scholarly journals Fluid-attenuated inversion-recovery MR sequence in the evaluation of low-grade astrocytomas

2002 ◽  
Vol 10 (3) ◽  
pp. 183-184
Author(s):  
Tatjana Stosic-Opincal ◽  
Vesna Peric ◽  
Mihail Gavrilov ◽  
Svetlana Gavrilovic
Keyword(s):  
White Matter ◽  
Inversion Recovery ◽  
Low Grade ◽  
Peritumoral Edema ◽  
Local Spread ◽  
Signal Contrast ◽  
Fluid Attenuated Inversion Recovery ◽  
Definition Of ◽  
Signal Intensities ◽  
Better Than

(Conclusion) Flair was found to be better for detection of the lesion and for definition of its margins in comparison with T2W se and PD sequences (6). Comparing with surrounding white matter, tumors on FLAIR images are isointense or hyperintense. Because of the suppression of CSF signal, contrast between FLAIR is currently used for supplementing basic MRI protocols. FLAIR technique may be used as an adjunct to T2W or PD SE imaging and may even replace PD imaging. FLAIR is superior for appreciation of the lesion and for demonstration of its margin. However, peritumoral edema is clearly demonstrated, and the FLAIR images often delineate edema from tumor, and distinguish CSF from a cystic or necrotic component, better than T2W and PD images. In cases when tumor has a cystic or necrotic component, the signal intensities of such areas are different from that of CSF on FLAIR images. FLAIR demonstrates better local spread of the tumor than T2W and PD images.

scholarly journals ANALISIS PERBEDAAN CITRA MRI BRAIN PADA SEKUENT1SE DAN T1FLAIR

SINERGI ◽  
2015 ◽  
Vol 19 (3) ◽  
pp. 206
Author(s):  
Nursama Heru Apriantoro ◽  
Christianni Christianni
Keyword(s):  
White Matter ◽  
Gray Matter ◽  
Spin Echo ◽  
Spinal Fluid ◽  
Inversion Recovery ◽  
Field Of View ◽  
Slice Thickness ◽  
Weighted Image ◽  
Mri Brain ◽  
Fluid Attenuated Inversion Recovery

MRI adalah bagian dari ilmu kedokteran untuk mediagnosa kelainan organ dengan memanfaatkan medan magnet dan pergerakan proton atom hidrogen. Salah satu pemeriksaan MRI adalah pemeriksaan brain. Pemeriksaan MRI brain dapat dilakukan T1 weighted image Spin Echo (T1 SE) atau T1 Fluid Attenuated Inversion Recovery (T1 FLAIR). Kajian dilakukan untuk menentukan perbedaan T1 SE dan T1 FLAIR dari segi citra berdasarkan nilai Rasio Signal terhadap Noise (SNR) dengan MRI GE Type Signa HD xt 1.5 Tesla. Penelitian menggunakan pendekatan kuantitatif.  20 pasien  telah diambil pada pemeriksaan MRI brain pada potongan axial, dengan parameter T1 SE potongan axial dengan parameter Time Repetition (TR) 700 ms, Time Echo (TE) 20 ms, Field of View (FOV) 240 mm, Slice Thickness 5,0 mm, Spacing 1,0 mm, Number of Excitations (NEX) 1, Phase 224, dan total slice 20. T1 FLAIR  parameter TR 3000 ms, TE 13,9 ms, TI 920 ms, FOV 240 mm, slice thickness 5,0 mm, spacing 1,0 mm,   NEX 1, phase 224, dan total slice 20. SNR dihitung pada anatomi brain meliputi CSF (Cerebro Spinal Fluid), White Matter dan Gray Matter. Hasil penelitian kedua sequence tersebut menunjukkan bahwa sequence T1 SE lebih baik daripada sequence T1 FLAIR.

Signal intensity pattern of the normal oculomotor nerve on contrast-enhanced 3D FLAIR at 3.0 T MRI

2020 ◽  
pp. 197140092097091
Author(s):  
Thiparom Sananmuang ◽  
Chanonporn Boonsiriwattanakul ◽  
Theeraphol Panyaping
Keyword(s):  
White Matter ◽  
Signal Intensity ◽  
Intensity Ratio ◽  
Grey Matter ◽  
Three Dimensional ◽  
Oculomotor Nerve ◽  
Inversion Recovery ◽  
Signal Intensity Ratio ◽  
Contrast Enhanced ◽  
Fluid Attenuated Inversion Recovery

