scholarly journals Cardiac myxoma: The influence of surgical technique on long-term prognosis

2012 ◽  
Vol 64 (1) ◽  
pp. 1-6
Author(s):  
A. Mikic ◽  
P. Djukic ◽  
Biljana Obrenovic-Kircanski ◽  
Z. Gluvic ◽  
S. Putnik ◽  
...  

The aim of our study was to analyze the influence of different surgical techniques (left atriotomy, right atriotomy, biatrial approach and tumor basis solving) on early and late outcomes of patients operated on for cardiac myxoma. We evaluated 74 patients operated on for cardiac myxoma from 1982 through 2011. Sixty-six patients (89.19%) had left atrial myxoma and 8 (10.81%) right atrial myxoma. Histopathologic examination confirmed the diagnosis of atrial myxoma in all patients. In analyzing different surgical techniques we found that they had no influence on the duration of extracorporeal circulation and aortic cross-clamp time. Mortality analysis revealed: no intraoperative mortality; early mortality in 2 patients; late mortality in 12 patients. Survival after 29 years was 81.08%. There were no myxoma recurrences. 83.78% of the patients had functional improvement. In our opinion the best approach for right atrial myxoma is through right atriotomy, for left atrial myxoma through left atriotomy, with a biatrial approach for large tumors of the left atrium or when exploration of all 4 chambers is necessary. Subendocardial excision or thermocauterization was used for small tumors with bases less than 5 mm. Myxoma with a wider basis, depending on the localization, were partially resected at the atrial septum in the whole thickness or subendocardial excision of the tumor basis.

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Mazen E. Iskandar ◽  
Kamellia Dimitrova ◽  
Charles M. Geller ◽  
Darryl M. Hoffman ◽  
Robert F. Tranbaugh

A second recurrence of an excised nonfamilial cardiac myxoma is rare. Myxomatous cerebral aneurysms as a complication of cardiac myxomas are equally rare. A unique case of a patient with a total of 4 myxomas over a 20-year interval is presented. Her most recent presentation was a second recurrence of a left atrial myxoma, a de novo right atrial myxoma, and multiple cerebral myxomatous aneurysms. The challenging reconstruction of the normal anatomy was achieved with the use of porcine extracellular matrix patches. A diagnostic cerebral angiogram was later performed, and the aneurysms will be monitored for growth and possible intervention.


1997 ◽  
Vol 5 (3) ◽  
pp. 158-161
Author(s):  
Lim Yeong Phang ◽  
Tan Yong Seng

Cardiac myxomas are benign primary tumors of the heart that require prompt surgical intervention because of the possibility of developing syncope and hemodynamic or embolic complications. From 1 January 1981 to 31 December 1996, 20 patients (11 male and 9 female) underwent surgery for cardiac myxoma at Singapore General Hospital. Nineteen patients had a left atrial myxoma and 1 had a right atrial myxoma. Five patients had concomitant coronary artery disease including one with severe mitral regurgitation. Nine patients presented with progressive dyspnea, 5 with systemic embolus, 2 with syncope, 3 with congestive cardiac failure, and 1 with right ventricular failure. In 6 patients the diagnosis was established by cardiac catheterization and 14 patients were diagnosed by two-dimensional echocardiography. Cardiopulmonary bypass with mild to moderate systemic hypothermia was used for excision of the myxoma in all cases. Five patients had concomitant coronary artery bypass grafting and 2 had concomitant mitral valve replacement. There was no hospital mortality among patients who had only excision of the myxoma, including a patient who had a recurrence of her left atrial myxoma 5 years after the initial excision. There were 2 deaths in patients with coexisting cardiac and other diseases. Surgical excision is recommended for all cases of cardiac myxoma. There is little risk associated with this procedure. All patients should be followed up regularly with echocardiographic assessment as there is a small risk of recurrence.


2007 ◽  
Vol 135 (7-8) ◽  
pp. 401-406
Author(s):  
Aleksandar Mikic ◽  
Biljana Obrenovic-Kircanski ◽  
Mladen Kocica ◽  
Mile Vranes ◽  
Vesna Lackovic ◽  
...  

