scholarly journals Biochemical effects induced by deoxynivalenol intoxication in piglets

2007 ◽  
Vol 23 (5-6-2) ◽  
pp. 245-250 ◽  
Author(s):  
A. Dinischiotu ◽  
D. Dinu ◽  
M. Rebedea ◽  
G. Stoian ◽  
I. Taranu ◽  
...  
Keyword(s):  
Biochemical Parameters ◽  
Gamma Glutamyl Transferase ◽  
Serum Urea ◽  
Serum Total Protein ◽  
Biochemical Effects ◽  
Significant Difference ◽  
Serum Biochemical ◽  
Glutamyl Transferase ◽  
Aspartate Transferase ◽  
Sera Samples

Thirty-5 weeks-old pigs were fed corn-soybean diets containing 0.5 ppm and 1.5 ppm. deoxynivalenol. Sera samples were collected from ten piglets in each group at the end of 35 days of the trial to study the effect of certain serum biochemical parameters. Highly significant (P < 0.05) differences were observed for serum urea and gamma glutamyl transferase between control and mycotoxin treated groups. Mycotoxin treated groups did not reveal any significant difference for serum total protein, albumin, globulin, aspartate transferase and alanine transferase.

scholarly journals Gene EBNA3C: Type of Infection by EBV (EBV1 and EBV2) Correlation With Clinical and Biochemical Parameters (AST, ALT and GGT) in Individuals With Infectious Mononucleosis in the Metropolitan Area of Belém, Pará, 2005-2016

2019 ◽  
Author(s):  
Talita Antonia Furtado Monteiro ◽  
Iran Barros Costa ◽  
Igor Brasil Costa ◽  
Thais Letícia dos Santos Corrêa ◽  
Beatriz Monteiro Rodrigues Coelho ◽  
...  
Keyword(s):  
Infectious Mononucleosis ◽  
Biochemical Parameters ◽  
Clinical Signs ◽  
Cervical Lymphadenopathy ◽  
Metropolitan Region ◽  
Gamma Glutamyl Transferase ◽  
Barr Virus ◽  
Significant Difference ◽  
Epstein Barr ◽  
Glutamyl Transferase

Abstract Background: Two types of Epstein Barr virus (EBV1 and 2) have been shown to infect humans. This study aimed to detect the types of EBV that cause infectious mononucleosis and correlate these viral types with clinical parameters in the metropolitan region of Belém from 2005 to 2016.Methods: A total of 76 cases of infectious mononucleosis (IM) were processed at the Instituto Evandro Chagas, Ananindeua, Brazil. PCR was used to analyze the EBNA 3C region for the recognition of EBV types. Biochemical testing (aspartate aminotransferase (AST), alanine aminotransferase (ALT) and gamma-glutamyl transferase (GGT) was performed by the COBAS INTEGRA clinical biochemistry PLUS 400 / ROCHE automatic analyzer. The data were evaluated using the Statistical Package for Social Science - SPSS 17.0 and GraphPadPrism 7.0 for Windows.Results: EBV1 infection was observed in 71.1% (54/76) of individuals, among whom those > 14 years constituted 66.7% (36/54); the average age was 23 years, and the number of women infected was higher (61.1% [33/54]) than that of men 38.9%[21/54]). The symptoms/clinical signs observed in infection by EBV1 were cervical lymphadenopathy in 64.8% (35/54), fever in 63% (34/54), headache and arthralgia in 20.3% (11/54), and exanthema in 18.5% (10/54). Infection by EBV2 was observed in only 17.1% (13/76) of cases. Coinfections by EBV1 and EBV2, most frequently showing symptoms of fever and cervical lymphadenopathy, occurred in 66.7% (6/9) and 55.6% (5/9) of individuals. Alterations to AST were confirmed in 14.8% (8/54), EBV2 of cases in 7.7% (1/13) in EBV1 infection. Conclusions: EBV1 was predominant in 71% of clinical cases of infectious mononucleosis. The correlation of biochemical parameters in infection by EBV1, EBV2, and coinfections by EBV1/2 revealed a statistically significant difference in mean changes of EBV1 in individuals older than 14 years.