Purpose The aim of this study was to depict the signal intensity pattern of the normal oculomotor nerve demonstrated on contrast-enhanced three-dimensional fluid-attenuated inversion recovery images. Materials and methods Eighty-one patients were included in the study. Contrast-enhanced three-dimensional fluid-attenuated inversion recovery images with magnetisation-prepared rapid acquisition were reconstructed and evaluated in the coronal plane. The signal intensity of the cisternal segment of the oculomotor nerve was graded into a visual scale of 1 to 5 as compared to the white matter, grey matter and the pituitary stalk. The signal intensity ratio of the oculomotor nerve was consequently measured. Results By using the visual scale, more than half of the oculomotor nerves showed higher signal intensity than the grey matter signal on contrast-enhanced three-dimensional fluid-attenuated inversion recovery images (59.3–80.2%). It can demonstrate a signal intensity similar to the pituitary stalk (14.8%) by visualisation. None of them showed signal intensity equal to the normal white matter signal. By signal intensity measurement, the mean signal intensity ratio of oculomotor nerves to white matter equals 1.54±0.20 (95% confidence interval (CI) 1.51–1.57); mean signal intensity ratio to grey matter equals 1.16±0.15 (95% CI 1.14–1.18); mean signal intensity ratio to the pituitary stalk equals 0.68±0.10 (95% CI 0.64–0.70). Conclusions The normal oculomotor nerve visualised on contrast-enhanced three-dimensional fluid-attenuated inversion recovery images has a higher signal intensity than the white matter and may have a signal intensity similar to the grey matter or the pituitary stalk. The high signal intensity of the oculomotor nerve in contrast-enhanced three-dimensional fluid-attenuated inversion recovery should not be misinterpreted as a pathology.

Fluid-attenuated inversion-recovery MR imaging in schizophrenia-associated with idiopathic unconjugated hyperbilirubinemia (Gilbert's syndrome)

2005 ◽  
Vol 20 (4) ◽  
pp. 327-331 ◽  
Author(s):  
Tsuyoshi Miyaoka ◽  
Rei Yasukawa ◽  
Takumi Mihara ◽  
Shoichi Mizuno ◽  
Hideaki Yasuda ◽  
...  
Keyword(s):  
Temporal Cortex ◽  
Inversion Recovery ◽  
Healthy Population ◽  
Mr Images ◽  
Unconjugated Hyperbilirubinemia ◽  
Gilbert’S Syndrome ◽  
Gilbert's Syndrome ◽  
Fluid Attenuated Inversion Recovery ◽  
Almost All ◽  
Signal Intensities

AbstractBackgroundPatients with schizophrenia show a significantly higher frequency of hyperbilirubinemia the patients suffering from other psychiatric disorders and the general healthy population. The objective of the current study was to determine whether patients with schizophrenia-associated idiopathic unconjugated hyperbilirubinemia (Gilbert's syndrome, GS) have specific changes in signal intensities on fluid-attenuated inversion-recovery (FLAIR) magnetic resonance (MR) images.MethodsAxial 5-mm-thick FLAIR MR images from schizophrenia patients with GS (n = 18) and schizophrenia patients without GS (n = 18), all diagnosed according to DSM-IV criteria, were compared with age- and sex-matched non-psychiatric controls (n = 18). Signal intensities in the hippocampus, amygdala, caudate, putamen, thalamus, cingulate gyrus, and insula were graded relative to cortical signal intensity in the frontal lobe.ResultsCompared to both schizophrenia patients without GS and normal controls, the schizophrenia patients with GS showed significantly increased signal intensities in almost all regions studied.ConclusionPatients with schizophrenia-associated GS have specific changes of signal intensities on FLAIR MR images, suggesting that schizophrenia with GS produces changes in the fronto-temporal cortex, limbic system, and basal ganglia.

EXTENT OF SURGICAL RESECTION IS INDEPENDENTLY ASSOCIATED WITH SURVIVAL IN PATIENTS WITH HEMISPHERIC INFILTRATING LOW-GRADE GLIOMAS

Neurosurgery ◽  
2008 ◽  
Vol 63 (4) ◽  
pp. 700-708 ◽  
Author(s):  
Matthew J. McGirt ◽  
Kaisorn L. Chaichana ◽  
Frank J. Attenello ◽  
Jon D. Weingart ◽  
Khoi Than ◽  
...  
Keyword(s):  
Confidence Interval ◽  
Surgical Resection ◽  
Inversion Recovery ◽  
Malignant Degeneration ◽  
Low Grade ◽  
Total Resection ◽  
Free Survival ◽  
Signal Abnormality ◽  
Fluid Attenuated Inversion Recovery ◽  
Extent Of Surgical Resection

