scholarly journals The development of internal fixation: Historical overview

2012 ◽  
Vol 59 (3) ◽  
pp. 9-13 ◽  
Author(s):  
Aleksandar Lesic ◽  
Slavisa Zagorac ◽  
Vesna Bumbasirevic ◽  
Marko Bumbasirevic
Keyword(s):  
Internal Fixation ◽  
New Technologies ◽  
18Th Century ◽  
Ancient Egypt ◽  
Fracture Treatment ◽  
Invasive Procedures ◽  
New Methods ◽  
Ancient Times ◽  
First Time ◽  
Biological Internal Fixation

Since the ancient times, man was faced with the problem of fracture treatment, which is first described in the records from ancient Egypt. Ever since, many treatment methods have been developed, but the real revolution in the fracture treatment was achieved by internal fixation. Since it was described for the first time, at the end of the 18th century, this method has continuously developed, but sterilization, radiographies, anaesthesiology, antibiotics made this surgery modern and safe. The great ideas and practical solutions of the new methods were done by Albin Lambotte, William Arbuthnot Lane, Robert Danis, William Hey Groves. They lead to the expansion of this method and truly made the principles for the future AO school. New methods, biological internal fixation, minimally invasive procedures, new technologies and devices for internal fixation are introduced in the surgical practice daily.

Imaging the Mind, Minding the Image: An Historical Introduction to Brain Imaging and the Law

2007 ◽  
Vol 33 (2-3) ◽  
pp. 171-192 ◽  
Author(s):  
Laura Stephens Khoshbin ◽  
Shahram Khoshbin
Keyword(s):  
New Technologies ◽  
Medical Science ◽  
Invasive Procedures ◽  
Brain Images ◽  
The Public ◽  
Human Behaviors ◽  
Technical Ability ◽  
Ancient Times ◽  
The Mind ◽  
The Brain

Since ancient times, people have yearned to attribute human behaviors to a physical source within the head. Recently, neuroimaging technologies have given us the technical ability to look at the living brain, its structures, and some of its functions without the need for invasive procedures. However, the science has a long way to go before these technologies can allow us fully to appreciate the anatomical and physiologic underpinnings of human thoughts, states of mind, motives, will, or behaviors.In this Article, we use an historical overview to introduce the various new technologies for imaging the brain. Today, the goal of medical science is the same as it has always been: to make medical technologies valid, useful, effective, and safe; and to guide appropriate uses while protecting the public from the misuse of them. Brain images are particularly vulnerable to misuse because they are so visually attractive. This visual power can easily result in misunderstanding about what the images show and what they mean.

Conference report: innovation, interaction … and a lot of data: first time reflections on Internet Librarian International, UK 2018

2019 ◽  
Vol 36 (2) ◽  
pp. 21-22
Author(s):  
Ray Harper
Keyword(s):  
Best Practice ◽  
New Technologies ◽  
Conference Report ◽  
Library Services ◽  
New Techniques ◽  
Content Type ◽  
Making A Difference ◽  
Analyse Data ◽  
Physical Spaces ◽  
First Time

Purpose The purpose of this paper is to summarise a number of presentations at Day 1 of the Internet Librarian International conference, London, UK (16 October 2018). This was the 20th conference in the series, and the three key themes included were the next-gen library and librarian; understanding users, usage and user experience; and inclusion and inspiration: libraries making a difference. Design/methodology/approach This paper reports from the viewpoint of a first-time attendee of the conference. This summarises the main issues raised by each presentation and draws out the key learning points for practical situations. Findings The conference covered a variety of practical ways in which libraries can use technology to support users and make decisions about services. These include developing interactive physical spaces which include augmented reality; introducing “chat-bots” to support users; using new techniques to analyse data; and piloting new ways to engage users (such as coding clubs). A key theme was how we use and harness data in a way that is ethical, effective and relevant to library services. Originality/value This conference focussed on practical examples of how library and information services across sectors and countries are innovating in a period of huge change. The conference gave delegates numerous useful ideas and examples of best practice and demonstrated the strength of the profession in adapting to new technologies and developments.

scholarly journals Innovating on Inhaled Bioequivalence: A Critical Analysis of the Current Limitations, Potential Solutions and Stakeholders of the Process

Pharmaceutics ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1051
Author(s):  
Jonattan Gallegos-Catalán ◽  
Zachary Warnken ◽  
Tania F. Bahamondez-Canas ◽  
Daniel Moraga-Espinoza
Keyword(s):  
New Technologies ◽  
Innovation Process ◽  
Cost Effective ◽  
Regulatory Agencies ◽  
Drug Products ◽  
Effective Strategies ◽  
Rate Analysis ◽  
Orally Inhaled Drug Products ◽  
Next Generation Impactor ◽  
First Time

