Large tumor forming Pseudoangiomatous stromal hyperplasia of the breast: A case report

2013 ◽  
Vol 21 (3-4) ◽  
pp. 131-132
Author(s):  
Snezana Bozanic ◽  
Nenad Solajic ◽  
Miljan Milic ◽  
Tomislav Petrovic

Pseudoangiomatous stromal hyperplasia (PASH) is a benign mesenchymal proliferation with numerous slit-like spaces lined by spindle cells. This is not an uncommon finding showing small microscopic foci, but tumor-forming PASH is rare, especially in postmenopausal women. It has to be distinguished from other benign and malignant tumor, especially from low-grade angiosarcoma. The recommended treatment is wide local excision.

2019 ◽  
Vol 7 ◽  
pp. 2050313X1984778
Author(s):  
Ann M John ◽  
Gina Francisco ◽  
Radhika Srivastava ◽  
Hamza Bhatti ◽  
Babar K Rao

Dermatofibrosarcoma protuberans is an uncommon low-grade malignant tumor that can invade locally and rarely metastasize. Dermatofibrosarcoma protuberans has a high rate of local recurrence due to incomplete excision, especially in deep tissues. Morbidity is often related to multiple local recurrences and removal of excessive tissue with large, complex repairs. We present a case of incompletely excised dermatofibrosarcoma protuberans after initial wide local excision. We subsequently employed a “deep” vertical Mohs micrographic surgical technique to remove the remaining tumor while creating a flap with the tumor-free superficial portion to preserve tissue and avoid a complicated repair. The patient is tumor-free for 7 years.


2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Byung Jun Kim ◽  
Hyeonwoo Kim ◽  
Ung Sik Jin ◽  
Kyung Won Minn ◽  
Hak Chang

Background. Dermatofibrosarcoma protuberans (DFSP), a rare low-grade sarcoma of fibroblast origin, tends to extend in a finger-like fashion beyond macroscopic tumor margins. Therefore, incomplete removal and subsequent recurrence are common. This study aimed to determine the efficacy of wide local excision (WLE) for controlling local recurrence of DFSP.Methods. The medical records of 90 DFSP patients who received WLE at our hospital between June 1992 and January 2015 were retrospectively reviewed. WLE was conducted including a 3 cm (range, 1 to 5 cm) safety margin according to tumor size, location, and recurrence status. Clinical and tumor characteristics and surgical methods were evaluated for risk factor analysis and local recurrence-free survival.Results. DFSP occurred most often in patients in their 30s (30%) and on the trunk (51.1%). Five patients (5.5%) experienced local recurrence during the 43.4-month follow-up period. Recurrence was found at a mean of 10.8 months after WLE. Although no factors were significantly associated with recurrence, recurrences were more frequent in head and neck. Recurrence-free survival was 87% in 6 years and 77% in 7 years.Conclusions. WLE with adequate lateral and deep margins can effectively control local recurrence rate and is a simple and effective method to treat DFSP.


2021 ◽  
Vol 8 ◽  
Author(s):  
Weidong Zhang ◽  
Yuanyuan Liu ◽  
Yamei Chai ◽  
Kefeng Shi ◽  
Jialing Chen ◽  
...  

Pulmonary sclerosing pneumocytoma (PSP) is a rare benign or low-grade malignant tumor, but it has the potential to present with multiple lesions, lymph node metastasis, extra-pulmonary metastasis, recurrence and even cause death. Herein, a case of PSP that was huge, presented with multiple lesions and had lymph node as well as extrapulmonary metastases (liver, abdominal cavity, bones) is reported for the first time. This patient was also the first one to die of respiratory and circulatory failure caused by the PSP tumor and its metastases which compressed the mediastinal tissue.


2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Haider Alyousef ◽  
Elsawi M. Osman ◽  
Mohamed A. Gomha

Introduction. Liposarcoma is a rare pathological entity. By far it is the most common histological subtype of genitourinary sarcomas in adults. Approximately two hundred cases were reported in the literature. We are hereby presenting a case with a typical clinical scenario of paratesticular liposarcoma.Case report. A 75-year-old gentleman presented with a painless right hemiscrotal swelling that was progressively increasing in size over the last 6 years. Testicular tumour markers were negative. Imaging showed a heterogenous mass with fat component. Subsequently he underwent wide local excision that included the paratesticular mass along with the right testicle and all right inguinal canal contents up to the deep inguinal ring with the sparing of right illioinguinal nerve. Histopathological examination showed a well differentiated liposarcoma of the spermatic cord. He remained recurrence-free so far after 18 months of followup.Conclusion. Radical orchidectomy with wide local excision comprises the cornerstone of treatment of paratesticular liposarcoma. Due to the rarity of the disease there is no definite universal consensus of opinion as regards the role of radiotherapy and chemotherapy.