Introduction Cardiac myxomas are the most frequent primary tumors of the heart in adults, and they can be found in each of four cardiac chambers. Although biologically benign, due to their unfavorable localization, myxomas are considered "functionally malignant" tumors. Diagnosis of cardiac myxoma necessitates surgical treatment. Objective To analyze: 1) the influence of localization, size and consistency of cardiac myxomas on preoperative symptomatology; 2) the influence of different surgical techniques (left, right, biatrial approach, tumor basis solving) on early, and late outcomes. Method From 1982 to 2000, at the Institute for Cardiovascular Diseases, Clinical Center of Serbia, there were 46 patients with cardiac myxomas operated on, 67.4% of them women, mean age 47.1?16.3 years. The diagnosis was made according to clinical presentation, electrocardiographic and echocardiographic examinations and cardiac catheterization. Follow-up period was 4-18 (mean 7.8) years. Results In 41 (89.1%) patients, myxoma was localized in the left, while in 5 (10.9%), it was found in the right atrium. Average size was 5.8?3.8 cm (range: 1?1 cm to 9?8 cm) and 6?4 cm (range: 3?2 cm to 9?5 cm) for the left and right atrial myxomas, respectively. A racemous form predominated in the left (82.6%) and globous in the right (80%) atrium. Fatigue was the most common general (84.8%) and dyspnoea the most common cardiologic symptom (73.9%). Preoperative embolic events were present in 8 patients (4 pulmonary, 4 systemic). In our series: 1) different localization, size and consistency had no influence on the preoperative symptomatology; 2) surgical treatment applied, regardless of different approaches and basis solving, resulted in excellent functional improvements (63.1% patients in NYHA III and IV class preoperatively vs. 6.7% patients postoperatively) and had no influence on new postoperative rhythm disturbances (8.7% patients preoperatively vs. 24.4% patients postoperatively); 3) early (97.8%), and late survival rates (91.3%) were excellent; 4) there were no relapses during the follow-up period. Conclusion Localization, size and consistency had no influence on the preoperative symptomatology. Excellent survival rate with significant functional improvement, rare postoperative complications and no recurrences, justify the applied strategies of surgical approach and tumor basis solving in our series.


Author(s):  
Mijo Meter ◽  
Diana Meter ◽  
Toni Ceprnja ◽  
Dijana Perkovic

AbstractCardiac myxoma (CM) is the most frequent type of primary cardiac neoplasm and is responsible for 58 to 80% of primary cardiac tumors. The antiphospholipid syndrome (APS) occurs most commonly in the systemic lupus erythematosus but it can be also found in other conditions. The coexistence of CM and APS is rarely described in the literature. We report an unusual case of the left atrial myxoma and concomitant APS in a female patient who presented with right-sided hemiplegia. Although rare, we must think about the CM in patients with a newly diagnosed APS and left atrial mass. Nevertheless, we must make a distinction from other possible cardiac structures, especially atrial thrombus. Transthoracic echocardiography is the most frequently used initial imaging modality to detect CM. The aim of this case report was to emphasize that additional imaging modalities and multidisciplinary approach are mandatory in making a proper diagnosis and to choose a further treatment strategy.


2008 ◽  
Vol 9 (3) ◽  
pp. 415-416 ◽  
Author(s):  
Yigal Abramowitz ◽  
Gidon Perlman ◽  
Eli Levy ◽  
Ronen Beeri ◽  
Tova Chajek-Shaul ◽  
...  

2007 ◽  
Vol 13 (2) ◽  
pp. 179-184 ◽  
Author(s):  
J. Sedat ◽  
Y. Chau ◽  
A. Dunac ◽  
N. Gomez ◽  
L. Suissa ◽  
...  

A case of multiple cerebral aneurysms caused by left atrial myxoma is reported. We present the details of this case and discuss the hypothetical pathogenesis, radiological aspects and treatment of these neoplastic aneurysms.