scholarly journals Gene EBNA3C: Type of Infection by EBV (EBV1 and EBV2) Correlation With Clinical and Biochemical Parameters (AST, ALT and GGT) in Individuals With Infectious Mononucleosis in the Metropolitan Area of Belém, Pará, 2005-2016

2019 ◽  
Author(s):  
Talita Antonia Furtado Monteiro ◽  
Iran Barros Costa ◽  
Igor Brasil Costa ◽  
Thais Letícia dos Santos Corrêa ◽  
Beatriz Monteiro Rodrigues Coelho ◽  
...  
Keyword(s):  
Infectious Mononucleosis ◽  
Biochemical Parameters ◽  
Clinical Signs ◽  
Cervical Lymphadenopathy ◽  
Metropolitan Region ◽  
Gamma Glutamyl Transferase ◽  
Barr Virus ◽  
Significant Difference ◽  
Epstein Barr ◽  
Glutamyl Transferase

Abstract Background: Two types of Epstein Barr virus (EBV1 and 2) have been shown to infect humans. This study aimed to detect the types of EBV that cause infectious mononucleosis and correlate these viral types with clinical parameters in the metropolitan region of Belém from 2005 to 2016.Methods: A total of 76 cases of infectious mononucleosis (IM) were processed at the Instituto Evandro Chagas, Ananindeua, Brazil. PCR was used to analyze the EBNA 3C region for the recognition of EBV types. Biochemical testing (aspartate aminotransferase (AST), alanine aminotransferase (ALT) and gamma-glutamyl transferase (GGT) was performed by the COBAS INTEGRA clinical biochemistry PLUS 400 / ROCHE automatic analyzer. The data were evaluated using the Statistical Package for Social Science - SPSS 17.0 and GraphPadPrism 7.0 for Windows.Results: EBV1 infection was observed in 71.1% (54/76) of individuals, among whom those > 14 years constituted 66.7% (36/54); the average age was 23 years, and the number of women infected was higher (61.1% [33/54]) than that of men 38.9%[21/54]). The symptoms/clinical signs observed in infection by EBV1 were cervical lymphadenopathy in 64.8% (35/54), fever in 63% (34/54), headache and arthralgia in 20.3% (11/54), and exanthema in 18.5% (10/54). Infection by EBV2 was observed in only 17.1% (13/76) of cases. Coinfections by EBV1 and EBV2, most frequently showing symptoms of fever and cervical lymphadenopathy, occurred in 66.7% (6/9) and 55.6% (5/9) of individuals. Alterations to AST were confirmed in 14.8% (8/54), EBV2 of cases in 7.7% (1/13) in EBV1 infection. Conclusions: EBV1 was predominant in 71% of clinical cases of infectious mononucleosis. The correlation of biochemical parameters in infection by EBV1, EBV2, and coinfections by EBV1/2 revealed a statistically significant difference in mean changes of EBV1 in individuals older than 14 years.

scholarly journals Relationship between certain serum biochemical values and serostatus against Anaplasma marginale in dairy cows

2019 ◽  
Vol 12 (11) ◽  
pp. 1858-1861
Author(s):  
Myassar O. Alekish ◽  
Zuhair Bani Ismail
Keyword(s):  
Dairy Cows ◽  
Total Protein ◽  
Biochemical Parameters ◽  
Anaplasma Marginale ◽  
Fatty Degeneration ◽  
Enzyme Linked Immunosorbent Assay ◽  
Gamma Glutamyl Transferase ◽  
Serum Samples ◽  
Serum Biochemical ◽  
Glutamyl Transferase