2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
R. J. Roewe ◽  
Matthew A. Uhlman ◽  
Nathan A. Bockholt ◽  
Amit Gupta

Basal cell carcinoma of the penis is an extremely rare entity, accounting for less than 0.03% of all basal cell carcinomas. Fortunately, wide local excision of such lesions is generally curative. Fewer than 25 cases have been reported in the literature describing penile basal cell carcinoma. Here we report a case of penile basal cell carcinoma cured with wide local excision.


2017 ◽  
Vol 30 ◽  
pp. 97-100 ◽  
Author(s):  
Mohamed Azzaza ◽  
Houssem Ammar ◽  
Nihed Abdessayed ◽  
Rahul Gupta ◽  
Mohamed Said Nakhli ◽  
...  

2012 ◽  
Vol 2 (4) ◽  
pp. 331-334
Author(s):  
S Shrestha ◽  
CB Pun ◽  
R Basyal ◽  
T Pathak ◽  
S Bastola ◽  
...  

Polymorphous low-grade adenocarcinoma is a rare salivary gland malignant tumor of low aggressiveness, commonly occurring in minor salivary glands. Its origin in major salivary glands is considered exceedingly rare. We report a case of polymorphous low grade adenocarcinoma arising from left parotid in a 21-yearold female patient.Journal of Pathology of Nepal (2012) Vol. 2, 331-334DOI: http://dx.doi.org/10.3126/jpn.v2i4.6890


2021 ◽  
Vol 8 (3) ◽  
pp. 404-407
Author(s):  
Bhuvana Preethi ◽  
Usha Rajesh ◽  
Mala Vijayakrishnan

Uterine leiomyosarcoma is a rare malignant tumor that arises from smooth muscle cells. It comprises of 1% of all uterine malignancy. We report a case of 54 year old Postmenopausal women with 2 episodes of postmenopausal bleeding and was diagnosed with Leiomyosarcoma of uterus.


2015 ◽  
Vol 1 (4) ◽  
pp. 211
Author(s):  
Dr Rajendra Prasad Bugalia ◽  
Anuradha Salvi ◽  
Prashant Garg ◽  
Abhinav Pandey ◽  
Raj Kamal Jenaw

Hemangioma are rare tumor originating from the pericytes, the contractile cells that surround capillaries. This tumor arises from pericapillary cells or pericytes of Zimmerman and can occur anywhere where capillaries are found . Howeverhemangiopericytoma develops mainly in the lower extremities, retroperitoneum or pelvis. The recommended treatment for a hemangiopericytoma is wide excision. Since many benign and malignant diseases occur in the area surrounding the anus, recognizing the presence of this malignant tumor in the presacral space is important in order to avoid inappropriate surgery such as piecemeal excision. We describe a rare case of a hemangiopericytoma in the presacral space. With posterior approach the tumour was completely removed. Pathological examination includingimmunohistologicalstains was consistent with a hemangiopericytoma.


2012 ◽  
Vol 16 (3) ◽  
pp. 187-190 ◽  
Author(s):  
Padmanabhan Dhanasekar ◽  
Vilvapathy Senguttuvan Karthikeyan ◽  
Nagarajan Rajkumar ◽  
Sarath Chandra Sistla ◽  
S. Manwar Ali ◽  
...  

Background: Cutaneous angiosarcoma is a rare tumor of the elderly male, most commonly affecting the head and neck region. It is difficult to differentiate this tumor from hemangiomas, hemangioblastomas, Kaposi sarcoma, squamous cell carcinoma and anaplastic melanomas. Methods: Case report and review of pertinent English medical literature. Case summary: We report a case of a 60-year-old male presenting with multiple nodules over the scalp where a preoperative histopathologic diagnosis of squamous cell carcinoma was made by wedge biopsy from the tumor. Postoperative histopathology and immuno histochemistry of the wide local excision specimen proved the tumor to be cutaneous angiosarcoma and the patient completed adjuvant radiotherapy. He is now on regular follow-up for 1 year without recurrence. Conclusions: Cutaneous angiosarcoma must be kept in mind in view of its rarity especially in extensive involvement of the scalp by malignancy. The primary treatment is wide local excision with adequate skin cover and adjuvant chemotherapy and radiotherapy in positive margins and lymph node metastasis.


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