Evidence Study With Ustekinumab.Queiro R, Brandy A, Rosado MC, Lorenzo A, Coto P, Carriles C, Alperi M, Ballina J. Actas Dermosifiliogr. 2018 Jun 28;[4]An analysis of Drug Survival, Effectiveness, and Safety in Moderate to Severe Psoriasis Treated With Ustekinumab: An Observational Study of 69 Patients in Routine Clinical Practice.Salgüero Fernández I, Gil MH, Sanz MS, Gullón GR;Disclosure of Interests:None declared

Effect of selenium supplementation on survival, liveweight and wool weight of young sheep on Kangaroo Island, South Australia

1979 ◽  
Vol 19 (101) ◽  
pp. 689 ◽  
Author(s):  
SK Walker ◽  
GP Hall ◽  
DH Smith ◽  
RW Ponzoni ◽  
GJ Judson
Keyword(s):  
Total Dose ◽  
Whole Blood ◽  
Sodium Selenite ◽  
South Australia ◽  
Selenium Concentration ◽  
Mortality Rates ◽  
Selenium Supplementation ◽  
First Year ◽  
Weaning Weight ◽  
Fleece Weight

The responses in liveweight, wool weight and survival, to selenium supplementation, were studied in young sheep from weaning to yearling age. The experiment was conducted over three years. In the first year, one sodium selenite supplementation rate was used (total dose 46.5 mg). During the following two years two supplementation rates were administered (total doses 46.5 mg and 93 mg). Mean concentrations of selenium in whole blood in unsupplemented sheep varied from 0.19-0.56 pmol l-l and from 0.20-0.44 pmol l-1 in the two years in which concentrations were measured. Supplementation, which commenced at lamb marking, increased the selenium concentration in sheep at weaning and thereafter. Selenium supplementation improved the break-of-season weight (P < 0.01) and yearling weight (P < 0.01 ) but not weaning weight (0.05 < P < 0.1 ). Hogget fleece weight was improved (P < 0.01 ) and mortality reduced (P < 0.01) by selenium supplementation. There was a treatment x year interaction in mortality rates (P < 0.01 ). There were no significant differences between the two supplementation rates

scholarly journals Damage to wheat by enclosed populations of Rattus norvegicus

1951 ◽  
Vol 49 (1) ◽  
pp. 22-25 ◽  
Author(s):  
S. A. Barnett
Keyword(s):  
Rattus Norvegicus ◽  
Monetary Loss ◽  
Brown Rat ◽  
The Common

Small enclosed populations of the common brown rat (ten to twenty-six rats), each with access to one ton of sacked wheat for 12–28 weeks, caused a loss in weight of 4·4% of the wheat. 70·4% of the wheat was fouled and had to be cleaned before use. The main monetary loss was due to damage to sacks. Total monetary loss was 18·23% of the original value of the wheat and sacks.

scholarly journals Types of biologically active substances, methods of their application as factors of increasing resistance of varieties of various potatoes in an effort to realize greater productivity when exposed to pathogenic organisms

2021 ◽  
Vol 901 (1) ◽  
pp. 012070
Author(s):  
E P Sevostyanova ◽  
M A Sevostyanov ◽  
A P Glinushkin
Keyword(s):  
Late Blight ◽  
Environmentally Friendly ◽  
Potato Yield ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
The World ◽  
Average Loss ◽  
Potato Famine ◽  
Active Substances ◽  
Resistance Of Varieties

Abstract All countries in the world strive not to repeat the potato famine of Ireland. Potatoes infect more than 100 pathogens, one of the most serious is late blight. In the world, the average loss of potato yield from late blight is 10-15% per year. This article briefly discusses various safe, effective and environmentally friendly methods of preventing and controlling late blight of potatoes.

scholarly journals Gamificação no ensino de astronomia

2020 ◽  
Vol 4 (4) ◽  
pp. 623-639
Author(s):  
Roger Broetto Rocha ◽  
Lucio Martins Fassini Da Silva ◽  
Cleiton Kenup Piumbini ◽  
Luiz Otavio Buffon ◽  
Marconi Frank Barros
Keyword(s):  
High School ◽  
First Year ◽  
The Third ◽  
Third Stage ◽  
The Subject ◽  
Three Stages ◽  
The City

Resumo: Este trabalho tem por objetivo relatar uma atividade didática, realizada no Programa Institucional de Bolsas de Iniciação à Docência (PIBID), envolvendo o ensino de Astronomia numa turma do primeiro ano do ensino médio de uma escola do município de Vitória, ES. A atividade foi planejada e executada pelo subprojeto do Curso de Licenciatura em Física do IFES – Campus Cariacica. A metodologia foi baseada na Gamificação aplicada ao ensino-aprendizagem. A intervenção ocorreu em três etapas, sendo a primeira realizada em dois encontros, através de apresentações dialogadas sobre Astronomia usando slides e gifs, a segunda consistiu na aplicação da Gamificação através de um jogo e finalizando com a terceira etapa, foi aplicado um pequeno questionário. Ao final houve um momento de avaliação e as análises constataram que o ensino de Astronomia através da atividade gamificada do jogo conseguiu motivar os alunos, despertar o interesse pelo assunto e produzir indícios de aprendizagem.Palavras-chave: Gamificação em sala de aula; Ensino de Astronomia; PIBID. Gamification in astronomy teachingAbstract: This work aims to report on a didactic activity, carried out in the Institutional Program for Teaching Initiation Scholarships (PIBID), involving the teaching of Astronomy in a class of the first year of high school at a school in the city of Vitória, ES. The activity was carried out by the subproject of the Physics Degree Course at IFES - Campus Cariacica. The intervention took place in three stages, the first being in two meetings, through dialogued presentations on Astronomy using slides and gifs, the second consisted of the application of Gamification through a game and ending with the third stage, a small questionnaire was applied. At the end there was a moment of evaluation and the analyzes found that the teaching of Astronomy through the gamified activity of the game managed to motivate students, arouse interest in the subject and produce evidence of learning.Keywords: Gamification activity in the classroom; Astronomy teaching; PIBID. 

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