Aim: This study was conducted to evaluate the possible association between values of certain serum biochemical parameters and seropositivity against Anaplasma marginale in dairy cows. Materials and Methods: Serum samples from 60 seropositive and 40 seronegative cows were used to determine the values of beta-hydroxybutyrate (BHB), glucose, creatinine, blood urea nitrogen, total protein, albumin, alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine transaminase (ALT), lactate dehydrogenase (LDH), and gamma-glutamyl transferase (GGT) using commercially available kits and reagents. The serostatus of cows against A. marginale was determined using a commercially available cellular enzyme-linked immunosorbent assay kit according to the manufacturer's recommendations. Significant differences in serum biochemical values between seropositive and seronegative groups were evaluated using independent Student's t-test. Possible associations between the serostatus of the cows and different biochemical parameters were evaluated using univariate followed by multivariate logistic regression analyses. Results: There was a statistically significant increase (p≤0.05) in values of total protein, BHB, LDH, and AST in seropositive cows compared to seronegative cows while a non-significant increase in values of ALP, ALT, and GGT was detected in seropositive cows. A strong correlation (R=0.69) between serum levels of BHB, LDH, and AST and seropositivity against A. marginale was detected. Conclusion: There is evidence of a possible association between A. marginale infection and liver damage/hepatic fatty degeneration in dairy cows. Further studies, however, are required to elucidate the exact pathophysiological mechanisms of this relationship.

ESTABLISHING IN-HOUSE REFERENCE INTERVALS FOR DOGS IN VETERINARY CLINICS

2016 ◽  
Vol 42 (02) ◽  
pp. 53-67
Author(s):  
Shang-Hsiu Chung ◽  
Li-Wen Chang ◽  
Tsun-Li Cheng ◽  
Chen-Jou Lin ◽  
Wen-Ying Chen ◽  
...  
Keyword(s):  
Uric Acid ◽  
Bile Acid ◽  
Biochemical Parameters ◽  
Clinical Pathology ◽  
Reference Interval ◽  
Reference Intervals ◽  
Gamma Glutamyl Transferase ◽  
Coagulation Parameters ◽  
American Society ◽  
Glutamyl Transferase

Reference interval (RIs) were critical to the identification of illness. However, RIs set in one laboratory may not be appropriate for another because of biological, geographical and instrumental factors. Interpretation of clinical data using inappropriate RIs may cause misclassification of results and misdiagnosis that lead to improper treatment. RIs in Taiwan have been mostly referencing from foreign resources, it is desirable to establish one that is closer to the overall conditions in Taiwan (such as breed, climate, diseases, etc.) and to investigate its differences to foreign RIs. The present study used the American Society for Veterinary Clinical Pathology (ASVCP) guidelines to establish in-house RIs for hematological, biochemical and coagulation parameters using dogs in middle Taiwan. The results were also compared to two foreign and one local RIs. The results suggested that the hematological RIs are more comparable to foreign RIs than the biochemical and hemostatic parameters. Differences were found for biochemical parameters including gamma-glutamyl transferase (GGT), lactate dehydrogenase (LDH), lipase, uric acid, bile acid, bilirubin and magnesium; and coagulation parameters including prothrombin time (PT) and activated partial thromboplastin. In all, 18% (7/40) of the all tested parameters were different from the local RI while 38% (18/48) and 41% (19/46) of the parameters were different from the two foreign RIs. The differences in more than 30% RIs and better similarities to local RIs underscore the importance of having own RIs if possible.

scholarly journals Age – Related changes in serum biochemical parameters in the domestic rabbit (Oryctolagus cuniculus)

2020 ◽  
Vol 45 (5) ◽  
pp. 67-71
Author(s):  
K. A. Adebisi
Keyword(s):  
Total Protein ◽  
Biochemical Parameters ◽  
Serum Biochemistry ◽  
Serum Biochemical Parameters ◽  
Serum Total Protein ◽  
Domestic Rabbit ◽  
Age Related ◽  
Protein 4.2 ◽  
Pubertal Stages ◽  
Serum Biochemical