2020 ◽  
Vol 23 (3) ◽  
pp. E292-E294
Author(s):  
Jin Shi ◽  
Yong Wang ◽  
Qiuyun Wang ◽  
Xiaohan Bing ◽  
Zengshan Ma

The patient was a 69-year-old male patient with cancer in the right lung and whose preoperative examination showed left atrial myxoma. Simultaneous surgery for both cardiac myxoma resection and a lobectomy by totally endoscopic surgery without robotic assistance was performed. First, the cardiac tumor on the heart was removed using a cardiopulmonary bypass (CPB), then a lobectomy without any new incisions was performed. This case provides evidence that in individual select patients, a left atrial myxoma resection and lobectomy can be performed under total endoscopy at the same time.


2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
R Gray ◽  
J Brassil ◽  
N Jepson

Abstract A 73-year-old female presented with sudden reduced level of consciousness on the background of rheumatoid arthritis and dyslipidaemia. On examination she had a Glascow Coma Score of 12 and an irregularly irregular pulse. The electrocardiograph confirmed atrial fibrillation and showed widespread T wave inversion. A computed tomography cerebral angiogram showed an acute basilar artery occlusion. She was transferred to a tertiary centre where she had successful endovascular clot retrieval. An urgent transthoracic echocardiogram (figure 1) showed apical hypertrophy, normal systolic function and a large right atrial mass. The left atrial size was normal. A transoesophageal echocardiogram (figure 3) confirmed a large pedunculated mobile mass with a hypermobile septum consistent with a patent foramen ovale. There was no right to left doppler flow, however the atrial mass obstructed the course, and a bubble study was positive. The cardiac magnetic resonance image (figure 2) showed a 47 x 48 mm pedunculated lesion within the right atrium, arising from the intraventricular septum, demonstrating moderate T2 signal intensity, and intermediate T1 signal intensity, with avid enhancement, consistent with a right atrial myxoma. There was increased apical wall thickening at 15mm which confirmed apical hypertrophic cardiomyopathy. An open surgical resection and left atrial appendage ligation was performed on day 11 of admission. Histopathology confirmed an atrial myxoma. She had an excellent neurological recovery with only mild diplopia. The mechanism of stroke was likely atrial fibrillation secondary to increased left atrial pressure from apical hypertrophic cardiomyopathy. However, the unexpected finding of a right atrial myxoma with a corresponding patent foramen ovale provides a second possible mechanism. Abstract P1699 Figure. Right atrial Myxoma


2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Simran Gupta ◽  
Ricky Ayala ◽  
Aakash Desai ◽  
Viraj I. Modi ◽  
Robert J. Nardino

Myxomas are benign, primary tumors of the heart. Atrial myxomas can present with a variety of clinical features including dyspnea, orthopnea, pulmonary edema, and pulmonary or systemic emboli. Constitutional symptoms such as fever and weight loss may also be present. We report the case of a young female presenting with headache, facial numbness, and vertigo, who was found to have a posterolateral medullary stroke secondary to a large left atrial cardiac myxoma.


2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Christina Maria Steger ◽  
Thomas Hager ◽  
Elfriede Ruttmann

Primary cardiac tumours are extremely rare with the most commonest being left atrial myxomas. In general, surgical resection is indicated, whenever the tumour formation is mobile and embolization can be suspected. Within 17280 patients receiving heart surgery at the Innsbruck Medical University, 78 patients (0.45%) underwent tumourectomy of primary cardiac tumours. The majority of patients (63) suffered from a left or right atrial myxoma, 12 showed a papillary fibroelastoma of the valves at echocardiographical or histological examination, 1 suffered from a hemangioma, 1 from a chemodectoma, and another one from a rhabdomyosarcoma. The mean age of cardiac tumour patients was 54.29 ± 13.28 years (ranging from 18 to 83 years). 67.95% of the patients were female and 32.05% were male. The majority of tumours were found incidentally; 97.44% of the patients showed no tumour recurrence.


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