scholarly journals Three-dimensional endoanal ultrasound in complex anorectal fistulas

2016 ◽  
Vol 63 (1) ◽  
pp. 75-81
Author(s):  
Giulio Santoro
Keyword(s):  
Fistulous Tract ◽  
Three Dimensional ◽  
Ease Of Use ◽  
Endoanal Ultrasound ◽  
Anal Continence ◽  
Anal Fistulas ◽  
Wide Availability ◽  
Colorectal Surgeons ◽  
Perianal Sepsis ◽  
Complex Anal Fistulas

The management of complex anorectal fistulas is associated with potential risk of fecal incontinence and recurrences. Understanding type and height of the fistulous tract has clinical relevance for colorectal surgeons in order to select the optimal surgical approach. History and physical examination along with selective imaging to delineate the anatomy of the fistula are critical to individualize the patient?s treatment. Three-dimensional endoanal ultrasound provides an accurate and reproducible assessment of perianal sepsis and in many cases, the result is not different from that of MRI. Due to higher panoramicity, multiplanar reconstruction allows to visualize the fistula tracts in the context of the surrounding structures. Ultrasound has several important advantages: relative ease of use, minimal discomfort, cost-effectiveness, relatively non-time consuming, and wide availability in the clinical setting. This modality has a favourable impact on the outcome of surgical treatment for complex anal fistulas reducing the recurrence rate, minimizing postoperative complications and preserving anal continence.

Use of three-dimensional virtual images for planning surgery of complex anal fistulas: a new technology available via smartphone

2019 ◽  
Vol 23 (8) ◽  
pp. 775-778 ◽  
Author(s):  
E. C. Sousa Júnior ◽  
W. M. N. Eulálio Filho ◽  
A. T. Nogueira ◽  
B. A. Rocha ◽  
A. D. Meneses
Keyword(s):  
New Technology ◽  
Three Dimensional ◽  
Anal Fistulas ◽  
Virtual Images ◽  
Complex Anal Fistulas

Three-dimensional endoanal ultrasound is accurate and reproducible in determining type and height of anal fistulas

2017 ◽  
Vol 19 (4) ◽  
pp. 378-384 ◽  
Author(s):  
M. Kołodziejczak ◽  
G. A. Santoro ◽  
A. Obcowska ◽  
Z. Lorenc ◽  
M. Mańczak ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Endoanal Ultrasound ◽  
Anal Fistulas

scholarly journals Magnetic resonance imaging template to standardize reporting of anal fistulas

2021 ◽  
Author(s):  
I. Sudoł-Szopińska ◽  
G. A. Santoro ◽  
M. Kołodziejczak ◽  
A. Wiaczek ◽  
U. Grossi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Treatment Strategies ◽  
Cross Sectional Study ◽  
Resonance Imaging ◽  
Anal Fistulas ◽  
Cross Sectional ◽  
Radiology Reports ◽  
Colorectal Surgeons ◽  
Magnetic Resonance Imaging Mri

AbstractAnal fistula (AF) is a common referral to colorectal surgeons. Management remains challenging and sometimes controversial. Magnetic resonance imaging (MRI) is commonly performed in initial workup for AF. However, reports often lack key information for guiding treatment strategies. It has been shown that with structured radiology reports, there is less missing information. We present a structured MRI template report including 8 key descriptors of anal fistulas, whose effectiveness and acceptability are being assessed in a cross-sectional study (NCT04541238).

scholarly journals Imaging in Propeller Flap Surgery

2020 ◽  
Vol 34 (03) ◽  
pp. 145-151
Author(s):  
Shimpei Ono ◽  
Hiroyuki Ohi ◽  
Rei Ogawa
Keyword(s):  
Low Cost ◽  
Three Dimensional ◽  
Duplex Sonography ◽  
Computed Tomographic Angiography ◽  
Ease Of Use ◽  
Computed Tomographic ◽  
Imaging Tool ◽  
Preoperative Mapping ◽  
Flap Design ◽  
Tomographic Angiography

AbstractSince propeller flaps are elevated as island flaps and most often nourished by a single perforator nearby the defect, it is challenging to change the flap design intraoperatively when a reliable perforator cannot be found where expected to exist. Thus, accurate preoperative mapping of perforators is essential in the safe planning of propeller flaps. Various methods have been reported so far: (1) handheld acoustic Doppler sonography (ADS), (2) color duplex sonography (CDS), (3) perforator computed tomographic angiography (P-CTA), and (4) magnetic resonance angiography (MRA). To facilitate the preoperative perforator assessment, P-CTA is currently considered as the gold standard imaging tool in revealing the three-dimensional anatomical details of perforators precisely. Nevertheless, ADS remains the most widely used tool due to its low cost, faster learning, and ease of use despite an undesirable number of false-positive results. CDS can provide hemodynamic characteristics of the perforator and is a valid and safer alternative particularly in patients in whom ionizing radiation and/or contrast exposure should be limited. Although MRA is less accurate in detecting smaller perforators of caliber less than 1.0 mm and the intramuscular course of perforators at the present time, MRA is expected to improve in the future due to the recent developments in technology, making it as accurate as P-CTA. Moreover, it provides the advantage of being radiation-free with fewer contrast reactions.

scholarly journals Effectiveness of the ligation of intersphincteric fistula tract (LIFT) in the treatment of anal fistula: initial results