ABSTRACT OBJECTIVE It remains unknown whether the extent of surgical resection affects survival or disease progression in patients with supratentorial low-grade gliomas. METHODS We conducted a retrospective cohort study (n = 170) between 1996 and 2007 at a single institution to determine whether increasing extent of surgical resection was associated with improved progression-free survival (PFS) and overall survival (OS). Surgical resection of gliomas defined as gross total resection (GTR) (complete resection of the preoperative fluid-attenuated inversion recovery signal abnormality), near total resection (NTR) (<3-mm thin residual fluid-attenuated inversion recovery signal abnormality around the rim of the resection cavity only), or subtotal resection (STR) (residual nodular fluid-attenuated inversion recovery signal abnormality) based on magnetic resonance imaging performed less than 48 hours after surgery. Our main outcome measures were OS, PFS, and malignant degeneration-free survival (conversion to high-grade glioma). RESULTS One hundred thirty-two primary and 38 revision resections were performed for low-grade astrocytomas (n = 93) or oligodendrogliomas (n = 77). GTR, NTR, and STR were achieved in 65 (38%), 39 (23%), and 66 (39%) cases, respectively. GTR versus STR was independently associated with increased OS (hazard ratio, 0.36; 95% confidence interval, 0.16–0.84; P = 0.017) and PFS (HR, 0.56; 95% confidence interval, 0.32–0.98; P = 0.043) and a trend of increased malignant degeneration-free survival (hazard ratio, 0.46; 95% confidence interval, 0.20–1.03; P = 0.060). NTR versus STR was not independently associated with improved OS, PFS, or malignant degeneration-free survival. Five-year OS after GTR, NTR, and STR was 95, 80, 70%, respectively, and 10-year OS was 76, 57, and 49%, respectively. After GTR, NTR, and STR, median time to tumor progression was 7.0, 4.0, and 3.5 years, respectively. Median time to malignant degeneration after GTR, NTR, and STR was 12.5, 5.8, and 7 years, respectively. CONCLUSION GTR was associated with a delay in tumor progression and malignant degeneration as well as improved OS independent of age, degree of disability, histological subtype, or revision versus primary resection. GTR should be safely attempted when not limited by eloquent cortex.

scholarly journals Automated White Matter Hyperintensity Detection in Multiple Sclerosis Using 3D T2 FLAIR

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Yi Zhong ◽  
David Utriainen ◽  
Ying Wang ◽  
Yan Kang ◽  
E. Mark Haacke
Keyword(s):  
Multiple Sclerosis ◽  
White Matter ◽  
Gray Matter ◽  
Signal Intensity ◽  
High Spatial Frequency ◽  
Inversion Recovery ◽  
White Matter Hyperintensity ◽  
Mr Images ◽  
Automated Algorithm ◽  
Fluid Attenuated Inversion Recovery

White matter hyperintensities (WMH) seen on T2WI are a hallmark of multiple sclerosis (MS) as it indicates inflammation associated with the disease. Automatic detection of the WMH can be valuable in diagnosing and monitoring of treatment effectiveness. T2 fluid attenuated inversion recovery (FLAIR) MR images provided good contrast between the lesions and other tissue; however the signal intensity of gray matter tissue was close to the lesions in FLAIR images that may cause more false positives in the segment result. We developed and evaluated a tool for automated WMH detection only using high resolution 3D T2 fluid attenuated inversion recovery (FLAIR) MR images. We use a high spatial frequency suppression method to reduce the gray matter area signal intensity. We evaluate our method in 26 MS patients and 26 age matched health controls. The data from the automated algorithm showed good agreement with that from the manual segmentation. The linear correlation between these two approaches in comparing WMH volumes was found to beY=1.04X+1.74  (R2=0.96). The automated algorithm estimates the number, volume, and category of WMH.

scholarly journals Multiple sclerosis: High prevalence of the ‘central vein’ sign in white matter lesions on susceptibility-weighted images

2018 ◽  
Vol 31 (4) ◽  
pp. 356-361 ◽  
Author(s):  
Gianvincenzo Sparacia ◽  
Francesco Agnello ◽  
Angelo Gambino ◽  
Martina Sciortino ◽  
Massimo Midiri
Keyword(s):  
Multiple Sclerosis ◽  
White Matter ◽  
Magnetic Resonance ◽  
Small Vessel Disease ◽  
White Matter Lesions ◽  
Magnetic Resonance Images ◽  
Inversion Recovery ◽  
Central Vein ◽  
Fluid Attenuated Inversion Recovery ◽  
The Difference

Purpose The aim of this study was to determine the occurrence and distribution of the ‘central vein’ sign in white matter lesions on susceptibility-weighted magnetic resonance images in patients with multiple sclerosis (MS) and cerebral small vessel disease (CSVD). Materials and methods T2-weighted and fluid-attenuated inversion recovery magnetic resonance images of 19 MS patients and 19 patients affected by CSVD were analysed for the presence and localisation of focal hyperintense white matter lesions. Lesions were subdivided into periventricular or non-periventricular (juxtacortical, subcortical, deep white matter and cerebellar) distributed. The number and localisation of lesions presenting with the central vein sign were recorded and compared between MS and CSVD lesions. Results A total of 313 MS patients and 75 CSVD lesions were identified on T2-weighted and fluid-attenuated inversion recovery magnetic resonance images. The central vein sign was found in 128 MS lesions (40.9%), and the majority of them (71/128, 55.5%) had a periventricular distribution. The central vein sign was found in 22 out of 75 (29.3%) CSVD lesions, and periventricular distribution was seen in six out of 22 (27.2%) CSVD lesions. The difference in the proportion of white matter hyperintense lesions that presented with the central vein sign on susceptibility-weighted images in patients with MS and CSVD was statistically different, and a significantly higher number of MS patients presented with lesions with the central vein sign compared to CSVD patients. Conclusion The presence of the central vein sign on susceptibility-weighted images for MS lesions improves the understanding of the periventricular distribution of MS lesions and could contribute as adjunctive diagnostic criteria for MS disease.

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