The influence of age on serum biochemical components in the domestic rabbit was investigated. The serum total protein (g/dL), albumin (g/dL), globulin (g/dL), creatinine (mg/dL), urea mg/dL, cholesterol (mg/dL), Alkaline phosphatase (ALP; iu/l), Aspartate aminotranferase (AST; iu/l) and Alanine amimotransferase (ALT; iu/l) were assessed in 24 male rabbits at 7, 14 and 21 weeks of age to represent weaners, growers and pubertal stages. Data were analysed using descriptive statistics and analysis of variance at á . Results of 0.05 serum biochemistry revealed a steady significant increase in total protein (4.2±0.3; 5.3±0.5; 6.9±0.2), albumin (2.2±0.7; 2.8±0.4; 4.0±0.2), globulin (1.9±0.3; 2.5±0.4, 2.9±0.2), cholesterol (49.5±1.1; 56.4±4.2; 62.4±5.4) and creatinine (0.8±0.1; 1.2±0.1; 1.9±0.3) at 7, 14 and 21 weeks respectively. Serum urea levels were similar across the ages. The values recorded for ALP and AST at 7 weeks (39.6±7.5; 101.1±6.7) and 14 weeks (38.7±6.4; 104.5±8.7) were significantly higher than the 21 weeks (33.5±2.7; 95.8±5.9) while ALT at 7 weeks (27.33±5.6) was significantly lower than 14 (38.2±3.9) and 21 weeks (37.4±3.0). The age of the rabbits had a significant effect on their serum biochemical parameters. They should therefore be grouped according to age when setting serum reference values for them.

scholarly journals Effects of Artemisia herba-alba or olive leaf (Olea europaea) powder supplementation on growth performance, carcass yield, and blood biochemical parameters in broilers

2018 ◽  
pp. 1624-1629
Author(s):  
Asma Ait-Kaki ◽  
Mamadou Tandiang Diaw ◽  
Fikremariam Geda ◽  
Nassim Moula
Keyword(s):  
Growth Performance ◽  
Biochemical Parameters ◽  
Olive Leaf ◽  
Carcass Yield ◽  
Blood Biochemical ◽  
Significant Difference ◽  
Leaf Powder ◽  
Serum Biochemical ◽  
Group 3 ◽  
Group 1

Aim: This study was aimed to evaluate the effects of Artemisia herba-alba (white wormwood) or olive leaf (Olea europaea) powder supplementation on growth performance, carcass yield, and serum biochemical parameters in broilers. Materials and Methods: The study was conducted from April to May 2017 in Chemini region, Northern Algeria. A total of 60 1-day-old Ross 308 male chicks were divided into three groups consisted of 10 chicks, in each of two replications. The chicks in Group 1 were fed with a standard commercial diet (SCD); Group 2 received the same SCD with 2% supplementation of A. herba-alba powder; and Group 3 received the same SCD with 2% supplementation of O. europaea powder. Growth performance was measured with body weights every 2 weeks, daily feed intake, feed conversion ratio (FCR), and carcass yield at the end of 42 days of rearing. Blood samples were collected to analyze serum glucose, cholesterol, triglycerides, urea, and total protein levels. Results: Results showed that, at 42 days of rearing, supplementation of O. europaea and A. herba-alba significantly increased (p<0.001) mean body weight (2230.10±26.38 g and 2117.42±26.38 g, respectively, vs. 2336.66±27.88 g in chicks of Group 1), but there was no significant difference (p≥0.05) among the three diets for FCR or percentage carcass yield. Among the serum biochemical parameters, glucose was significantly affected (p<0.01) by supplementation of olive leaf powder (1.90 g/L: Group 3), compared to the SCD (2.24 g/L: Group 1) or Artemisia powder (2.05 g/L: Group 2). Moreover, the supplementation of olive leaf powder in Group 3 broilers significantly affected (p<0.05) the serum cholesterol level (0.95 g/L), compared to the control diet (1.13 g/L). There was no significant difference (p≥0.05) for the other selected serum biochemical concentrations, namely triglycerides, urea, and total protein. Conclusion: The supplementation of Artemisia or olive leaf powder into the diet for broilers improved body weight by about 5% or 10%, respectively, at slaughter with moderate changes in blood biochemical parameters.

scholarly journals Influence of salicylate administration on weight gain and serum biochemical parameters in broiler chickens