Orally inhaled drug products (OIDPs) are an important group of medicines traditionally used to treat pulmonary diseases. Over the past decade, this trend has broadened, increasing their use in other conditions such as diabetes, expanding the interest in this administration route. Thus, the bioequivalence of OIDPs is more important than ever, aiming to increase access to affordable, safe and effective medicines, which translates into better public health policies. However, regulatory agencies leading the bioequivalence process are still deciding the best approach for ensuring a proposed inhalable product is bioequivalent. This lack of agreement translates into less cost-effective strategies to determine bioequivalence, discouraging innovation in this field. The Next-Generation Impactor (NGI) is an example of the slow pace at which the inhalation field evolves. The NGI was officially implemented in 2003, being the last equipment innovation for OIDP characterization. Even though it was a breakthrough in the field, it did not solve other deficiencies of the BE process such as dissolution rate analysis on physiologically relevant conditions, being the last attempt of transferring technology into the field. This review aims to reveal the steps required for innovation in the regulations defining the bioequivalence of OIDPs, elucidating the pitfalls of implementing new technologies in the current standards. To do so, we collected the opinion of experts from the literature to explain these trends, showing, for the first time, the stakeholders of the OIDP market. This review analyzes the stakeholders involved in the development, improvement and implementation of methodologies that can help assess bioequivalence between OIDPs. Additionally, it presents a list of methods potentially useful to overcome some of the current limitations of the bioequivalence standard methodologies. Finally, we review one of the most revolutionary approaches, the inhaled Biopharmaceutical Classification System (IBCs), which can help establish priorities and order in both the innovation process and in regulations for OIDPs.

Business model of garment enterprises: a scientometric review

2021 ◽  
Vol 91 (13-14) ◽  
pp. 1609-1626
Author(s):  
Yuran Jin ◽  
Xiangye Song ◽  
Jinhuan Tang ◽  
Xiaodong Dong ◽  
Huisheng Ji
Keyword(s):  
Conference Proceedings ◽  
Social Science ◽  
Business Model ◽  
Western Europe ◽  
Business Models ◽  
New Technologies ◽  
Citation Index ◽  
The United States ◽  
Fast Fashion ◽  
First Time

The research on the business model of garment enterprises (BMGE) has expanded rapidly in the last decade. However, there is still a lack of comprehensive reviews of it, let alone visual research. Based on scientometrics, in this paper 118 papers and their 4803 references from Science Citation Index Expanded, Social Sciences Citation Index, Conference Proceedings Citation Index—Science, and Conference Proceedings Citation Index—Social Science & Humanities for the period 2010–2020 about the BMGE were analyzed by visualizing the co-cited references, co-occurrence keywords, burst references, dual-map overlays, and more with CiteSpace, Google Maps, and VOSviewer. The research revealed the intellectual landscapes of the BMGE for the first time and mapped the landmark papers, hotspots and trends, national or regional distributions and their cooperation networks, highly cited authors, and prestigious journals and disciplines related to the BMGE. The results show that the biggest hotspot is the fast fashion business model; social responsibility, smart fashion, Internet of Things, and sharing fashion are the main emerging hotspots; and the research focuses has evolved from traditional business models to business models driven by new technologies, then to new issues such as circular economy models. The institutions are mainly distributed in China, the United States, and Western Europe, and there is cooperation between more than 11 countries. The most popular disciplines are economics and politics, while psychology, education, and social science are the essential basic disciplines. The Journal of Cleaner Production and Journal of Fashion Marketing and Management, among others, actively promoted the research.

scholarly journals Efficient TALEN-mediated gene knockin at the bovine Y chromosome and generation of a sex-reversal bovine

2021 ◽  
Author(s):  
Ming Wang ◽  
ZhaoLin Sun ◽  
Fangrong Ding ◽  
Haiping Wang ◽  
Ling Li ◽  
...  
Keyword(s):  
Y Chromosome ◽  
Nuclear Transfer ◽  
Sex Reversal ◽  
Practical Application ◽  
Transcription Activator ◽  
New Methods ◽  
Fetal Fibroblasts ◽  
Male Phenotype ◽  
Solid Foundation ◽  
First Time

AbstractFunctional elucidation of bovine Y-chromosome genes requires available genome editing technologies. Meanwhile, it has yet to be proven whether the bovine Sry gene is the main or single factor involved in the development of the male phenotype in bovine. Here, we efficiently knocked out four Y-linked genes (Sry, ZFY, DDX3Y, and EIF2S3Y) in bovine fetal fibroblasts (BFFs) with transcription activator-like effector nucleases (TALENs) individually. Furthermore, we used TALEN-mediated gene knockin at the Sry gene and generated a sex-reversal bovine by somatic cell nuclear transfer (SCNT). The resulting bovine had only one ovary and was sterile. We demonstrate, for the first time, that the Sry gene is an important sex-determining gene in bovine. Our method lays a solid foundation for detecting the biology of the bovine Y chromosome, as it may provide an alternative biological model system for the study of mammalian sex determination, and new methods for the practical application in agricultural, especially for sex predetermination.

