scholarly journals Early detection of the regional lymph nodes' metastases by biopsy of the guard lymph nodes in melanoma patients - our experience

2002 ◽  
Vol 10 (3) ◽  
pp. 199-199
Author(s):  
Dejan Nikolic ◽  
Nebojsa Ivanovic ◽  
Natasa Ristic ◽  
Aranka Savic ◽  
Miroslav Granic
Keyword(s):  
Early Detection ◽  
Lymph Nodes ◽  
Regional Lymph Nodes ◽  
Melanoma Patients ◽  
Lymph Nodes Metastases

Nuclear morphometry for the prediction of regional lymph nodes metastases in patients with cancer of the larynx

2000 ◽  
Vol 123 (6) ◽  
pp. 770-774 ◽  
Author(s):  
Wiesław Dobroś ◽  
Krzysztof Gil ◽  
Janusz Ryś ◽  
Krystyna Stanisz-Wallis
Keyword(s):  
Lymph Nodes ◽  
Regional Lymph Nodes ◽  
Patients With Cancer ◽  
Nuclear Morphometry ◽  
Lymph Nodes Metastases

Comment on “Preoperative Ultrasound Assessment of Regional Lymph Nodes in Melanoma Patients Does Not Provide Reliable Nodal Staging

2019 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Emma H. A. Stahlie ◽  
Stephanie A. Blankenstein ◽  
Winan J. van Houdt ◽  
Michel W. J. M. Wouters ◽  
Alexander C. J. van Akkooi
Keyword(s):  
Lymph Nodes ◽  
Nodal Staging ◽  
Regional Lymph Nodes ◽  
Preoperative Ultrasound ◽  
Ultrasound Assessment ◽  
Melanoma Patients

In-vitro activation of natural killer cells from regional lymph nodes of melanoma patients with interleukin-2 and interleukin-15

2015 ◽  
Vol 25 (1) ◽  
pp. 22-34 ◽  
Author(s):  
Ana M. Vuletić ◽  
Irena P. Jovanić ◽  
Vladimir B. Jurišić ◽  
Zorka M. Milovanović ◽  
Srđan S. Nikolić ◽  
...  
Keyword(s):  
Natural Killer Cells ◽  
Lymph Nodes ◽  
Natural Killer ◽  
Interleukin 2 ◽  
Regional Lymph Nodes ◽  
Killer Cells ◽  
In Vitro Activation ◽  
Interleukin 15 ◽  
Melanoma Patients

Detection of micrometastases in regional lymph nodes of melanoma patients

1993 ◽  
Vol 3 (1) ◽  
pp. 86
Author(s):  
D. Reintgen ◽  
R. Heller ◽  
C. W. Cruse ◽  
B. King
Keyword(s):  
Lymph Nodes ◽  
Regional Lymph Nodes ◽  
Melanoma Patients

Melanoma with regional lymph nodes metastases

1993 ◽  
Vol 3 (1) ◽  
pp. 103 ◽  
Author(s):  
C. R. Rossi ◽  
A. Vecchiato ◽  
D. Nitti ◽  
A. Seno ◽  
G. Mancino ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Regional Lymph Nodes ◽  
Lymph Nodes Metastases

scholarly journals High Percentage of ADAM-10 Positive Melanoma Cells Correlates with Paucity of Tumor-Infiltrating Lymphocytes but Does Not Predict Prognosis in Cutaneous Melanoma Patients

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Piotr Donizy ◽  
Marcin Zietek ◽  
Marek Leskiewicz ◽  
Agnieszka Halon ◽  
Rafal Matkowski
Keyword(s):  
Lymph Nodes ◽  
Tumor Cells ◽  
Cutaneous Melanoma ◽  
Primary Tumor ◽  
Tumor Infiltrating Lymphocytes ◽  
Regional Lymph Nodes ◽  
Term Survival ◽  
Intracellular Location ◽  
Melanoma Patients ◽  
Infiltrating Lymphocytes

ADAM-10 (CDw156, CD156c, and kuzbanian) is a protein belonging to a superfamily of metalloproteases, enzymes capable of degrading the extracellular matrix. ADAMs have also been shown to be primarily involved in ectodomain cleavage. The aim of the study was to assess the expression and intracellular location of ADAM-10 in 104 primary skin melanomas and 16 metastatic lesions from regional lymph nodes. Also, prognostic significance of ADAM-10 expression in primary tumor cells and metastatic lesion cells was evaluated during 5-year observation. It was revealed that high expression of ADAM-10 positive cells was strictly related with lower intensity of tumor-infiltrating lymphocytes (P=0.037), which suggests that ADAM-10 regulates immunoresponse in melanoma initiation and progression. No statistically significant correlations were found between ADAM-10 expression in primary tumor cells and nodal metastases and other histopathological parameters analyzed. Decreased immunoreactivity of ADAM-10 in cancer cells from regional lymph nodes was correlated with worse prognosis; however this correlation was statistically nonsignificant (P=0.065). Review of the literature shows that our study is the first one ever to describe the significance of ADAM-10 expression in correlation with detailed histopathological parameters of the primary tumor and data on long-term survival of cutaneous melanoma patients.

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