2010 ◽  
Vol 66 (10) ◽  
pp. 675-679 ◽  
Author(s):  
Poźniak B. ◽  
Yuan H. ◽  
J. Yi ◽  
Guo C. ◽  
Deng S. ◽  
...  
Keyword(s):  
Body Weight ◽  
Total Protein ◽  
Biochemical Parameters ◽  
Broiler Chickens ◽  
Clinical Manifestations ◽  
Weight Ratio ◽  
Serum Biochemical Parameters ◽  
Serum Total Protein ◽  
Weight Gains ◽  
Serum Biochemical

The aim of the study was to investigate the effects of different doses of acetylsalicylic acid (ASA) and sodium salicylate (SS) administration on weight gains and serum biochemical parameters in broiler chickens. This study was performed to investigate the safety of ASA and SS in chickens in conditions of moderate overdose. Seventy five broiler chickens (Sanhuangji breed) were divided into control and experimental groups. The chickens were administered orally with ASA or SS in the following daily doses: 50, 100 and 200 mg/kg for 20 days. In the course of the experiment weight gains were recorded. On day 14 and day 20 the chickens were sampled for blood biochemical analysis. Investigated parameters included serum total protein, albumin, uric acid, creatinine, potassium, sodium and calcium contents as well as alanine transaminase activity. After the last samplings the chickens were dissected and liver and kidney to body weight ratios were recorded. It was demonstrated that SS at a dose of 200 mg/kg increased serum total protein level. ASA increased serum proteins at a dose of 100 mg/kg but not at a higher dose. At the dose of 200 mg/kg ASA increased the kidney to body weight ratio. In all salicylate treated groups the liver weights were lower as compared to the control. No clinical manifestations of intolerance were observed. It is assumed that chickens tolerate ASA and SS well, even in doses producing distinct side effects in several mammalian species.

scholarly journals Study of High sensitive C - reactive protein and Gamma-glutamyl transferase in Type 2 Diabetes Mellitus with Hypertension

2020 ◽  
Vol 11 (3) ◽  
pp. 3478-3483
Author(s):  
Ramya S ◽  
Sureka Varalakshmi V ◽  
Uma Maheswari K ◽  
Chandan Bala R
Keyword(s):  
Diabetes Mellitus ◽  
Gamma Glutamyl Transferase ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Significant Difference ◽  
Group A ◽  
Hs Crp ◽  
Group B ◽  
Glutamyl Transferase

C-reactive protein (CRP), produced by the hepatocytes is a primary inflammatory marker of T2DM. Higher levels of gamma-glutamyl transferase enzyme (GGT) and Hs CRP (High sensitive CRP)are associated with the complication of poor glycemic control.This study was aimed to find the association of Hs CRP and GGT for cardiovascular risk factors in Type 2 diabetes mellitus (T2DM)and Hypertension in the suburbs of Chennai. This study includes 57 subjects with T2DM and Hypertension (Group A) and 62 subjects with T2DM (GroupB) within the age group of 40-60 years. FBS, HbA1C, Hs CRP, GGT and blood pressure were determined. Statistical analysis was performed using Statistical Package for the SPSS 17 version. Mean values of FBS, blood HbA1C, Hs CRP and GGT were significantly higher among participants of Group A than Group B. Significant difference of FBS, HbA1C were found between the two groups. In contrast, no significant difference of GGT was found between the groups. Differences were considered statistically significant at two-sided P < 0.05. Within the group, Hs CRP shows the significance and positive correlation with FBS, SBP and DBP. Still, GGT does not show any significance in Group A. In contrast, in Group B, both Hs CRP and GGT shows the importance and positive correlation with FBS and HbA1C.It is concluded that high levels of HsCRP are associated with T2DM and Hypertension, indicating increased cardiovascular risk, and it should be included in regular monitoring of type-2 diabetic patients.

scholarly journals Comparative study of some Serum Biochemical parameters of cattle and sheep of the marshes in the south of Iraq