Research on the Key Technologies for New Large Dual-Platen High-Precision Clamping System

2010 ◽  
Vol 97-101 ◽  
pp. 64-68
Author(s):  
Jian Chen ◽  
Jin Wang ◽  
Guo Dong Lu ◽  
Zheng Qi Ling
Keyword(s):  
High Precision ◽  
Large Scale ◽  
New Technologies ◽  
Impact Factors ◽  
Adaptive Correction ◽  
Hydraulic Servo ◽  
New Type ◽  
Clamping System ◽  
Plastic Parts ◽  
First Time

High- precision and large scale are the developing trend for injection molding machine clamping system .This paper compared the characteristics of three-platen toggle and dual-platen hydraulic clamping system. The key impact factors that effecting plastic parts` precision from clamping system were discussed systematically first time. Based on these analyses, a new clamping system has been proposed and manufactured to improve the plastics parts` precision, including three new technologies: new type dual-platen structure, parallelism adaptive correction technology and numerical controlled hydraulic servo system technology. It has been applied in practical machine successfully, and experiment result proves that it is effective enough to satisfying the high-precision molding of large plastics parts.

COMMERCIAL FAUNA OF WA-TERBODIES IN THE MOSCOW RIVER BASIN IN THE SECOND HALF OF THE 18th CENTURY

2021 ◽  
pp. 94-112
Author(s):  
N. Ozerova
Keyword(s):  
River Basin ◽  
Fish Species ◽  
18Th Century ◽  
Commercial Fish ◽  
Acipenser Ruthenus ◽  
Land Survey ◽  
Ancient Times ◽  
In The Beginning ◽  
Almost All ◽  
Moscow River

Based on the data from economic notes to the General Land Survey, the ranges of commercial fish and crayfish species that inhabited waterbodies of the Moscow River basin in the second half of the 18th century are reconstructed. Eighteen maps showing the distribution of 22 fish species, including Acipenser ruthenus L., Abramis brama L., Barbatula barbatula L., Lota lota L., Sander lucioperca L. and others are compiled. Comparison of commercial fish species that lived in the Moscow River basin in the second half of the 18th century with data from ichthyological studies in the beginning of the XXI century and materials of archaeological surveys shows that almost all of these species have lived in the Moscow River basin since ancient times and have survived to the present day.

"Itzt kommen die Soldaten"

2019 ◽  
Author(s):  
Tilman Venzl
Keyword(s):  
Literary History ◽  
18Th Century ◽  
Military History ◽  
Form And Function ◽  
Social Structural ◽  
History Of ◽  
The Subject ◽  
And Function ◽  
The Military ◽  
First Time

In the 18th century, as many as 300 German-language plays were produced with the military and its contact and friction with civil society serving as focus of the dramatic events. The immense public interest these plays attracted feeds not least on the fundamental social structural change that was brought about by the establishment of standing armies. In his historico-cultural literary study, Tilman Venzl shows how these military dramas literarily depict complex social processes and discuss the new problems in an affirmative or critical manner. For the first time, the findings of the New Military History are comprehensively included in the literary history of the 18th century. Thus, the example of selected military dramas – including Lessing's Minna von Barnhelm and Lenz's Die Soldaten – reveals the entire range of variety characterizing the history of both form and function of the subject.

ONLINE EXHIBITION METROLEXPO-2020. ACCURATE MEASUREMENTS ARE THE BASIS OF QUALITY AND SAFETY

2021 ◽  
pp. 50-57
Author(s):  
V. I. Matveev
Keyword(s):  
Measuring Equipment ◽  
Technical Diagnostics ◽  
Quality And Safety ◽  
New Methods ◽  
Analytical Studies ◽  
Functional Control ◽  
First Time

The article summarizes the results of the MetrolExpo exhibition, which was held for the first time online. The event focused on instrumentation-demonstration and discussion of the possibilities of modern measuring equipment, analysis of new methods and technologies of accurate measurements that have appeared in recent years. The latest developments, devices and systems for conducting measurements, tests, technical diagnostics, analytical studies, production and functional control from the largest Russian and foreign manufacturers were demonstrated.

Sign in / Sign up

Export Citation Format

Share Document