2014 ◽  
Vol 27 (2) ◽  
pp. 101-103 ◽  
Author(s):  
Sergio Danilo Tanahara TOMIYOSHI ◽  
Carlos Henrique Marques DOS SANTOS
Keyword(s):  
Fecal Incontinence ◽  
Anal Fistula ◽  
Anorectal Manometry ◽  
Fistulous Tract ◽  
Complete Healing ◽  
Fistula Tract ◽  
Anal Fistulas ◽  
Intersphincteric Fistula ◽  
The Mean ◽  
Initial Results

BACKGROUND: The abscesses and anal fistulas represent about 70% of perianal suppuration, with an estimated incidence of 1/10000 inhabitants per year and representing 5% of queries in coloproctology. AIM: To evaluate the effectiveness of the interesphincteric ligation technique of the fistulous tract in the treatment of anal fistula. METHODS: The records of eight patients who underwent this technique, evaluating age, gender and presence of incontinence were studied. Was named technical first-step the passage of cotton thread to promote the correct individualization of the fistula and, as the second, the surgical procedure. RESULTS: Two patients were men and eight women. The mean age was 42.8 years. Of these, seven (87.5%) had complete healing of the fistula; six were cured only with this procedure and one required additional operation with simple fistulotomy. Only one patient developed fecal incontinence which was documented by anorectal manometry. There were no deaths in this series. CONCLUSION: The interesphincteric ligation technique of the fistulous tract proved to be effective for the treatment of anal fistula and should not be discouraged despite the occurrence of eventual fecal incontinence.

scholarly journals Fecal diversion in complex anal fistulas: Is there a way to avoid it?

2021 ◽  
Vol 9 (25) ◽  
pp. 7306-7310
Author(s):  
Pankaj Garg ◽  
Vipul D Yagnik ◽  
Sushil Dawka
Keyword(s):  
Fecal Diversion ◽  
Anal Fistulas ◽  
Complex Anal Fistulas

scholarly journals Cardio-Oncology: The Role of Echocardiography in Cancer Patients

2021 ◽  
Author(s):  
Theodoros Ntoskas
Keyword(s):  
Cancer Therapy ◽  
Cancer Patients ◽  
Cardiac Imaging ◽  
Early Recognition ◽  
Cardiac Injury ◽  
Three Dimensional ◽  
Cardiovascular Complications ◽  
Cardiac Events ◽  
Ongoing Research ◽  
Wide Availability

Cardio-oncology is a rapidly emerging medical field that focusses on the improvement of the quality of life of cancer patients by preventing and treating the adverse cardiovascular complications of cancer therapy. Early recognition of cancer therapy-related cardiac dysfunction (CTRCD) provides an opportunity to mitigate cardiac injury and risk of developing late cardiac events. Cardiac imaging, and in particular, transthoracic echocardiography, plays an essential role in the baseline assessment, the detection and the surveillance of CRTCD in patients during and after the cancer therapy. Although the frequency of screening for the cardiotoxicity in patients undergoing active treatments and cancer survivors remains a topic of debate and ongoing research, echocardiography continues to be the leader for continuous monitoring by imaging due to the wide availability, lack of exposure to radiation, ability to recognise the effects on cardiac function and assess haemodynamics and other cardiac structures. The cardiac imaging applied to cardio-oncology includes standard and advanced (speckle tracking and three-dimensional (3D)) echocardiography.

P3DOCK: a protein–RNA docking webserver based on template-based and template-free docking

2019 ◽  
Vol 36 (1) ◽  
pp. 96-103 ◽  
Author(s):  
Jinfang Zheng ◽  
Xu Hong ◽  
Juan Xie ◽  
Xiaoxue Tong ◽  
Shiyong Liu
Keyword(s):  
Success Rate ◽  
Clustering Algorithm ◽  
Hybrid Methods ◽  
3D Structure ◽  
Three Dimensional ◽  
Protein Docking ◽  
Ease Of Use ◽  
Supplementary Information ◽  
Main Function ◽  
Rna Interaction

AbstractMotivationThe main function of protein–RNA interaction is to regulate the expression of genes. Therefore, studying protein–RNA interactions is of great significance. The information of three-dimensional (3D) structures reveals that atomic interactions are particularly important. The calculation method for modeling a 3D structure of a complex mainly includes two strategies: free docking and template-based docking. These two methods are complementary in protein–protein docking. Therefore, integrating these two methods may improve the prediction accuracy.ResultsIn this article, we compare the difference between the free docking and the template-based algorithm. Then we show the complementarity of these two methods. Based on the analysis of the calculation results, the transition point is confirmed and used to integrate two docking algorithms to develop P3DOCK. P3DOCK holds the advantages of both algorithms. The results of the three docking benchmarks show that P3DOCK is better than those two non-hybrid docking algorithms. The success rate of P3DOCK is also higher (3–20%) than state-of-the-art hybrid and non-hybrid methods. Finally, the hierarchical clustering algorithm is utilized to cluster the P3DOCK’s decoys. The clustering algorithm improves the success rate of P3DOCK. For ease of use, we provide a P3DOCK webserver, which can be accessed at www.rnabinding.com/P3DOCK/P3DOCK.html. An integrated protein–RNA docking benchmark can be downloaded from http://rnabinding.com/P3DOCK/benchmark.html.Availability and implementationwww.rnabinding.com/P3DOCK/P3DOCK.html.Supplementary informationSupplementary data are available at Bioinformatics online.

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