2010 ◽  
Vol 9 (2) ◽  
pp. 78 ◽  
Author(s):  
Kh. G. Al-Fartosi, Y. J. Talib, and Sh. Ali
Keyword(s):  
Biochemical Parameters ◽  
Serum Levels ◽  
Serum Glucose ◽  
The South ◽  
Male And Female ◽  
Significant Difference ◽  
Serum Biochemical ◽  
South Of Iraq ◽  
Female Cattle ◽  
Cattle And Sheep

This study includes the normal values of biochemical parameters of cattle and sheep lived in Marshes of the south of Iraq. The serum levels of glucose, urea, creatinine, cholesterol, triglyceride, total protein, albumin, globulin, calcium(ca), potassium(k), Aspartate aminotransferase(AST), Alanine aminotransferase (ALT), Alkaline phosphatase ( ALP) and Lactate dehydrogenase (LDH) were determined.T he results showed there are nonsignificant differences in all parameters of male cattle compared with a female, except the serum glucose which decreased significantly in male compared with female. There is a significant increase in cholesterol and potassium of male sheep compared with a female, whereas the other parameters did not show a significant difference (p<0.05) between them. also, the results indicated a significant increase in TG, cholesterol, AST, ALK, and LDH of male and female cattle compared with male and female sheep. There were no significant differences in other parameters.

scholarly journals Clinical-biochemical status of hens due to changes of battery cages height location

2021 ◽  
Vol 9 (3) ◽  
pp. 130-134
Author(s):  
M. I. Sakhatsky ◽  
Yu. V. Osadcha
Keyword(s):  
Blood Serum ◽  
Chronic Stress ◽  
Biochemical Parameters ◽  
Physiological State ◽  
Serum Enzymes ◽  
The Body ◽  
Gamma Glutamyl Transferase ◽  
Biochemical Status ◽  
Battery Cages ◽  
Glutamyl Transferase

In the conditions of industrial poultry farming, the body of hens is constantly exposed to numerous technological stressors, the least studied of which are long-term ones, that can provoke chronic stress. One such technological stressor is an increase in the level of cage equipment, which is used by producers to obtain a larger amount of products from 1 m2 of poultry area. The aim of this work was to study the physiological state of the hen’s body based on the clinical biochemical analysis of their blood serum, depending on the battery cages height. In the conditions of a modern complex for the production of edible eggs in a poultry house with an area of 2 915 m2, 4 groups of hens were formed, each of them was kept on a separate floor-analogue in terms of area and cage equipment. Each floor was equipped with «Big Dutchman» 3-tier battery cages. Battery cages of each floor were separated from each other by a lattice floor so that cages of 1–3 tiers entered up to the 1st floor, 4–6 tiers – up to the 2nd, 7–9 tiers – up to the 3rd, and 10–12 tiers – up to 4th floor of cage equipment. Biochemical parameters and activity of hens blood serum enzymes were determined on a BioChem FC-360 biochemical analyzer. For this, 30 blood samples with a volume of 1.0–1.5 ml were taken from axillary veins of laying hens in each group at the age of 18 weeks (at the beginning of the study) and at 52 weeks. It was found that increasing the layering of cage equipment does not have a negative impact on the hen’s body. So, for keeping hens in cages of multi-tier battery cages located on floors 2–4 (4–12 tiers), the biochemical status and activity of their blood serum enzymes were within the physiological norm. Whereas, for hens kept in battery cages of the a multi-tiered system on the 1st floor there was an increase in glucose levels of 60.5–71.0%, creatinine – by 9.7–12.3%, phosphorus – 82.6–100.0%, was observed a decrease in calcium to phosphorus ratio 46.7–50.0%, which was confirmed by an increase in the activity of alkaline phosphatase by 22.3–27.0%, as well as an increase in the activity of aspartate aminotransferase by 3.2–13.8%, lactate dehydrogenase - by 48.5–65.1% and gamma-glutamyl transferase – by 16.4–20.6%. It has been proven that the main consequences of chronic stress caused by keeping hens in the lower floor cells of the multi-tiered battery cage are reflected in the biochemical parameters of their serum, namely increased glucose, creatinine, enzyme activity and violation of calcium to phosphorus ratio.

Sign in / Sign up

Export Citation Format

Share Document